Zobrazeno 1 - 10
of 72
pro vyhledávání: '"Cheryl F, Lichti"'
Autor:
Hao Hu, Anthony N. Vomund, Orion J. Peterson, Neetu Srivastava, Tiandao Li, Lisa Kain, Wandy L. Beatty, Bo Zhang, Chyi-Song Hsieh, Luc Teyton, Cheryl F. Lichti, Emil R. Unanue, Xiaoxiao Wan
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-22 (2024)
Abstract Autoimmune attack toward pancreatic β cells causes permanent loss of glucose homeostasis in type 1 diabetes (T1D). Insulin secretory granules store and secrete insulin but are also thought to be tissue messengers for T1D. Here, we show that
Externí odkaz:
https://doaj.org/article/38e4150b7348442bba37d66dcf1cb948
Autor:
Padma P. Nanaware, Zohaib N. Khan, Cristina C. Clement, Madhur Shetty, Ines Mota, Ethan S. Seltzer, Monika Dzieciatkowska, Fabia Gamboni, Angelo D’Alessandro, Charles Ng, Manabu Nagayama, Cheryl F. Lichti, Rajesh K. Soni, Jacob B. Geri, Irina Matei, David Lyden, Randy Longman, Theresa T. Lu, Xiaoxiao Wan, Emil R. Unanue, Lawrence J. Stern, Laura Santambrogio
Publikováno v:
Cell Reports, Vol 43, Iss 6, Pp 114311- (2024)
Summary: The lymphatic fluid is the conduit by which part of the tissue “omics” is transported to the draining lymph node for immunosurveillance. Following cannulation of the pre-nodal cervical and mesenteric afferent lymphatics, herein we invest
Externí odkaz:
https://doaj.org/article/957cfb99c70846f691804304c5c2963b
Autor:
Federico Scala, Miroslav N. Nenov, Elizabeth J. Crofton, Aditya K. Singh, Oluwarotimi Folorunso, Yafang Zhang, Brent C. Chesson, Norelle C. Wildburger, Thomas F. James, Musaad A. Alshammari, Tahani K. Alshammari, Hannah Elfrink, Claudio Grassi, James M. Kasper, Ashley E. Smith, Jonathan D. Hommel, Cheryl F. Lichti, Jai S. Rudra, Marcello D’Ascenzo, Thomas A. Green, Fernanda Laezza
Publikováno v:
Cell Reports, Vol 23, Iss 2, Pp 555-567 (2018)
Summary: Resilience and vulnerability to neuropsychiatric disorders are linked to molecular changes underlying excitability that are still poorly understood. Here, we identify glycogen-synthase kinase 3β (GSK3β) and voltage-gated Na+ channel Nav1.6
Externí odkaz:
https://doaj.org/article/dc94cfdd1eef4764a9b23adba0a07db4
Autor:
Cheryl F. Lichti, Xiaoxiao Wan
Publikováno v:
Semin Immunol
In autoimmune diseases, recognition of self-antigens presented by major histocompatibility complex (MHC) molecules elicits unexpected attack of tissue by autoantibodies and/or autoreactive T cells. Post-translational modification (PTM) may alter the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d8ad23501cdc7ab53e2220679a872a9
https://europepmc.org/articles/PMC10324092/
https://europepmc.org/articles/PMC10324092/
Autor:
Norelle C. Wildburger, Cheryl F. Lichti, Richard D. LeDuc, Mary Schmidt, Roger A. Kroes, Joseph R. Moskal, Carol L. Nilsson
Publikováno v:
EuPA Open Proteomics, Vol 8, Iss C, Pp 94-103 (2015)
Bone marrow-derived human mesenchymal stem cells (BM-hMSCs) show promise as cell-based delivery vehicles for anti-glioma therapeutics, due to innate tropism for gliomas. However, in clinically relevant human-in-mouse glioma stem cell xenograft models
Externí odkaz:
https://doaj.org/article/1246121ec9ef4c82972fd2a1cebfd6f9
Autor:
Cheryl F. Lichti, Norelle C. Wildburger, Alexander S. Shavkunov, Ekaterina Mostovenko, Huiling Liu, Erik P. Sulman, Carol L. Nilsson
Publikováno v:
EuPA Open Proteomics, Vol 8, Iss C, Pp 85-93 (2015)
Glioma stem-like cells (GSCs) are hypothesized to provide a repository of cells in tumors that can self-replicate and are radio- and chemo-resistant. GSC lines, representing several glioma subtypes, have been isolated and characterized at the transcr
Externí odkaz:
https://doaj.org/article/e4ebd1550ff149ed96ff743523da31fa
Autor:
Cheryl F. Lichti, Nathalie Vigneron, Karl R. Clauser, Benoit J. Van den Eynde, Michal Bassani-Sternberg
Publikováno v:
Cancer immunology research, (2022)
Within the tumor immunology community, the topic of proteasomal spliced peptides (PSP) has generated a great deal of controversy. In the earliest reports, careful biological validation led to the conclusion that proteasome-catalyzed peptide splicing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9066c16e787e09c982b969fd0538a4a
https://hdl.handle.net/2078.1/259032
https://hdl.handle.net/2078.1/259032
Autor:
Maxim N. Artyomov, Daniele Runci, Ilya Kizhvatov, Ruan F.V. Medrano, Kai W. Wucherpfennig, Danielle M. Lussier, Wei Meng, Cheryl F. Lichti, Kathleen C. F. Sheehan, Jeffrey P. Ward, Tyler Jacks, Alexander Chen, Adrienne M. Luoma, J. Michael White, Elise Alspach, Alexander P. Miceli, Matthew M. Gubin, Emil R. Unanue, Robert D. Schreiber, Michel DuPage, Ekaterina Esaulova, Anthony N. Vomund, Cora D. Arthur
Publikováno v:
PMC
Nature
Nature
The ability of the immune system to eliminate and shape the immunogenicity of tumours defines the process of cancer immunoediting1. Immunotherapies such as those that target immune checkpoint molecules can be used to augment immune-mediated eliminati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d98cb1bdaed9042b4a16e69dd9e0c149
https://doi.org/10.1038/s41586-019-1671-8
https://doi.org/10.1038/s41586-019-1671-8
Autor:
Cheryl F. Lichti, Xiuzhen eFan, Robert D. English, Yafang eZhang, Dingge eLi, Fanping eKong, Mala eSinha, Clark R. Andersen, Heidi eSpratt, Bruce A. Luxon, Thomas A. Green
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 8 (2014)
Prior research demonstrated that environmental enrichment creates individual differences in behavior leading to a protective addiction phenotype in rats. Understanding the mechanisms underlying this phenotype will guide selection of targets for much-
Externí odkaz:
https://doaj.org/article/eb4e8834ac304ea8bf429156fbd73687
Autor:
Ana Maria Arbelaez, Emil R. Unanue, Cheryl F. Lichti, Xiaoxiao Wan, Orion J. Peterson, Anthony N. Vomund
Publikováno v:
The Journal of Experimental Medicine
Assessing the self-antigens causing type 1 diabetes remains challenging. This study shows that blood leukocytes contain immunogenic peptides with compatible sequences to those presented in the pancreatic islets, representing a feasible strategy for p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c09190b3f71193d50c0e916853076c3
http://europepmc.org/articles/PMC8034384
http://europepmc.org/articles/PMC8034384