Zobrazeno 1 - 10
of 221
pro vyhledávání: '"Cheryl M, Coffin"'
Publikováno v:
Human Pathology: Case Reports, Vol 22, Iss , Pp 200434- (2020)
Since the discovery of the ETV6-NTRK3 gene fusion in infantile fibrosarcoma two decades ago, it has become an important diagnostic marker because it is found in the majority of cases. However, the development of new molecular tests, including next ge
Externí odkaz:
https://doaj.org/article/7e38d56c477443c48ea4b44692cf3cfc
Autor:
Jennifer O. Black, Alyaa Al-Ibraheemi, Michael A. Arnold, Cheryl M. Coffin, Jessica L. Davis, David M. Parham, Erin R. Rudzinski, Archana Shenoy, Lea F. Surrey, Serena Y. Tan, Sheri L. Spunt
Publikováno v:
Archives of Pathology & Laboratory Medicine.
Context.— Pediatric soft tissue tumors are one of the areas of pediatric pathology that frequently generate consult requests. Evolving classification systems, ancillary testing methods, new treatment options, research enrollment opportunities, and
Autor:
Cheryl M. Coffin, Vincent A. Miller, Philip J. Stephens, Jeffrey S. Ross, Scott C. Borinstein, Catherine T. Chung, Tina Brennan, Geoff Otto, Doron Lipson, Abha Gupta, Christine M. Lovly
Inflammatory myofibroblastic tumor (IMT) is a neoplasm that typically occurs in children. The genetic landscape of this tumor is incompletely understood and therapeutic options are limited. Although 50% of IMTs harbor anaplastic lymphoma kinase (ALK)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07be273dff28707890280a3bebc93ed1
https://doi.org/10.1158/2159-8290.c.6546131
https://doi.org/10.1158/2159-8290.c.6546131
Autor:
Cheryl M. Coffin, Vincent A. Miller, Philip J. Stephens, Jeffrey S. Ross, Scott C. Borinstein, Catherine T. Chung, Tina Brennan, Geoff Otto, Doron Lipson, Abha Gupta, Christine M. Lovly
PDF file - 106KB, Schematic representation of the study design. 37 IMT tumor samples from 33 patients were collected under IRB approved protocols. ALK immunohistochemistry (IHC) was performed on each of the 37 cases as standard of clinical care. Targ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::310b60223bfdf22fe03b4265ac418c03
https://doi.org/10.1158/2159-8290.22530230.v1
https://doi.org/10.1158/2159-8290.22530230.v1
Autor:
Cheryl M. Coffin, Vincent A. Miller, Philip J. Stephens, Jeffrey S. Ross, Scott C. Borinstein, Catherine T. Chung, Tina Brennan, Geoff Otto, Doron Lipson, Abha Gupta, Christine M. Lovly
PDF file - 77KB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e99c9f545bf5b5a5ee997103b702c3af
https://doi.org/10.1158/2159-8290.22530227.v1
https://doi.org/10.1158/2159-8290.22530227.v1
Autor:
Cheryl M. Coffin, Vincent A. Miller, Philip J. Stephens, Jeffrey S. Ross, Scott C. Borinstein, Catherine T. Chung, Tina Brennan, Geoff Otto, Doron Lipson, Abha Gupta, Christine M. Lovly
PDF file - 71KB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3d97914d46f6d817fa6f69ff5f786ed
https://doi.org/10.1158/2159-8290.22530224.v1
https://doi.org/10.1158/2159-8290.22530224.v1
Autor:
Cheryl M. Coffin, Vincent A. Miller, Philip J. Stephens, Jeffrey S. Ross, Scott C. Borinstein, Catherine T. Chung, Tina Brennan, Geoff Otto, Doron Lipson, Abha Gupta, Christine M. Lovly
PDF file - 59KB, Schematic representation of the index patient's treatment history. A timeline detailing the index patient's diagnosis and subsequent systemic therapies is depicted. Time in months is shown below the arrow. The timeline starts at the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8475e91e3bea221dfeafee474d189edb
https://doi.org/10.1158/2159-8290.22530233.v1
https://doi.org/10.1158/2159-8290.22530233.v1
Autor:
Cheryl M. Coffin, Vincent A. Miller, Philip J. Stephens, Jeffrey S. Ross, Scott C. Borinstein, Catherine T. Chung, Tina Brennan, Geoff Otto, Doron Lipson, Abha Gupta, Christine M. Lovly
PDF file - 137KB, Summary of genomic coordinates for the kinase fusions identified in this study. The sample number is depicted in the far left column. For tumor samples in which a kinase fusion was identified, the genomic coordinates for of each of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad107a89246261d19fd156b255dcec22
https://doi.org/10.1158/2159-8290.22530215
https://doi.org/10.1158/2159-8290.22530215
Autor:
Cheryl M. Coffin, Vincent A. Miller, Philip J. Stephens, Jeffrey S. Ross, Scott C. Borinstein, Catherine T. Chung, Tina Brennan, Geoff Otto, Doron Lipson, Abha Gupta, Christine M. Lovly
PDF file - 53KB, FoundationOne panel. This targeted next generation sequencing platform evaluates for 3769 exons of 236 cancer genes and 47 introns of 19 commonly rearranged genes, including 8 tyrosine kinases.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09c38bd160d0d6da6f8c515f7d599511
https://doi.org/10.1158/2159-8290.22530218.v1
https://doi.org/10.1158/2159-8290.22530218.v1
Autor:
Cheryl M. Coffin, Vincent A. Miller, Philip J. Stephens, Jeffrey S. Ross, Scott C. Borinstein, Catherine T. Chung, Tina Brennan, Geoff Otto, Doron Lipson, Abha Gupta, Christine M. Lovly
PDF file - 87KB, Changes in the indicated laboratory parameters after 3 cycles of crizotinib. HgB: hemoglobin, Hct: hematocrit, MCV: mean corpuscular volume, ESR: erythrocyte sedimentation rate, LDH: lactate dehydrogenase.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fdc76531dea7fbe23a603f16375ca30
https://doi.org/10.1158/2159-8290.22530221.v1
https://doi.org/10.1158/2159-8290.22530221.v1