Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Cheryl P. Mugford"'
Autor:
Reinhardt Bernhard Baudy, Boyd L. Harrison, Jean Y. Sze, Menelas N. Pangalos, Jeffrey D. Kennedy, Michael R. Brandt, Michael May, Terri Cummons, Ronald L. Magolda, Wayne E. Childers, Uday Jain, John A. Butera, Matthew Hoffmann, Hong Chen, Diane Kowal, Bojana Zupan, Magid Abou-Gharbia, Cheryl P. Mugford
Publikováno v:
Journal of medicinal chemistry. 52(3)
Previous studies with perzinfotel (1), a potent, selective, competitive NMDA receptor antagonist, showed it to be efficacious in inflammatory and neuropathic pain models. To increase the low oral bioavailability of 1 (3−5%), prodrug derivatives (3a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dc47d6ea6774cab53f633c680537098
https://pubmed.ncbi.nlm.nih.gov/19146418
https://pubmed.ncbi.nlm.nih.gov/19146418
Autor:
Girija Krishnamurthy, David L. Crandall, Hassan Mahmoud Elokdah, Geraldine Ruth Mcfarlane, Cheryl P. Mugford, James Hennan, Magid Abou-Gharbia
Publikováno v:
ChemInform. 35
Indole oxoacetic acid derivatives were prepared and evaluated for in vitro binding to and inactivation of human plasminogen activator inhibitor-1 (PAI-1). SAR based on biochemical, physiological, and pharmacokinetic attributes led to identification o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4440dfe10c7270a591fdfcb514afcc40
https://doi.org/10.1002/chin.200442134
https://doi.org/10.1002/chin.200442134
Autor:
Puwen Zhang, Eugene A. Terefenko, Jenifer Bray, Darlene Deecher, Andrew Fensome, Jim Harrison, Callain Kim, Elizabeth Koury, Lilly Mark, Casey C. McComas, Cheryl A. Mugford, Eugene J. Trybulski, An T. Vu, Garth T. Whiteside, Paige E. Mahaney
Publikováno v:
Journal of Medicinal Chemistry; Sep2009, Vol. 52 Issue 18, p5703-5711, 9p
Autor:
Paige E. Mahaney, Lori K. Gavrin, Eugene J. Trybulski, Gary P. Stack, An T. Vu, Stephen T. Cohn, Fei Ye, Justin K. Belardi, Arthur A. Santilli, Joseph P. Sabatucci, Jennifer Leiter, Grace H. Johnston, Jenifer A. Bray, Kevin D. Burroughs, Scott A. Cosmi, Liza Leventhal, Elizabeth J. Koury, Yingru Zhang, Cheryl A. Mugford, Douglas M. Ho
Publikováno v:
Journal of Medicinal Chemistry; Jun2008, Vol. 51 Issue 13, p4038-4049, 12p
Autor:
Andrew Fensome, William R. Adams, Andrea L. Adams, Tom J. Berrodin, Jeff Cohen, Christine Huselton, Arthur Illenberger, Jeffrey C. Kern, Valerie A. Hudak, Michael A. Marella, Edward G. Melenski, Casey C. McComas, Cheryl A. Mugford, Ov D. Slayden, Matthew Yudt, Zhiming Zhang, Puwen Zhang, Yuan Zhu, Richard C. Winneker, Jay E. Wrobel
Publikováno v:
Journal of Medicinal Chemistry; Feb2008, Vol. 51 Issue 6, p1861-1873, 13p