Zobrazeno 1 - 10
of 101
pro vyhledávání: '"Cheryl F Dreyfus"'
Autor:
Yanying Huo, Akshada Sawant, Yongmei Tan, Amar H Mahdi, Tao Li, Hui Ma, Vrushank Bhatt, Run Yan, Jake Coleman, Cheryl F Dreyfus, Jessie Yanxiang Guo, M Maral Mouradian, Eileen White, Bing Xia
Publikováno v:
PLoS Genetics, Vol 18, Iss 4, p e1010138 (2022)
The PALB2 tumor suppressor plays key roles in DNA repair and has been implicated in redox homeostasis. Autophagy maintains mitochondrial quality, mitigates oxidative stress and suppresses neurodegeneration. Here we show that Palb2 deletion in the mou
Externí odkaz:
https://doaj.org/article/a14fbad6b37441618cc40a94f6c51743
Autor:
Issa P Bagayogo, Cheryl F Dreyfus
Publikováno v:
ASN Neuro, Vol 1 (2009)
A number of studies suggest that OLGs (oligodendrocytes), the myelinating cells of the central nervous system, are also a source of trophic molecules, such as neurotrophins that may influence survival of proximate neurons. What is less clear is how t
Externí odkaz:
https://doaj.org/article/312021fa9fc44ab2b1598ca95541747c
Autor:
Ashish Patel, Kyle S. Saitta, Cheryl F. Dreyfus, Lauren D. Lercher, Yangyang Huang, Geoffrey McAuliffe, Danielle M. Sainato
Publikováno v:
Glia
It is well recognized that astrocytes can produce factors known to affect the myelination process. One such factor, brain-derived neurotrophic factor (BDNF), can enhance the differentiation of oligodendrocyte lineage cells following a demyelinating l
Autor:
Yanying Huo, Akshada Sawant, Yongmei Tan, Amar H Mahdi, Tao Li, Hui Ma, Vrushank Bhatt, Run Yan, Jake Coleman, Cheryl F Dreyfus, Jessie Yanxiang Guo, M. Maral Mouradian, Eileen White, Bing Xia
Publikováno v:
PLoS genetics. 18(4)
The PALB2 tumor suppressor plays key roles in DNA repair and has been implicated in redox homeostasis. Autophagy maintains mitochondrial quality, mitigates oxidative stress and suppresses neurodegeneration. Here we show that Palb2 deletion in the mou
Autor:
M. Maral Mouradian, Jake Coleman, Run Yan, Bing Xia, Tao Li, Vrushank Bhatt, Eileen White, Hui Ma, Cheryl F. Dreyfus, Yanying Huo, Jessie Yanxiang Guo, Amar H. Mahdi, Akshada Sawant, Yongmei Tan
SummaryThe PALB2 tumor suppressor plays key roles in DNA repair and has been implicated in redox homeostasis. Autophagy maintains mitochondrial quality, mitigates oxidative stress and suppresses neurodegeneration. Here we show that Palb2 deletion in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::500822e0665046114f1cdef9f1c1cf4e
https://doi.org/10.1101/2021.06.07.447248
https://doi.org/10.1101/2021.06.07.447248
Publikováno v:
Neurobiology of Disease, Vol 7, Iss 6, Pp 574-585 (2000)
Recent studies suggest that the injured adult spinal cord responds to brain-derived neurotrophic factor (BDNF) and neurotrophin-3 (NT3) with enhanced neuron survival and axon regeneration. Potential neurotrophin sources and cellular localization in s
Externí odkaz:
https://doaj.org/article/b18aaaddb8a041f88fe3606d37ea6e8a
Publikováno v:
Brain Res
Astrocytes are traditionally recognized for their multiple roles in support of brain function. However, additional changes in these roles are evident in response to brain diseases. In this review, we highlight positive and negative effects of astrocy
Publikováno v:
The Journal of Biological Chemistry
Macroautophagy dysregulation is implicated in multiple neurological disorders, such as Parkinson's disease. While autophagy pathways are heavily researched in heterologous cells and neurons, regulation of autophagy in the astrocyte, the most abundant
Autor:
Anna Dunaevsky, Ragunathan Padmashri, Peng Jiang, Cheryl F. Dreyfus, Hyosung Kim, Ying Liu, Ranjie Xu
Publikováno v:
Stem Cell Reports, Vol 12, Iss 5, Pp 890-905 (2019)
Summary: The process of oligodendrogenesis has been relatively well delineated in the rodent brain. However, it remains unknown whether analogous developmental processes are manifested in the human brain. Here we report oligodendrogenesis in forebrai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b6ff5a2dfa28af5acae591f9bdd5d9b
https://europepmc.org/articles/PMC6524754/
https://europepmc.org/articles/PMC6524754/
Publikováno v:
Developmental Neurobiology. 76:780-798
Valproic acid (VPA) is a neurotherapeutic drug prescribed for seizures, bipolar disorder, and migraine, including women of reproductive age. VPA is a well-known teratogen that produces congenital malformations in many organs including the nervous sys