The rational design of novel 5-amino-2-oxindole derivatives with antiglaucomic activity.

Autor: Eremeev RO; Department of Chemistry, Lomonosov Moscow State University, 119992 Moscow, Russian Federation. Electronic address: roma.chem.dep@mail.ru., Beznos OV; Federal State Institute 'Helmholtz Moscow Research Institute of Eye Diseases' of the Russian Federation Ministry of Health, Moscow, Russian Federation., Efremov AM; Department of Chemistry, Lomonosov Moscow State University, 119992 Moscow, Russian Federation; Institute of Physiologically Active Compounds at Federal Research Center of Problems of Chemical Physics and Medicinal Chemistry, Russian Academy of Sciences (IPAC RAS), 142432 Chernogolovka, Moscow Region, Russian Federation., Chesnokova NB; Federal State Institute 'Helmholtz Moscow Research Institute of Eye Diseases' of the Russian Federation Ministry of Health, Moscow, Russian Federation., Lozinskaya NA; Department of Chemistry, Lomonosov Moscow State University, 119992 Moscow, Russian Federation. Electronic address: natalylozinskaya@mail.ru.

Publikováno v: Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2023 Jun 15; Vol. 90, pp. 129334. Date of Electronic Publication: 2023 May 18.

[The role of the endothelin system in the pathogenesis of eye diseases]

Autor: Beznos Ov, T.A. Pavlenko, A.V. Grigoryev, Chesnokova Nb

Publikováno v: Vestnik oftalmologii. 136(1)

The endothelin system (ES) plays a complex role in the pathogenesis of various eye diseases as a local regulator of vascular tone as well as many other physiological processes. Components of ES - endothelins and their receptors - can be found nearly

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::406c5faa3f384a617aefaeee6aec714f
https://pubmed.ncbi.nlm.nih.gov/32241978

[Pathogenetic role of multifunctional protein alpha-2-macroglobulin and its activity in tears and serum in age-related macular degeneration and proliferative diabetic retinopathy].

Autor: Neroev VV; Helmholtz National Medical Research Center of Eye Diseases, Moscow, Russia., Chesnokova NB; Helmholtz National Medical Research Center of Eye Diseases, Moscow, Russia., Neroeva NV; Helmholtz National Medical Research Center of Eye Diseases, Moscow, Russia., Beznos OV; Helmholtz National Medical Research Center of Eye Diseases, Moscow, Russia., Pavlenko TA; Helmholtz National Medical Research Center of Eye Diseases, Moscow, Russia., Okhotsimskaya TD; Helmholtz National Medical Research Center of Eye Diseases, Moscow, Russia., Utkina OA; Helmholtz National Medical Research Center of Eye Diseases, Moscow, Russia.

Publikováno v: Vestnik oftalmologii [Vestn Oftalmol] 2023; Vol. 139 (6), pp. 26-32.

Gamma-Synuclein Dysfunction Causes Autoantibody Formation in Glaucoma Patients and Dysregulation of Intraocular Pressure in Mice.

Autor: Pavlenko TA; Helmholtz Moscow Research Institute of Eye Diseases, Ministry of Health of the Russian Federation, 105062 Moscow, Russia., Roman AY; Institute of Physiologically Active Compounds at Federal Research Center of Problems of Chemical Physics and Medicinal Chemistry, Russian Academy of Sciences, 142432 Chernogolovka, Russia., Lytkina OA; Institute of Physiologically Active Compounds at Federal Research Center of Problems of Chemical Physics and Medicinal Chemistry, Russian Academy of Sciences, 142432 Chernogolovka, Russia., Pukaeva NE; Institute of Physiologically Active Compounds at Federal Research Center of Problems of Chemical Physics and Medicinal Chemistry, Russian Academy of Sciences, 142432 Chernogolovka, Russia.; Department of General and Cell Biology, Faculty of Medical Biology, Pirogov Russian National Research Medical University, 117997 Moscow, Russia., Everett MW; Department of General and Cell Biology, Faculty of Medical Biology, Pirogov Russian National Research Medical University, 117997 Moscow, Russia., Sukhanova IS; Institute of Physiologically Active Compounds at Federal Research Center of Problems of Chemical Physics and Medicinal Chemistry, Russian Academy of Sciences, 142432 Chernogolovka, Russia.; Department of General and Cell Biology, Faculty of Medical Biology, Pirogov Russian National Research Medical University, 117997 Moscow, Russia., Soldatov VO; Department of Pharmacology and Clinical Pharmacology, Belgorod State National Research University, 308015 Belgorod, Russia., Davidova NG; Helmholtz Moscow Research Institute of Eye Diseases, Ministry of Health of the Russian Federation, 105062 Moscow, Russia., Chesnokova NB; Helmholtz Moscow Research Institute of Eye Diseases, Ministry of Health of the Russian Federation, 105062 Moscow, Russia., Ovchinnikov RK; Institute of Physiologically Active Compounds at Federal Research Center of Problems of Chemical Physics and Medicinal Chemistry, Russian Academy of Sciences, 142432 Chernogolovka, Russia.; Department of General and Cell Biology, Faculty of Medical Biology, Pirogov Russian National Research Medical University, 117997 Moscow, Russia., Kukharsky MS; Institute of Physiologically Active Compounds at Federal Research Center of Problems of Chemical Physics and Medicinal Chemistry, Russian Academy of Sciences, 142432 Chernogolovka, Russia.; Department of General and Cell Biology, Faculty of Medical Biology, Pirogov Russian National Research Medical University, 117997 Moscow, Russia.

Publikováno v: Biomedicines [Biomedicines] 2022 Dec 27; Vol. 11 (1). Date of Electronic Publication: 2022 Dec 27.

The influence of melatonin and dexamethasone instillations on the clinical course of uveitis and the biochemical processes in the aqueous humour of the anterior chamber of the eye (an experimental study)

Autor: Gulmira Alimovna Beyshenova, Beznos Ov, Chesnokova Nb

Publikováno v: Russian Pediatric Ophthalmology. 11:27-32

Introduction. The problem of the treatment of uveitis has the important socio-medical implications bearing in mind the high prevalence of this pathological condition frequently affecting the subjects of the employable age. Uveitis is characterized by

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::05413dc8815755b97a5b9754fc37d310
https://doi.org/10.18821/1993-1859-2016-11-1-27-32