Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Cheryl F. Murphy"'
Autor:
James W. Patterson, Cheryl F. Murphy, Craig L. Slingluff, Kerrington R. Molhoek, J K Rasamny, Gulsun Erdag, David L. Brautigan, Donna H. Deacon
Publikováno v:
International Journal of Cancer. 129:2807-2815
Vascular endothelial growth factor (VEGF) is an angiogenic factor that also functions as an autocrine growth factor for VEGF receptor (VEGFR)-2(+) melanomas. In multiple studies, VEGFR-2 was detected by immunostaining in 78-89% of human melanoma cell
Autor:
Walter C. Olson, Scott A. Boerner, Kimberly A. Chianese-Bullock, Carmel J. Nail, Elizabeth J. Coleman, Cheryl F. Murphy, Mark E. Smolkin, Kevin T. Hogan, William P. Irvin, Patrice Y. Neese, Arlene Yuan, Craig L. Slingluff, Gina R. Petroni
Publikováno v:
Journal of Immunotherapy. 31:420-430
Nine participants with epithelial ovarian, fallopian tube, or primary peritoneal carcinoma, who were human leukocyte antigen (HLA)-A1, HLA-A2, or HLA-A3, were eligible to enroll in a phase 1 study designed to assess the safety and immunogenicity of a
Autor:
Patrice K. Rehm, William W. Grosh, Galina V. Yamshchikov, Cheryl F. Murphy, Mark E. Smolkin, Kimberly A. Chianese-Bullock, Craig L. Slingluff, Patrice Y. Neese, Gina R. Petroni, Robyn Fink, Sarah Hibbitts, James W. Patterson, Naomi Johansen
Publikováno v:
Clinical Cancer Research. 13:6386-6395
Purpose: Human melanoma cells express shared antigens recognized by CD8+ T lymphocytes, the most common of which are melanocytic differentiation proteins and cancer-testis antigens. However, peptide vaccines for melanoma usually target only one or tw
Autor:
Haiyen E. Zhau, Quanjun Cui, Tony T. Wu, Cheryl F. Murphy, Gary Balian, Hua Yang, Chinghai Kao, Robert A. Sikes, George N. Thalmann, Leland W. K. Chung
Publikováno v:
International Journal of Cancer. 77:887-894
LNCaP lineage-derived human prostate cancer cell lines C4-2 and C4-2B4 acquire androgen independence and osseous metastatic potential in vivo. Using C4-2 and C4-2B4 the goals of the current investigation were 1) to establish an ideal bone xenograft m
Autor:
Amber L. Shada, Craig L. Slingluff, Dandan Sun, Anindya Dutta, Aubrey G Wagenseller, Jason A. Papin, Kevin M. D'Auria, Kerrington R. Molhoek, Cheryl F. Murphy
Publikováno v:
Journal of Translational Medicine
Background Targeted therapies directed at commonly overexpressed pathways in melanoma have clinical activity in numerous trials. Little is known about how these therapies influence microRNA (miRNA) expression, particularly with combination regimens.
Autor:
William A. Petri, Beth L. P. Ungar, Jonathan I. Ravdin, Cheryl F. Murphy, Joanna Skilogiannis, Ahmed E. Simjee, Vinodh Gathiram, Terry F. H. G. Jackson
Publikováno v:
Journal of Infectious Diseases. 162:768-772
The recognition of the Entamoeba histolytica galactose-inhibitable adherence lectin by antibodies was studied using sera obtained from subjects in South Africa with an amebic liver abscess or asymptomatically pathogenic or nonpathogenic E. histolytic
Autor:
Galina V. Yamshchikov, Priscilla Merrill, Sarah Hibbitts, William W. Grosh, Cheryl F. Murphy, Robyn Fink, Kimberly A. Chianese-Bullock, Jennifer Pressley, Craig L. Slingluff, Catherine J. Wiernasz, Elizabeth M. H. Woodson, Gina R. Petroni, Eric A. Bissonette, Patrice Y. Neese, Courtney F. Garbee, James W. Patterson
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 174(5)
Twelve peptides derived from melanocyte differentiation proteins and cancer-testis Ags were combined and administered in a single mixture to patients with resected stage IIB, III, or IV melanoma. Five of the 12 peptides included in this mixture had n
Autor:
Yinin Hu, Patrice K. Rehm, Cheryl F. Murphy, Mark E. Smolkin, Andrea Czarkowski, Elizabeth J. Coleman, William W. Grosh, Gina R. Petroni, Walter C. Olson
Publikováno v:
Journal for Immunotherapy of Cancer
Meeting abstracts Melanoma vaccines have been designed to expand specific CD8+ T-cells, but melanoma-reactive helper T-cells also can have antitumor activity. We previously observed clinical activity of a vaccine incorporating 6 melanoma helper pepti
Autor:
Michael J. Weber, Prahlad T. Ram, Cheryl F. Murphy, Jeffrey E. Gershenwald, David L. Brautigan, Alison Gaucher, Amber L. Shada, Lainie P. Martin, Anthony J. Olszanski, Gulsun Erdag, Gina R. Petroni, Sofia M. Shea, Craig L. Slingluff, Kimberly A. Chianese-Bullock, William W. Grosh, Mark E. Smolkin, Kerrington R. Molhoek, Geoffrey R. Weiss, Aubrey G Wagenseller
Publikováno v:
Journal of Clinical Oncology. 30:8530-8530
8530 Background: A CTEP-sponsored phase II trial was performed to evaluate safety and clinical activity of combination therapy with CCI-779 (temsirolimus) and bevacizumab in patients with advanced melanoma. Correlative studies assessed mTOR signaling
Autor:
Cheryl F. Murphy, Jonathan I. Ravdin
Publikováno v:
The Journal of protozoology. 39(2)
We studied galactose (Gal)-specific binding of the soluble purified 260-kDa Entamoeba histolytica adherence protein to glycosylation deficient Chinese hamster ovary (CHO) cell mutants. Our goal was to further define the lectin's functional activity a