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pro vyhledávání: '"Chester Jacobs"'
Autor:
Andrew M. Scharenberg, Laura Smith, Chester Jacobs, Karen Vo, Chandra Patel, Keith Abe, David J. Rawlings, West Samuel, Gene Uenishi, Troy R. Torgerson, Simon Gebremeskel, Cade E. Ito, Cornell Mallari, Greg Boucher, Karen Sommer, Samantha Chin, Luis Gamboa, Dariusz Wodziak, Basha Stankovich, Noelle Dahl, Rangoli Aeran, Greg J. Cost
Publikováno v:
Blood. 134:3355-3355
Regulatory T-cells (Treg) depend on signals from IL2 and their endogenous T-cell receptors to survive, proliferate, and maintain suppressive activity. We have developed a strategy for engineering effector CD4 T-cells into edited, regulatory-like T-ce