Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Cheryl P Ewing"'
Autor:
Mario A Monteiro, Yu-Han Chen, Zuchao Ma, Cheryl P Ewing, Nooraisyah Mohamad Nor, Eman Omari, Ellen Song, Pawel Gabryelski, Patricia Guerry, Frédéric Poly
Publikováno v:
PLoS ONE, Vol 16, Iss 2, p e0247305 (2021)
The Campylobacter jejuni capsule type HS1 complex is one of the most common serotypes identified worldwide, and consists of strains typing as HS1, HS1/44, HS44 and HS1/8. The capsule structure of the HS1 type strain was shown previously to be compose
Externí odkaz:
https://doaj.org/article/c1392dfb4e2342af911029d56efae0da
Publikováno v:
Proceedings of the National Academy of Sciences. 117:16985-16991
Vertebrates, from zebra fish to humans, have an innate immune recognition of many bacterial flagellins. This involves a conserved eight-amino acid epitope in flagellin recognized by the Toll-like receptor 5 (TLR5). Several important human pathogens,
Autor:
Steven T. Poole, Yang Liu, Patricia Guerry, Renee M. Laird, Eman Omari, Frédéric Poly, Annette L. McVeigh, Nelum Dorabawila, Kavyashree Satish, Mario A. Monteiro, Milton Maciel, Cheryl P. Ewing, Brittany Pequegnat, Nina M. Schumack, Zuchao Ma, Alexander C. Maue, Christina L. Gariepy, Michael G. Prouty, Stephen J. Savarino
Publikováno v:
Vaccine. 36:6695-6702
Enterotoxigenic Escherichia coli (ETEC), Campylobacter jejuni (CJ), and Shigella sp. are major causes of bacterial diarrhea worldwide, but there are no licensed vaccines against any of these pathogens. Most current approaches to ETEC vaccines are bas
Autor:
Frédéric Poly, Mario A. Monteiro, Yu-Han Chen, Zuchao Ma, Cheryl P. Ewing, Pawel Gabryelski, Eman Omari, Nooraisyah Mohamad Nor, Patricia Guerry, Ellen Song
Publikováno v:
PLoS ONE, Vol 16, Iss 2, p e0247305 (2021)
PLoS ONE
PLoS ONE
The Campylobacter jejuni capsule type HS1 complex is one of the most common serotypes identified worldwide, and consists of strains typing as HS1, HS1/44, HS44 and HS1/8. The capsule structure of the HS1 type strain was shown previously to be compose
Autor:
Bryan William Davies, Patricia Guerry, David A. Sack, Joanna E. Rimmer, Mark S. Riddle, Clayton Harro, Cheryl P. Ewing, David R. Tribble, Kawsar R. Talaat, Kayla Jaep, M. Stephen Trent, Frédéric Poly, Alexander C. Maue, Ashley Alcala, Amritha Ramakrishnan, Jessica Brubaker, Ramiro L. Gutierrez, Barbara DeNearing, Alexander A. Crofts, Chad K. Porter, Renee M. Laird, Andrea J. McCoy, Janelle Kuroiwa
Publikováno v:
Nature Microbiology. 3:494-502
Campylobacter jejuni infections are a leading cause of bacterial food-borne diarrhoeal illness worldwide, and Campylobacter infections in children are associated with stunted growth and therefore long-term deficits into adulthood. Despite this global
Autor:
Patricia Guerry, Mario A. Monteiro, Christina L Hill, Cheryl P. Ewing, Brittany Pequegnat, Renee M. Laird, Eman Omari, Frédéric Poly
Publikováno v:
Journal of Bacteriology. 199
Campylobacter jejuni polysaccharide capsules (CPS) are characterized by the presence of nonstoichiometric O -methyl phosphoramidate (MeOPN) modifications. The lack of stoichiometry is due to phase variation at homopolymeric tracts within the MeOPN tr
Autor:
Lisa Bertolo, Patricia Guerry, Cheryl P. Ewing, Mario A. Monteiro, Frédéric Poly, Alexander Maue
Publikováno v:
Carbohydrate Research. 366:45-49
Campylobacter jejuni infection is now the main cause of diarrhea-related illnesses in humans. An efficacious vaccine for the traveler and developing world market would be welcomed. We are engaged in the discovery and characterization of serotype-spec
Publikováno v:
Journal of Bacteriology. 191:7086-7093
The major flagellin of Campylobacter jejuni strain 81-176, FlaA, has been shown to be glycosylated at 19 serine or threonine sites, and this glycosylation is required for flagellar filament formation. Some enzymatic components of the glycosylation ma
Publikováno v:
Journal of Molecular Biology. 384:364-376
Campylobacter jejuni, a Gram-negative motile bacterium, is a leading cause of human gastrointestinal infections. Although the mechanism of C.jejuni-mediated enteritis appears to be multifactorial, flagella play complex roles in the virulence of this
Publikováno v:
Carbohydrate research. 418
Campylobacter jejuni is a leading cause of traveler's diarrhea. Previously, we have shown that a C. jejuni capsule polysaccharide (CPS) conjugate vaccine can fully prevent C.jejuni diarrhea in non-human primates. C.jejuni CPSs are decorated with non-