Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Cheryl K. Lapham"'
Autor:
Rolf E. Taffs, Cheryl K. Lapham, Jody Manischewitz, Marina Zaitseva, Hana Golding, Tatiana Romantseva, Shirley Lee, Lisa King
Publikováno v:
Blood. 96:3109-3117
The effect of interferon γ (IFN-γ) and interleukin 6 (IL-6) on infection of macrophages with human immunodeficiency virus type 1 (HIV-1) was investigated. By using a polymerase chain reaction–based viral entry assay and viral infectivity assay, i
Autor:
Hong Chen, Hana Golding, Tzanko S. Stantchev, Lisa King, Howard Mostowski, Christopher C. Broder, Shirley Lee, Tatiana Romantseva, Jody Manischewitz, Cheryl K. Lapham
Publikováno v:
Journal of Virology. 74:5016-5023
Most of the cells that were found to be targets for human immunodeficiency virus (HIV) infection in vivo (i.e., T cells, macrophages, and dendritic cells) express both CD4 and multiple chemokine receptors. Among the chemokine receptors that were show
Autor:
Christopher C. Broder, Hana Golding, Marina Zaitseva, Cheryl K. Lapham, Dimiter S. Dimitrov, Jun Ouyang
Publikováno v:
AIDS Research and Human Retroviruses. 15:149-159
CD4-specific monoclonal antibodies (CG1, CG7, and CG8), which bind with a 5- to 10-fold higher avidity to preformed CD4-gp120 complexes than to CD4, were previously shown to recognize newly identified conformational epitopes in the D1-CDR3 region of
Autor:
Dimiter S. Dimitrov, Cheryl K. Lapham, Bhaskar Chandrasekhar, Hana Golding, Nga Yen Nguyen, Jun Ouyang
Publikováno v:
Science. 274:602-605
Accessory cell-surface molecules involved in the entry of human immunodeficiency virus-type 1 into cells have recently been identified and shown to belong to the family of chemokine receptors. Treatment of human cell lines with soluble monomeric gp12
Autor:
P Highet, J Inman, R Blackburn, Basil Golding, Cheryl K. Lapham, Jody Manischewitz, Hana Golding
Publikováno v:
Journal of Virology. 70:3084-3092
We have previously shown that immunization of mice with human immunodeficiency virus (HIV)-derived proteins or peptides conjugated to inactivated Brucella abortus induces the secretion of virus-neutralizing antibodies, predominantly of the immunoglob
Autor:
Cheryl K, Lapham, Tatiana, Romantseva, Emmanuel, Petricoin, Lisa R, King, Jody, Manischewitz, Marina B, Zaitseva, Hana, Golding
Publikováno v:
Journal of leukocyte biology. 72(6)
The chemokine receptor CXCR4 is a primary coreceptor for the HIV-1 virus. The predicted molecular weight (MW) of glycosylated CXCR4 is 45-47 kDa. However, immunoblots of whole cell lysates from human lymphocytes, monocytes, macrophages, and the Jurka
Publikováno v:
Nature medicine. 5(3)
Human macrophages can be infected more efficiently by M-tropic than by T-tropic HIV-1 strains, despite surface expression of both CXCR4 and CCR5 co-receptors. Western blot analyses of total cell extracts and surface proteins from multiple sets of mon
Autor:
Shirley Lee, Howard Mostowski, Hana Golding, Jody Manischewitz, Marina Zaitseva, Cheryl K. Lapham, Andrew Blauvelt, V Klaus-Kovtun
Publikováno v:
Nature medicine. 3(12)
Transmission of HIV-1 is predominantly restricted to macrophage (Mphi)-tropic strains. Langerhans cells (LCs) in mucosal epithelium, as well as macrophages located in the submucosal tissues, may be initial targets for HIV-1. This study was designed t
Autor:
Martin A. R. Yuille, Friedrich G. Petermann, Leonard V. Sacks, Cheryl K. Lapham, Russell H. Tomar, Patricia A. John
Publikováno v:
The Journal of infectious diseases. 164(3)
Natural killer (NK) activity in peripheral blood mononuclear cells is augmented by products released by two different strains of streptococci. This property is due at least in part to an erythrogenic toxin (ET). A preparation of physiologically activ
Publikováno v:
Cellular Immunology. 69:388-394
Streptokinase-streptodornase (SK-SD), a product of Group A and Group C β-hemolytic streptococci, activates natural killer (NK) cells in vitro. This effect appears to occur without the induction of interferon. It is not present in every individual bu