Zobrazeno 1 - 10 of 37 pro vyhledávání: '"Chetan B, Sangani"'
1
Synthesis, Characterization and Molecular Modeling of Pyrazole-Quinoline Hybrids as New Class of Antibacterial, Antimicrobial, Anticancer Agents and DFT Study
Autor: Rajat Patel, Puja Sharma, Rohit R. Koshti, Akshay Vyas, Chetan B. Sangani
Publikováno v: Asian Journal of Chemistry. 35:828-838
A new series of pyrazole-quinoline hybrids were synthesized by a base-catalyzed cyclocondensation reaction through one-pot multi-component reaction, based on molecular hybridization techniques. All the compounds 10a-x were examined for in vitro antib
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::58c871d2d9542e4412f163143f27dd42
https://doi.org/10.14233/ajchem.2023.26894
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2
Synthesis, Biological Evaluation and Molecular Modeling of Novel Ethyl 2′-Amino-5′-oxo-1′- (4-phenylthiazol-2-yl)-2-(phenylthio)-1′,4′,5′,6′,7′,8′-hexahydro-[3,4′-biquinoline]-3′- carboxylate Derivatives and their Computational Quantum Mechanical Modelling
Autor: Puja Sharma, Rajat Patel, Rohit R. Koshti, Akshay Vyas, Chetan B. Sangani
Publikováno v: Asian Journal of Chemistry. 35:1320-1332
A new series of biquinoline-phenylthiazole hybrids were designed and synthesized by a base-catalyzed cyclocondensation through one-pot multicomponent reaction. All compounds were tested for in vitro antimicrobial and anticancer activities. Enzyme inh
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::31f7b7b78356662e452afa5db3a724c8
https://doi.org/10.14233/ajchem.2023.27650
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4
Synthesis of novel drug-like small molecules library based on 1
Autor: Tejasvi H. Parmar, Chetan B. Sangani, Mahesh Kulkarni
Publikováno v: Australian Journal of Chemistry. 75:276-284
A series of novel ‘drug-like’ small molecules based on 1H-benzo[d]imidazole derivatives bearing furan-2-yl, 4-piperidine and 5-aryl/aminoaryl substitutions were designed and synthesised. The key intermediate tert-butyl-4-(5-bromo-2-(furan-2-yl)-1
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b1bb0c7a43088edc7798b676303c1865
https://doi.org/10.1071/ch21238
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5
Synthesis, Biological Evaluation and Molecular Modeling of Pyrazole-Phthalazine Hybrid Derivatives Bearing 2-Aryloxy Quinoline Nucleus and their Computational Quantum Mechanical Modelling
Autor: Puja Sharma, Rajat Patel, Rohit R. Koshti, Akshay Vyas, Chetan B. Sangani
Publikováno v: Asian Journal of Chemistry. 34:3169-3182
In present work, the synthesis, characterization, antibacterial and anticancer activities of a novel series of 1H-pyrazolo[1,2-b]phthalazine-5,10-dione derivatives bearing 2-aryloxyquinoline nucleus (6a-l) is reported. In vitro antibacterial and anti
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c075155316aefbde90e5186982801b89
https://doi.org/10.14233/ajchem.2022.23981
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7
Synthesis, Characterization and Biological Activities of N-(4-(3,4-Dichlorophenoxy)-phenyl)-4-alkoxybenzamide Derivatives
Autor: Pradip C. Bhalodiya, Chetan B. Sangani, Hemant N. Patel
Publikováno v: Asian Journal of Organic & Medicinal Chemistry. 6:73-78
An alkoxy benzamide derivatives are have been synthesized in four steps. Alkylation, halo phenol coupling, nitro group reduction and acid amine coupling gave in decent yield. Likewise, these targets were synthesized by coupling of 4-(3,4-dichlorophen
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8dd9ccd353ed56025aecdcac35c334fd
https://doi.org/10.14233/ajomc.2021.ajomc-p309
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8
Bromodomain and BET family proteins as epigenetic targets in cancer therapy: their degradation, present drugs, and possible PROTACs
Autor: Poonam Bhadja, Naaser A. Y. Abduh, Mohd. Muddassir, Kunjal V. Soni, Abdullah Alarifi, Chetan B. Sangani, Mohd Afzal, Yongtao Duan
Publikováno v: RSC Advances. 11:612-636
Alteration in the pattern of epigenetic marking leads to cancer, neurological disorders, inflammatory problems etc. These changes are due to aberration in histone modification enzymes that function as readers, writers and erasers. Bromodomains (BDs)
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b71f4ca75cd427370d14b47915d5903
https://doi.org/10.1039/d0ra07971e
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9
Graphene, an epoch-making material in RFID technology: a detailed overview
Autor: Yongtao Duan, Yongfang Yao, Abhishek Dhar, Rohit L. Vekariya, Sayan Chakraborty, Bhavesh R. Pansuriya, Chetan B. Sangani
Publikováno v: New Journal of Chemistry. 45:18700-18721
Many researchers claim that graphene, a specially studied carbon allotrope, has a single layer of atoms organized in a two-dimensional honeycomb lattice. Because of its exceptional electronic and mechanical properties, it has a significant job to per
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e044990c7ac3b9d701105a274375f1f3
https://doi.org/10.1039/d1nj03226g
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10
Binary systems of non-mesogens with naphthalene derivatives
Autor: Ashish K. Prajapati, Yong fang Yao, Yongtao Duan, Hemant N. Patel, Chetan B. Sangani
Publikováno v: Molecular Crystals and Liquid Crystals. 712:31-42
Binary mixtures with both the components are non-mesogenic becomes an interesting and enlighten feature when they exhibit mesomorphism at ambient temperature. In the present study, we report five b...
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::117281f4d8000fd8407ad51ffbcf37c6
https://doi.org/10.1080/15421406.2020.1856503
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