Zobrazeno 1 - 10 of 62 pro vyhledávání: '"Chesik, D."'
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IGF-1 regulates cAMP levels in astrocytes through a beta2-adrenergic receptor-dependant mechanism
Autor: Chesik, D., Wilczak, N., De Keyser, Jacques
We have recently demonstrated that neonatal astrocytes derived from mice lacking beta-2 adrenergic receptors (beta(2)AR) possess higher proliferation rates, as compared to wild-type cells, an attribute that was shown to involve insulin-like growth fa
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3848::3d2745b18051341a93fb1e4256474d1a
https://hdl.handle.net/20.500.14017/81c470e7-da65-45c3-b2a9-d1498536caf1
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4
Insulin-like growth factor system regulates oligodendroglial cell behavior: therapeutic potential in CNS
Autor: Chesik, D., De Keyser, Jacques, Wilczak, N.
Amongst the many soluble extracellular factors stimulating intracellular signal transduction pathways and driving cellular processes such as proliferation, differentiation and survival, insulin-like growth factors (IGFs) stand out as indispensable fa
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3848::f89fff61809454ab343d0e087d2098a9
https://hdl.handle.net/20.500.14017/c2adadf5-bfae-4ffe-bc88-05649eaecfdf
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5
Insulin-like growth factor binding protein-I-6 expression in activated microglia
Autor: Chesik, D., Glazenburg, K., Wilczak, N., Geeraedts, Felix, De Keyser, J.
Publikováno v: Neuroreport, 15(6), 1033-1037. LIPPINCOTT WILLIAMS & WILKINS
In the CNS insulin-like growth factor-1 (IGF-1) enhances survival of neurons, promotes myelin synthesis and acts as a mitogen for microglia. The effects of IGF-1 are regulated by a family of 6 IGF binding proteins (IGFBPs). We investigated mRNA expre
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::e86e76d5ec3f42aee5ba6983859fc5ce
https://research.rug.nl/en/publications/d4ea0493-723e-49ae-84c7-07dde9500065
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6
Enhanced production and proteolytic degradation of insulin-like growth factor binding protein-2 in proliferating rat astrocytes
Autor: Chesik, D., Wilczak, N., De Keyser, Jacques, Kuhl, N.m.
Publikováno v: Journal of Neuroscience Research, 77(3), 354-362. Wiley-Blackwell
Insulin-like growth factors (IGFs) protect neurons, are important for oligodendrocyte survival and myelin production, and stimulate the proliferation of astrocytes. The effects of IGFs are regulated by a family of IGF binding proteins (IGFBPs). Astro
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::33749fe25347bc8e974a9143d00eb771
https://research.rug.nl/en/publications/c15977f6-6564-4e65-9529-37ff02351b1b
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7
Insulin-like growth factor (IGF)-I binding to a cell membrane associated IGF binding protein-3 acid-labile subunit complex in human anterior pituitary gland
Autor: Wilczak, N, Kuhl, N, Chesik, D, Geerts, A, Luiten, P, De Keyser, J
Publikováno v: J. Neurochemistry, 82(2), 430-438. Blackwell Publishing Ltd
Journal of Neurochemistry, 82(2), 430-438. Blackwell Publishing Ltd
The binding characteristics of [(125) I]insulin-like growth factor (IGF)-I were studied in human brain and pituitary gland. Competition binding studies with DES(1-3)IGF-I and R-3 -IGF-I, which display high affinity for the IGF-I receptor and low affi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::d1780843f5997678f513b20e6e131361
https://research.rug.nl/en/publications/35e69d8f-cec3-45c9-be2e-c0a1c81930be
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8
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