Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Cheryl R Hann"'
Autor:
Gavin W Roddy, Uttio Roy Chowdhury, Kjersten J Anderson, Tommy A Rinkoski, Cheryl R Hann, Vince A Chiodo, W Clay Smith, Michael P Fautsch
Publikováno v:
PLoS ONE, Vol 17, Iss 5, p e0269261 (2022)
Glaucoma is the leading cause of irreversible blindness worldwide. Therapies for glaucoma are directed toward reducing intraocular pressure (IOP), the leading risk factor and only reliable therapeutic target via topical medications or with procedural
Externí odkaz:
https://doaj.org/article/28159d2c3ef34ea09182ba1e114134c9
Autor:
Uttio Roy Chowdhury, Rachel A Kudgus, Tommy A Rinkoski, Bradley H Holman, Cindy K Bahler, Cheryl R Hann, Joel M Reid, Peter I Dosa, Michael P Fautsch
Publikováno v:
PLoS ONE, Vol 15, Iss 4, p e0231841 (2020)
Elevated intraocular pressure is the only treatable risk factor for glaucoma, an eye disease that is the leading cause of irreversible blindness worldwide. We have identified cromakalim prodrug 1 (CKLP1), a novel water-soluble ATP-sensitive potassium
Externí odkaz:
https://doaj.org/article/fa3ee5a25e0c4533837d93f3c27cfe39
Autor:
Timothy W. Olsen, MD, Collin G. Asheim, MD, Diva R. Salomao, MD, Cheryl R. Hann, Kathy Wabner, Jenn Schmit, RN, Amir Naqwi, PhD
Publikováno v:
Ophthalmology Science, Vol 3, Iss 3, Pp 100296- (2023)
Purpose: To determine the effectiveness of aerosol-delivered methotrexate (AD-MTx) in a large-animal (porcine) model of proliferative vitreoretinopathy (PVR). Design: Prospective, randomized, interventional, double-masked, controlled, large-animal st
Externí odkaz:
https://doaj.org/article/59a0443633b34f8791279684f2be8541
Evaluation of neural innervation in the human conventional outflow pathway distal to Schlemm's canal
Autor:
Cheryl R. Hann, Michael D. Bentley, Andrew Vercnocke, Uttio Roy Chowdhury, Michael P. Fautsch
Publikováno v:
Experimental eye research. 221
The distal outflow pathway of the human eye consists of the outer wall of Schlemm's canal, collector channels, and the deep-scleral, mid-scleral and episcleral vessels. It is the last region of transit for aqueous humor before returning to the venous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a06eebe142970b0f468b791bd4218c86
https://pubmed.ncbi.nlm.nih.gov/35636488
https://pubmed.ncbi.nlm.nih.gov/35636488
Autor:
Colin Andrew Bretz, Michael P. Fautsch, David Sheikh-Hamad, Alan D. Marmorstein, Lauren A Dalvin, Mary Elizabeth Hartnett, Gavin W. Roddy, Cheryl R. Hann, Ricky Z Cui
Publikováno v:
Curr Eye Res
PURPOSE/AIM: Abnormal activation of signaling pathways related to angiogenesis, inflammation, and oxidative stress has been implicated in the pathophysiology of retinopathy of prematurity (ROP), a leading cause of blindness in pre-term infants. Thera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a8ab5c1d7d7b156074284154681f3ef
https://doi.org/10.1080/02713683.2019.1645184
https://doi.org/10.1080/02713683.2019.1645184
Autor:
Michael P. Fautsch, Eric McCloud, Uttio Roy Chowdhury, Cheryl R. Hann, Bradley H. Holman, Cindy K. Bahler, Tommy A. Rinkoski, Peter I. Dosa, Joel M. Reid, Rachel A. Kudgus, Susan E. Appt
Publikováno v:
J Ocul Pharmacol Ther
Purpose: To evaluate pharmacokinetic parameters and ocular hypotensive effects of cromakalim prodrug 1 (CKLP1) in normotensive large animal models. Methods: Optimal CKLP1 concentration was determined by dose response and utilized in short- (5–8 day
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af3c997d03d0a608afeb32fe104b8458
https://pubmed.ncbi.nlm.nih.gov/33784195
https://pubmed.ncbi.nlm.nih.gov/33784195
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Scientific Reports
Scientific Reports
Ocular hypertension occurs due to increased resistance to aqueous humor removal through the conventional outflow pathway. Unlike the proximal region of the conventional outflow pathway, the distal region has not been well studied, mostly due to lack
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eba5fa522cecf52c909db68074239024
https://doi.org/10.1038/s41598-021-83558-6
https://doi.org/10.1038/s41598-021-83558-6
Autor:
Michael P. Fautsch, Bradley H. Holman, Kimberly Viker, Robert H. Rosa, Sophie J. Bakri, Anuradha Krishnan, Gavin W. Roddy, Gregory J. Gores, Cheryl R. Hann
Publikováno v:
Curr Eye Res
Introduction: Metabolic syndrome is a disorder characterized by a constellation of findings including truncal obesity, elevated blood pressure, abnormal cholesterol levels, and high blood glucose. Recent evidence suggests that metabolic syndrome may
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d7a8dd4a17a20a577198066cc8af637
https://europepmc.org/articles/PMC7239759/
https://europepmc.org/articles/PMC7239759/
Autor:
Tommy A. Rinkoski, Cheryl R. Hann, Uttio Roy Chowdhury, Michael P. Fautsch, Peter I. Dosa, Bradley H. Holman, Joel M. Reid, Rachel A. Kudgus, Cindy K. Bahler
Publikováno v:
PLoS ONE, Vol 15, Iss 4, p e0231841 (2020)
PLoS ONE
PLoS ONE
Elevated intraocular pressure is the only treatable risk factor for glaucoma, an eye disease that is the leading cause of irreversible blindness worldwide. We have identified cromakalim prodrug 1 (CKLP1), a novel water-soluble ATP-sensitive potassium
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a7b32aab089ea75a322fad5b3d1b586
https://doi.org/10.1371/journal.pone.0231841
https://doi.org/10.1371/journal.pone.0231841
Autor:
Cheryl R. Hann, David Haffner, Michael P. Fautsch, Hal Heitzmann, Todd Fjield, Cindy K. Bahler
Publikováno v:
American Journal of Ophthalmology. 153:1206-1213
To determine whether a second-generation trabecular meshwork (TM) bypass stent (iStent inject) influences outflow facility in cultured human anterior segments.Prospective laboratory investigation using normal human donor eyes.Human anterior segments
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aafc936d214279d882a035a102af8d6d
https://doi.org/10.1016/j.ajo.2011.12.017
https://doi.org/10.1016/j.ajo.2011.12.017