Zobrazeno 1 - 10
of 74
pro vyhledávání: '"Chester W. Brown"'
Unmapped exome reads implicate a role for Anelloviridae in childhood HIV-1 long-term non-progression
Autor:
Savannah Mwesigwa, Lesedi Williams, Gaone Retshabile, Eric Katagirya, Gerald Mboowa, Busisiwe Mlotshwa, Samuel Kyobe, David P. Kateete, Eddie Mujjwiga Wampande, Misaki Wayengera, Sununguko Wata Mpoloka, Angella N. Mirembe, Ishmael Kasvosve, Koketso Morapedi, Grace P. Kisitu, Adeodata R. Kekitiinwa, Gabriel Anabwani, Moses L. Joloba, Enock Matovu, Julius Mulindwa, Harry Noyes, Gerrit Botha, Collaborative African Genomics Network (CAfGEN), TrypanoGEN Research Group, Chester W. Brown, Graeme Mardon, Mogomotsi Matshaba, Neil A. Hanchard
Publikováno v:
npj Genomic Medicine, Vol 6, Iss 1, Pp 1-9 (2021)
Abstract Human immunodeficiency virus (HIV) infection remains a significant public health burden globally. The role of viral co-infection in the rate of progression of HIV infection has been suggested but not empirically tested, particularly among ch
Externí odkaz:
https://doaj.org/article/ff623b751fa84b8e9c4699ec4ca85de2
Autor:
Rishika P. Sakaria, Parul G. Zaveri, Shannon Holtrop, Jie Zhang, Chester W. Brown, Eniko K. Pivnick
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
Kabuki syndrome is a rare multiple anomalies syndrome associated with mutations in KMT2D or KDM6A. It is characterized by infantile hypotonia, developmental delay and/or intellectual disability, long palpebral fissures with everted lateral third of t
Externí odkaz:
https://doaj.org/article/3611b586fd554653adde02332196254a
Autor:
Samuel Kyobe, Savannah Mwesigwa, Grace P. Kisitu, John Farirai, Eric Katagirya, Angella N. Mirembe, Lesego Ketumile, Misaki Wayengera, Fred Ashaba Katabazi, Edgar Kigozi, Edward M. Wampande, Gaone Retshabile, Busisiwe C. Mlotshwa, Lesedi Williams, Koketso Morapedi, Ishmael Kasvosve, Jacqueline Kyosiimire-Lugemwa, Betty Nsangi, Masego Tsimako-Johnstone, Chester W. Brown, Moses Joloba, Gabriel Anabwani, Lukhele Bhekumusa, Sununguko W. Mpoloka, Graeme Mardon, Mogomotsi Matshaba, Adeodata Kekitiinwa, Neil A. Hanchard
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
Human leucocyte antigen (HLA) class I molecules present endogenously processed antigens to T-cells and have been linked to differences in HIV-1 disease progression. HLA allelotypes show considerable geographical and inter-individual variation, as doe
Externí odkaz:
https://doaj.org/article/ff38e6237b2d42cabf9d412239a52899
Autor:
Gerald Mboowa, Savannah Mwesigwa, Eric Katagirya, Gaone Retshabile, Busisiwe C. Mlotshwa, Lesedi Williams, Adeodata Kekitiinwa, David Kateete, Eddie Wampande, Misaki Wayengera, Betty Nsangi Kintu, Grace P. Kisitu, Samuel Kyobe, Chester W. Brown, Neil A. Hanchard, Graeme Mardon, Moses Joloba, Gabriel Anabwani, Ed Pettitt, Masego Tsimako-Johnstone, Ishmael Kasvosve, Koketso Maplanka, Sununguko W. Mpoloka, Makhosazana Hlatshwayo, Mogomotsi Matshaba
Publikováno v:
AAS Open Research, Vol 1 (2018)
Background: Here, we describe how the Collaborative African Genomics Network (CAfGEN) of the Human Heredity and Health in Africa (H3Africa) consortium is using genomics to probe host genetic factors important to the progression of HIV and HIV-tubercu
Externí odkaz:
https://doaj.org/article/5abf5c8052074cd398adeb6d10ee244f
Autor:
Gerald Mboowa, Savannah Mwesigwa, Eric Katagirya, Gaone Retshabile, Busisiwe C. Mlotshwa, Lesedi Williams, Adeodata Kekitiinwa, David Kateete, Eddie Wampande, Misaki Wayengera, Betty Nsangi Kintu, Grace P. Kisitu, Samuel Kyobe, Chester W. Brown, Neil A. Hanchard, Graeme Mardon, Moses Joloba, Gabriel Anabwani, Ed Pettitt, Masego Tsimako-Johnstone, Ishmael Kasvosve, Koketso Maplanka, Sununguko W. Mpoloka, Makhosazana Hlatshwayo, Mogomotsi Matshaba
Publikováno v:
AAS Open Research, Vol 1 (2018)
Background: The Human Heredity and Health in Africa consortium (H3Africa) was conceived to facilitate the application of genomics technologies to improve health across Africa. Here, we describe how the Collaborative African Genomics Network (CAfGEN)
Externí odkaz:
https://doaj.org/article/be04a23b03b14af88c81be071fca9cde
Autor:
Samuel Kyobe, Grace Paul Kisitu, Savannah Mwesigwa, John Farirai, Eric Katagirya, Gaone Retshabile, Lesedi Williams, Angela Mirembe, Lesego Ketumile, Misaki Wayengera, John Mukisa, Gaseene Sebetso, Thabo Diphoko, Marion Amujal, Edgar Kigozi, Fred Ashaba Katabazi, Ronald Oceng, Busisiwe C. Mlotshwa, Koketso Morapedi, Jacqueline Kyosiimire-Lugemwa, Betty Nsangi, Edward Wampande, Masego Tsimako-Johnstone, Chester W. Brown, Ishmael Kasvosve, Moses Joloba, Gabriel Anabwani, Sununguko Wata Mpoloka, Graeme Mardon, Dithan Kiragga, Neil A. Hanchard, Mogomotsi Sandy Matshaba, Adeodata R. Kekitiinwa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a9b623ca84068cec16b03cf4460009a4
https://doi.org/10.2139/ssrn.4393692
https://doi.org/10.2139/ssrn.4393692
Autor:
Michelle Puchowicz, Joseph F. Pierre, Tamekia L. Jones, Roshan Kumari, Chester W. Brown, Qusai Al Abdallah, Maria Johnson Irudayam, Tahliyah S. Mims
Publikováno v:
The FASEB Journal. 35
Adipose tissue is the primary site of energy storage, playing important roles in health. While adipose research largely focuses on obesity, fat also has other critical functions, producing adipocytokines and contributing to normal nutrient metabolism
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64e3ef18d86f0e0dc3cea54b6879505c
https://doi.org/10.1096/fj.202101244r
https://doi.org/10.1096/fj.202101244r
Autor:
V. Reid Sutton, Katelyn Payne, Emily Chen, Xiaofei Song, Annick Raas-Rothschild, Elizabeth Mizerik, Shannon Holtrop, Margarita Nieto Moreno, Chester W. Brown, Nurit Assia Batzir, James R. Lupski, Richard H Scott, Jennifer E. Posey, Hilary J. Vernon, Neda Zadeh, Zeynep Coban Akdemir, Jill A. Rosenfeld
Publikováno v:
Am J Med Genet A
White-Sutton syndrome (WHSUS) is a recently-identified genetic disorder resulting from de novo heterozygous pathogenic variants in POGZ. Thus far, over 50 individuals have been reported worldwide, however phenotypic characterization and data regardin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c832b6f968e7f63091fa687e15de7d6b
https://doi.org/10.1002/ajmg.a.61380
https://doi.org/10.1002/ajmg.a.61380
Unmapped exome reads implicate a role for Anelloviridae in childhood HIV-1 long-term non-progression
Autor:
Mogomotsi Matshaba, Moses Joloba, Savannah Mwesigwa, Gabriel Anabwani, Lesedi Williams, Samuel Kyobe, Gerrit Botha, Graeme Mardon, David P. Kateete, Gaone Retshabile, Julius Mulindwa, Busisiwe C. Mlotshwa, Misaki Wayengera, Angella N. Mirembe, Enock Matovu, Neil A. Hanchard, Chester W. Brown, Grace P. Kisitu, Sununguko Wata Mpoloka, Harry Noyes, Eric Katagirya, Adeodata Kekitiinwa, Eddie M. Wampande, Ishmael Kasvosve, Koketso Morapedi, Gerald Mboowa
Publikováno v:
NPJ Genomic Medicine
npj Genomic Medicine, Vol 6, Iss 1, Pp 1-9 (2021)
npj Genomic Medicine, Vol 6, Iss 1, Pp 1-9 (2021)
Human immunodeficiency virus (HIV) infection remains a significant public health burden globally. The role of viral co-infection in the rate of progression of HIV infection has been suggested but not empirically tested, particularly among children. W
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9684df9b5ab0058420cc176468c027cf
http://europepmc.org/articles/PMC7979878
http://europepmc.org/articles/PMC7979878
Autor:
Daniel G. Tenen, Joanna R. DiSpirito, Christopher Jacobs, Zhaoming Deng, Pratik Aryal, Barbara B. Kahn, Deepti Ramachandran, Chester W. Brown, Amir Mina, Peter-James H. Zushin, Bruce M. Spiegelman, Jessica A. Hall, Hyun Cheol Roh, Julia F. Charles, T. Belchior de Oliveira, Linus T.-Y. Tsai, Bingyang Liu, Gerald I. Shulman, Evan D. Rosen, Shangyu Hong, Colin J Palmer, Alexander S. Banks
Publikováno v:
Cell Metab
Overnutrition and obesity promote adipose tissue dysfunction, often leading to systemic insulin resistance. The thiazolidinediones (TZDs) are a potent class of insulin-sensitizing drugs and ligands of PPARγ that improve insulin sensitivity, but thei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bab86f58c16ee1ec612d7990987155bc