Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Cheryl Y. Brown"'
Autor:
Ying Y. Wong, Jessica E. Harbison, Christopher M. Hope, Batjargal Gundsambuu, Katherine A. Brown, Soon W. Wong, Cheryl Y Brown, Jennifer J. Couper, Jimmy Breen, Ning Liu, Stephen M. Pederson, Maren Köhne, Kathrin Klee, Joachim Schultze, Marc Beyer, Timothy Sadlon, Simon C. Barry
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract Epigenetic features such as DNA accessibility dictate transcriptional regulation in a cell type- and cell state- specific manner, and mapping this in health vs. disease in clinically relevant material is opening the door to new mechanistic i
Externí odkaz:
https://doaj.org/article/a56eda72cadc4472b5afe216794b04ff
Autor:
Cheryl Y. Brown, Timothy Sadlon, Christopher M. Hope, Ying Y. Wong, Soon Wong, Ning Liu, Holly Withers, Katherine Brown, Veronika Bandara, Batjargal Gundsambuu, Stephen Pederson, James Breen, Sarah Anne Robertson, Alistair Forrest, Marc Beyer, Simon Charles Barry
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
There has been much interest in the ability of regulatory T cells (Treg) to switch function in vivo, either as a result of genetic risk of disease or in response to environmental and metabolic cues. The relationship between levels of FOXP3 and functi
Externí odkaz:
https://doaj.org/article/6dbb30a28ff74c4f98b300019ce7d841
Autor:
G Ang, Timothy Sadlon, Batjargal Gundsambuu, Danika L. Hill, CM Hope, J Welch, Arunesh Mohandas, R Grosse, M Papadimetrios, Daniel J. Campbell, Stephen Pederson, JJ Couper, Thomas Duhen, Heddy Zola, Nicola Eastaff-Leung, Suzanne Bresatz, Simon C. Barry, Doreen Krumbiegel, Cheryl Y. Brown
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::006142a923921853db9ae841d01ed976
https://doi.org/10.1002/eji.201948094/v2/response1
https://doi.org/10.1002/eji.201948094/v2/response1
Autor:
John Welch, Heddy Zola, Simon C. Barry, Doreen Krumbiegel, Daniel J. Campbell, Timothy Sadlon, Batjargal Gundsambuu, Cheryl Y. Brown, Grace Ang, Stephen Pederson, Jennefer J Couper, Randall Grosse, Danika L. Hill, Nicola Eastaff-Leung, Christoper M Hope, Arunesh Mohandas, Michael Papademetrios, Suzanne Bresatz, Thomas Duhen
Publikováno v:
European journal of immunology. 49(8)
CD4+ T-cell subsets play a major role in the host response to infection, and a healthy immune system requires a fine balance between reactivity and tolerance. This balance is in part maintained by regulatory T cells (Treg), which promote tolerance, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f34e6e948e134f4822c90895c98b0dc1
https://pubmed.ncbi.nlm.nih.gov/31127857
https://pubmed.ncbi.nlm.nih.gov/31127857
Autor:
Katrina Ngui, Cheryl Y. Brown, Alexandra J. Roth-Schulze, Stephen Wilcox, Esther Bandala-Sanchez, John M. Wentworth, Leonard C. Harrison, Jennifer J Couper, Jocelyn Sietsma Penington, Anthony T. Papenfuss, Nadim J. Ajami, Joseph F. Petrosino, Simon C. Barry, Megan A. S. Penno
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-10 (2018)
Scientific Reports
Scientific Reports
To optimise fecal sampling for reproducible analysis of the gut microbiome, we compared different methods of sample collection and sequencing of 16S rRNA genes at two centers. Samples collected from six individuals on three consecutive days were plac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::760c5bbe8e0f326a060670a6e5d49226
https://doi.org/10.1038/s41598-018-22491-7
https://doi.org/10.1038/s41598-018-22491-7
Autor:
Cheryl Y. Brown, Alistair R. R. Forrest, James Breen, Simon C. Barry, Marc Beyer, Stephen Pederson, John E. Schjenken, Timothy Sadlon, Sarah A. Robertson, Veronika Bandara, Christopher M. Hope
Publikováno v:
Clinical & Translational Immunology 7(2), e1011 (2018). doi:10.1002/cti2.1011
Clinical & Translational Immunology
Clinical & Translational Immunology
Regulatory T cells (Treg) are critical for preventing autoimmunity and curtailing responses of conventional effector T cells (Tconv). The reprogramming of T‐cell fate and function to generate Treg requires switching on and off of key gene regulator
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5ca7131652a61175c11ec5733c8d103
https://pub.dzne.de/record/139880
https://pub.dzne.de/record/139880
Autor:
Soon Wei Wong, Stephen Pederson, Gregory J. Goodall, Timothy Sadlon, Cheryl Y. Brown, Christopher M. Hope, Darryl L. Russell, Adrian Kamil Kaczmarek, Victoria K Arnet, Sonia Dayan, Simon C. Barry
Publikováno v:
Oncotarget
Control of oncogenes, including ZEB1 and ZEB2, is a major checkpoint for preventing cancer, and loss of this control contributes to many cancers, including breast cancer. Thus tumour suppressors, such as FOXP3, which is mutated or lost in many cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11cd9d570633e9db2ac7bcf718c5995e
https://hdl.handle.net/11541.2/132885
https://hdl.handle.net/11541.2/132885
Autor:
Stephen Wilcox, Joseph F. Petrosino, Anthony T. Papenfuss, Jennifer J Couper, Jocelyn Sietsma Penington, Esther Bandala-Sanchez, John M. Wentworth, Cheryl Y. Brown, Simon C. Barry, Alexandra J. Roth-Schulze, Nadim J. Ajami, Katrina Ngui, Leonard C. Harrison, Megan A. S. Penno
BackgroundTo optimise fecal sampling and analysis yielding reproducible microbiome data, and gain further insight into sources of its variation, we compared different collection conditions and 16S rRNA gene sequencing protocols in two centers. Fecal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0df7e1eb36354de11629614c08f06a59
Autor:
Natasha McInnes, Danika L. Hill, Joyce Ruitenberg, Nicola Eastaff-Leung, Timothy Sadlon, Cheryl Y. Brown, Steve Pederson, Doreen Krumbiegel, Simon C. Barry, Suzanne Bresatz-Atkins, Noel L Warner
Publikováno v:
Immunology & Cell Biology. 90:812-821
Natural Regulatory T cells (Tregs) are defined by stable expression of the cell surface proteins CD4 and CD25, low surface expression of CD127 and expression of the transcription factor FOXP3. The contribution of Treg to the prevention of autoimmunit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5eb89bb199b22102ccf7da67b0bde867
https://doi.org/10.1038/icb.2012.18
https://doi.org/10.1038/icb.2012.18
Autor:
Kaimen Peng, Richard J D'Andrea, M. Frances Shannon, Suzanne Bresatz, Cheryl Y. Brown, Gary G. Glonek, Stephen Pederson, Heddy Zola, Elizabeth Melville, Tessa Gargett, Bridget Gabrielle Wilkinson, Gregory J. Goodall, Simon C. Barry, Timothy Sadlon
Publikováno v:
The Journal of Immunology. 185:1071-1081
The transcription factor FOXP3 is essential for the formation and function of regulatory T cells (Tregs), and Tregs are essential for maintaining immune homeostasis and tolerance. This is demonstrated by a lethal autoimmune defect in mice lacking Fox
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a1a94f9a3fed8e1e4d59a24ba89fce6
https://doi.org/10.4049/jimmunol.1000082
https://doi.org/10.4049/jimmunol.1000082