Zobrazeno 1 - 10 of 14 pro vyhledávání: '"Cheryl London"'
1
Akademický článek
A CTSA One Health Alliance (COHA) survey of clinical trial infrastructure in North American veterinary institutions
Autor: Sarah A. Moore, Angela McCleary-Wheeler, Joan R Coates, Natasha Olby, Cheryl London
Publikováno v: BMC Veterinary Research, Vol 17, Iss 1, Pp 1-8 (2021)
Abstract While a necessary step toward enhancing rigor and reproducibility of veterinary clinical trials conducted on the translational spectrum includes understanding the current state of the field, no broad assessment of existing veterinary clinica
Externí odkaz: https://doaj.org/article/6b5f1e2cef0149c5ba4d23bbdcd12065
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2
Akademický článek
Classical NF-κB Metabolically Reprograms Sarcoma Cells Through Regulation of Hexokinase 2
Autor: Priya Londhe, Peter Y. Yu, Yuichi Ijiri, Katherine J. Ladner, Joelle M. Fenger, Cheryl London, Peter J. Houghton, Denis C. Guttridge
Publikováno v: Frontiers in Oncology, Vol 8 (2018)
BackgroundMetabolic reprogramming has emerged as a cancer hallmark, and one of the well-known cancer-associated metabolic alterations is the increase in the rate of glycolysis. Recent reports have shown that both the classical and alternative signali
Externí odkaz: https://doaj.org/article/454ae91c45e04e6990122e03d8a55e95
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3
Akademický článek
Comparison of harmonic blade versus traditional approach in canine patients undergoing spinal decompressive surgery for naturally occurring thoracolumbar disk extrusion.
Autor: Bianca F Hettlich, Laurie Cook, Cheryl London, Geoffrey T Fosgate
Publikováno v: PLoS ONE, Vol 12, Iss 3, p e0172822 (2017)
OBJECTIVES:To assess feasibility of the harmonic Osteovue blade (HOB) for use in the soft tissue approach for dogs undergoing hemilaminectomy and to compare outcomes between dogs undergoing HOB or traditional approach (TRAD). METHODS:A prospective ra
Externí odkaz: https://doaj.org/article/1109fdd7a01f44d6bc5a582d8c8dd3da
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4
Akademický článek
Genome-Wide Association Study of Golden Retrievers Identifies Germ-Line Risk Factors Predisposing to Mast Cell Tumours.
Autor: Maja L Arendt, Malin Melin, Noriko Tonomura, Michele Koltookian, Celine Courtay-Cahen, Netty Flindall, Joyce Bass, Kim Boerkamp, Katherine Megquir, Lisa Youell, Sue Murphy, Colleen McCarthy, Cheryl London, Gerard R Rutteman, Mike Starkey, Kerstin Lindblad-Toh
Publikováno v: PLoS Genetics, Vol 11, Iss 11, p e1005647 (2015)
Canine mast cell tumours (CMCT) are one of the most common skin tumours in dogs with a major impact on canine health. Certain breeds have a higher risk of developing mast cell tumours, suggesting that underlying predisposing germ-line genetic factors
Externí odkaz: https://doaj.org/article/895b2898a7834518bb77388c3398301a
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5
Data from The Bromodomain BET Inhibitor JQ1 Suppresses Tumor Angiogenesis in Models of Childhood Sarcoma
Autor: Peter J. Houghton, Xiaokui Mo, Laurence H. Baker, Cheryl London, Jiayuh Lin, Denis C. Guttridge, Linlin Xaio, Doris A. Phelps, Hemant K. Bid
The bromodomain and extra-terminal domain inhibitor JQ1 has marked antitumor activity against several hematologic malignancies as well as solid tumor models. Here, we investigated its activity in vitro and in vivo against models of childhood rhabdomy
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::eba441bdabcac029dcfc62a1a92da2d8
https://doi.org/10.1158/1535-7163.c.6538732.v1
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6
Supplemental Figure Legends and Figures 1-7 from The Bromodomain BET Inhibitor JQ1 Suppresses Tumor Angiogenesis in Models of Childhood Sarcoma
Autor: Peter J. Houghton, Xiaokui Mo, Laurence H. Baker, Cheryl London, Jiayuh Lin, Denis C. Guttridge, Linlin Xaio, Doris A. Phelps, Hemant K. Bid
Supplemental Figure Legends; Supplemental Figure 1. JQ1 induces G1 accumulation without enhancing the sub-G1 population in sensitive sarcoma cell lines. Cells were exposed for 24 Hr to 500 nM JQ1; Supplemental Figure 2. Quantitation of immunoblots fr
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d95d0e38b8e93962710e99c685718a1
https://doi.org/10.1158/1535-7163.22507591.v1
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10
Abstract 46: High-plex spatial transcriptomic characterization of canine tumor tissue
Autor: Sarah E. Church, Cheryl London, Christine M. Toedebusch, Ben Sutton, Sarah Weigel, Erin Piazza
Publikováno v: Cancer Research. 83:46-46
Background: Combination therapy to treat hematological and solid malignancies including chemotherapy, radiation, targeted and immunotherapy all hold huge potential for eliciting clinical responses. Informative pre-clinical testing of these approaches
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a87f485935ec7e4348c9022ce7cc621f
https://doi.org/10.1158/1538-7445.am2023-46
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