Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Cheryl L Fattman"'
Autor:
David M Brass, Jennifer C Spencer, Zhuowei Li, Erin Potts-Kant, Sarah M Reilly, Mary K Dunkel, Joseph D Latoche, Richard L Auten, John W Hollingsworth, Cheryl L Fattman
Publikováno v:
PLoS ONE, Vol 11, Iss 5, p e0155388 (2016)
Externí odkaz:
https://doaj.org/article/0b05956ffc1442ffb2ac78ad53d73116
Autor:
David M Brass, Jennifer C Spencer, Zhuowei Li, Erin Potts-Kant, Sarah M Reilly, Mary K Dunkel, Joseph D Latoche, Richard L Auten, John W Hollingsworth, Cheryl L Fattman
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e40789 (2012)
Acute exacerbations of pulmonary fibrosis are characterized by rapid decrements in lung function. Environmental factors that may contribute to acute exacerbations remain poorly understood. We have previously demonstrated that exposure to inhaled lipo
Externí odkaz:
https://doaj.org/article/944e9cfd89324a5d890ad7fdf995e062
Autor:
Lasse Ramsgaard, Judson M Englert, Jacob Tobolewski, Lauren Tomai, Cheryl L Fattman, Adriana S Leme, A Murat Kaynar, Steven D Shapiro, Jan J Enghild, Tim D Oury
Publikováno v:
PLoS ONE, Vol 5, Iss 3, p e9604 (2010)
The role of the receptor for advanced glycation end-products (RAGE) has been shown to differ in two different mouse models of asbestos and bleomycin induced pulmonary fibrosis. RAGE knockout (KO) mice get worse fibrosis when challenged with asbestos,
Externí odkaz:
https://doaj.org/article/f9ea7150ecf74b3b8bdd7545c3dcea4a
Autor:
Joseph D. Latoche, Cheryl L. Fattman, Koustav Ganguly, George D. Leikauf, Alexander Chukwuma Ufelle, Fabrizio Fazzi
Publikováno v:
Environmental Health Perspectives
Background: Fibrotic lung diseases occur predominantly in males, and reports describe better survival in affected females. Male mice are more sensitive to silica-induced lung fibrosis than silica-treated female mice. Secreted phosphoprotein 1 (SPP1,
Autor:
Cheryl L. Fattman, Jay K. Kolls, John F. Alcorn, Erich V. Scheller, Richard I. Enelow, Kevin J. McHugh, Derek Pociask, Sivanarayana Mandalapu
Publikováno v:
The American Journal of Pathology. 182(4):1286-1296
Influenza infection is widespread in the United States and the world. Despite low mortality rates due to infection, morbidity is common and little is known about the molecular events involved in recovery. Influenza infection results in persistent dis
Autor:
Leah Cambal, Jane E. Clougherty, Cheryl L. Fattman, Steven E. Mischler, Courtney Roper, Brett Tunno, Lauren Chubb
Publikováno v:
Water, Air, & Soil Pollution. 228
Filter-based toxicology studies are conducted to establish the biological plausibility of the well-established health impacts associated with fine particulate matter (PM2.5) exposure. Ambient PM2.5 collected on filters is extracted into solution for
Autor:
Kurt R. Stenmark, Susan M. Majka, Zachary Van Rheen, Cheryl L. Fattman, Dwight J. Klemm, Eva Nozik-Grayck, Shannon Domarski
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 44:500-508
Interstitial lung disease is a devastating disease in humans that can be further complicated by the development of secondary pulmonary hypertension. Accumulating evidence indicates that the oxidant superoxide can contribute to the pathogenesis of bot
Publikováno v:
Journal of Environmental Pathology, Toxicology and Oncology. 28:153-162
We tested the postulate that asbestos exposure alters iron homeostasis in the mouse lung. Crocidolite asbestos (100 microg intratracheally) was instilled into C57BL/6 mice. TiO2 served as a control exposure. Using iron staining and immunohistochemist
Autor:
Lana E. Hanford, Michael Kasper, Thomas J. Richards, Lasse Ramsgaard, Roderick J. Tan, Angelika Bierhaus, Judson M. Englert, Naftali Kaminski, Peter P. Nawroth, Tim D. Oury, Jacob M. Tobolewski, Cheryl L. Fattman, Inna Loutaev
Publikováno v:
The American Journal of Pathology. 172:583-591
Idiopathic pulmonary fibrosis (IPF) is a severely debilitating disease associated with a dismal prognosis. There are currently no effective therapies for IPF, thus the identification of novel therapeutic targets is greatly needed. The receptor for ad
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 294:L572-L581
Matrix metalloproteinases (MMPs) are mediators of lung injury, and their activity has been associated with the development of pulmonary fibrosis. To understand how MMPs regulate the development of pulmonary fibrosis, we examined MMP expression in two