Zobrazeno 1 - 10
of 75
pro vyhledávání: '"Cheryl F Lichti"'
Autor:
Hao Hu, Anthony N. Vomund, Orion J. Peterson, Neetu Srivastava, Tiandao Li, Lisa Kain, Wandy L. Beatty, Bo Zhang, Chyi-Song Hsieh, Luc Teyton, Cheryl F. Lichti, Emil R. Unanue, Xiaoxiao Wan
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-22 (2024)
Abstract Autoimmune attack toward pancreatic β cells causes permanent loss of glucose homeostasis in type 1 diabetes (T1D). Insulin secretory granules store and secrete insulin but are also thought to be tissue messengers for T1D. Here, we show that
Externí odkaz:
https://doaj.org/article/38e4150b7348442bba37d66dcf1cb948
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e68516 (2013)
Insulin increases cellular glucose uptake and metabolism in the postprandial state by acutely stimulating the translocation of the Glut4 glucose transporter from intracellular membrane compartments to the cell surface in muscle and fat cells. The int
Externí odkaz:
https://doaj.org/article/23d496e063b049aa999fe9629b79a789
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e73689 (2013)
Our prior research has shown that environmental enrichment (i.e. rats reared in an environment with novel objects, social contact with conspecifics) produces a protective antidepressant-like phenotype in rats and decreases neurobiological effects of
Externí odkaz:
https://doaj.org/article/c79b15b291eb46eb867bfeac9c8b9fef
Publikováno v:
PLoS Pathogens, Vol 6, Iss 5, p e1000919 (2010)
The Haemophilus influenzae HMW1 adhesin is a high-molecular weight protein that is secreted by the bacterial two-partner secretion pathway and mediates adherence to respiratory epithelium, an essential early step in the pathogenesis of H. influenzae
Externí odkaz:
https://doaj.org/article/c047cc87adc84d70a06d09af8f584e5f
Autor:
Padma P. Nanaware, Zohaib N. Khan, Cristina C. Clement, Madhur Shetty, Ines Mota, Ethan S. Seltzer, Monika Dzieciatkowska, Fabia Gamboni, Angelo D’Alessandro, Charles Ng, Manabu Nagayama, Cheryl F. Lichti, Rajesh K. Soni, Jacob B. Geri, Irina Matei, David Lyden, Randy Longman, Theresa T. Lu, Xiaoxiao Wan, Emil R. Unanue, Lawrence J. Stern, Laura Santambrogio
Publikováno v:
Cell Reports, Vol 43, Iss 6, Pp 114311- (2024)
Summary: The lymphatic fluid is the conduit by which part of the tissue “omics” is transported to the draining lymph node for immunosurveillance. Following cannulation of the pre-nodal cervical and mesenteric afferent lymphatics, herein we invest
Externí odkaz:
https://doaj.org/article/957cfb99c70846f691804304c5c2963b
Autor:
Cheryl F. Lichti, Xiaoxiao Wan
Publikováno v:
Semin Immunol
In autoimmune diseases, recognition of self-antigens presented by major histocompatibility complex (MHC) molecules elicits unexpected attack of tissue by autoantibodies and/or autoreactive T cells. Post-translational modification (PTM) may alter the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d8ad23501cdc7ab53e2220679a872a9
https://europepmc.org/articles/PMC10324092/
https://europepmc.org/articles/PMC10324092/
Autor:
Cheryl F. Lichti, Nathalie Vigneron, Karl R. Clauser, Benoit J. Van den Eynde, Michal Bassani-Sternberg
Publikováno v:
Cancer immunology research, (2022)
Within the tumor immunology community, the topic of proteasomal spliced peptides (PSP) has generated a great deal of controversy. In the earliest reports, careful biological validation led to the conclusion that proteasome-catalyzed peptide splicing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9066c16e787e09c982b969fd0538a4a
https://hdl.handle.net/2078.1/259032
https://hdl.handle.net/2078.1/259032
Autor:
Maxim N. Artyomov, Daniele Runci, Ilya Kizhvatov, Ruan F.V. Medrano, Kai W. Wucherpfennig, Danielle M. Lussier, Wei Meng, Cheryl F. Lichti, Kathleen C. F. Sheehan, Jeffrey P. Ward, Tyler Jacks, Alexander Chen, Adrienne M. Luoma, J. Michael White, Elise Alspach, Alexander P. Miceli, Matthew M. Gubin, Emil R. Unanue, Robert D. Schreiber, Michel DuPage, Ekaterina Esaulova, Anthony N. Vomund, Cora D. Arthur
Publikováno v:
PMC
Nature
Nature
The ability of the immune system to eliminate and shape the immunogenicity of tumours defines the process of cancer immunoediting1. Immunotherapies such as those that target immune checkpoint molecules can be used to augment immune-mediated eliminati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d98cb1bdaed9042b4a16e69dd9e0c149
https://doi.org/10.1038/s41586-019-1671-8
https://doi.org/10.1038/s41586-019-1671-8
Autor:
Ana Maria Arbelaez, Emil R. Unanue, Cheryl F. Lichti, Xiaoxiao Wan, Orion J. Peterson, Anthony N. Vomund
Publikováno v:
The Journal of Experimental Medicine
Assessing the self-antigens causing type 1 diabetes remains challenging. This study shows that blood leukocytes contain immunogenic peptides with compatible sequences to those presented in the pancreatic islets, representing a feasible strategy for p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c09190b3f71193d50c0e916853076c3
http://europepmc.org/articles/PMC8034384
http://europepmc.org/articles/PMC8034384
Autor:
Sabin A. Nettles, Katherine Warre-Cornish, Marc J. Tetel, Larry Denner, Lucia Dutan Polit, Deepak Srivastava, Cheryl F. Lichti, Kalpana D. Acharya
Publikováno v:
J Neuroendocrinol
Neural progestin receptors (PR) function in reproduction, neural development, neuroprotection, learning, memory and the anxiety response. In the absence of progestins, PR can be activated by dopamine (DA) in the rodent hypothalamus to elicit female s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9ed0d2c023a2a4d7ff491db0fa33f41
https://doi.org/10.1111/jne.12904
https://doi.org/10.1111/jne.12904