Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Cheryl L Sershen"'
Publikováno v:
Frontiers in Systems Biology, Vol 3 (2023)
Recent research has shown that people who suffer from chronic obstructive pulmonary disease (COPD) have a greater propensity to contract and develop tuberculosis (TB) than the general population. Not only is the hazard ratio for contracting active tu
Externí odkaz:
https://doaj.org/article/cbf76f0afc21402bb9a5f1b5789c5101
Autor:
Metin Akay, Yong Du, Cheryl L. Sershen, Minghua Wu, Ting Y. Chen, Shervin Assassi, Chandra Mohan, Yasemin M. Akay
Publikováno v:
IEEE Open Journal of Engineering in Medicine and Biology, Vol 2, Pp 104-110 (2021)
Goal: Systemic sclerosis (SSc) is a rare autoimmune, systemic disease with prominent fibrosis of skin and internal organs. Early diagnosis of the disease is crucial for designing effective therapy and management plans. Machine learning algorithms, es
Externí odkaz:
https://doaj.org/article/7bd60bd0e0e0465a8d1484c4b7211077
Autor:
Yong Du, Ting Y. Chen, Minghua Wu, Cheryl L. Sershen, Yasemin M. Akay, Shervin Assassi, Metin Akay, Chandra Mohan
Publikováno v:
IEEE Open Journal of Engineering in Medicine and Biology, Vol 2, Pp 104-110 (2021)
Goal: Systemic sclerosis (SSc) is a rare autoimmune, systemic disease with prominent fibrosis of skin and internal organs. Early diagnosis of the disease is crucial for designing effective therapy and management plans. Machine learning algorithms, es
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef92056a273cf86b71e31aa053ec5bcf
https://ieeexplore.ieee.org/document/9380371/
https://ieeexplore.ieee.org/document/9380371/
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 6 (2016)
In several mammalian hosts, including non-human primates, Mycobacterium tuberculosis granulomas are often hypoxic, although this has not been observed in wild type murine infection models. Mtb associated granuloma formation can be viewed as a structu
Externí odkaz:
https://doaj.org/article/d6dcbf1425254aaabf19af919cffc7b0
Publikováno v:
PLoS ONE, Vol 11, Iss 6, p e0153289 (2016)
Macrophage produced inducible nitric oxide synthase (iNOS) is known to play a critical role in the proinflammatory response against intracellular pathogens by promoting the generation of bactericidal reactive nitrogen species. Robust and timely produ
Externí odkaz:
https://doaj.org/article/55e50c7b93294359be417836ef7d297e
Autor:
Cheryl L. Sershen
Publikováno v:
Journal of Applied Mathematics and Computation. 4:43-56
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8470a109f86e189d481b3cd49e6db7ba
https://doi.org/10.26855/jamc.2020.09.001
https://doi.org/10.26855/jamc.2020.09.001
Publikováno v:
PLoS ONE, Vol 6, Iss 6, p e20798 (2011)
The susceptibility to recombination of a plasmid inserted into a chromosome varies with its genomic position. This recombination position effect is known to correlate with the average G+C content of the flanking sequences. Here we propose that this e
Externí odkaz:
https://doaj.org/article/5ced6847cbdf456f8ac9859f562f0f23
Autor:
Cheryl L. Sershen, Elebeoba E. May
Publikováno v:
IEEE Transactions on Biomedical Engineering. 63:2036-2046
Objective: In vitro models of Mycobacterium tuberculosis (Mtb) nonreplicating persistence (NRP) suggest the rate of oxygen ( $O_2$ ) depletion is a significant determinant in persistence. However, few studies have characterized the metabolic associat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::279b77432720db2b784dcce653f15daf
https://doi.org/10.1109/tbme.2016.2605701
https://doi.org/10.1109/tbme.2016.2605701
Publikováno v:
Frontiers in Cellular and Infection Microbiology
Frontiers in Cellular and Infection Microbiology, Vol 6 (2016)
Frontiers in Cellular and Infection Microbiology, Vol 6 (2016)
Mycobacterium tuberculosis associated granuloma formation can be viewed as a structural immune response that can contain and halt the spread of the pathogen. In several mammalian hosts, including non-human primates, Mtb granulomas are often hypoxic,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a86376f4b29a1e79d1f258653ac485f5
https://pubmed.ncbi.nlm.nih.gov/26913242
https://pubmed.ncbi.nlm.nih.gov/26913242
Publikováno v:
EMBC
This paper describes a method for incorporating a diffusion field modeling oxygen usage and dispersion in a multi-scale model of Mycobacterium tuberculosis (Mtb) infection mediated granuloma formation. We implemented this method over a floating-point
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42f954981cf4ef539e77b35aba1b0cf4
https://doi.org/10.1109/embc.2014.6943590
https://doi.org/10.1109/embc.2014.6943590