Výsledky vyhledávání - "Cheryl Eppolito"

Akademický článek

Oncolytic Maraba virus armed with tumor antigen boosts vaccine priming and reveals diverse therapeutic response patterns when combined with checkpoint blockade in ovarian cancer

Autor: A. J. Robert McGray, Ruea-Yea Huang, Sebastiano Battaglia, Cheryl Eppolito, Anthony Miliotto, Kyle B. Stephenson, Amit A. Lugade, Gill Webster, Brian D. Lichty, Mukund Seshadri, Danuta Kozbor, Kunle Odunsi

Publikováno v: Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-16 (2019)

Abstract Background Cancer immunotherapies are emerging as promising treatment strategies for ovarian cancer patients that experience disease relapse following first line therapy. As such, identifying strategies to bolster anti-tumor immunity and lim

Externí odkaz: https://doaj.org/article/80478d4009594eabbb5adee11254fa6a

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Akademický článek

Fidelity of human ovarian cancer patient-derived xenografts in a partially humanized mouse model for preclinical testing of immunotherapies

Autor: Ruea-Yea Huang, Cheryl Eppolito, Adekunle Odunsi, A J Robert McGray, Adebukola Abiola

Publikováno v: Journal for ImmunoTherapy of Cancer, Vol 8, Iss 2 (2020)

Background Immune checkpoint blockers (ICBs) have been approved by the Food and Drug Administration to be used alone in front-line therapies or in combination with other regimens for certain advanced cancers. Since ICB only works in a subset of patie

Externí odkaz: https://doaj.org/article/01b53e8b84204e7e867eec1a252249a1

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Tcf-1 protects anti-tumor TCR-engineered CD8

Autor: Brendan, Zangari, Takemasa, Tsuji, Junko, Matsuzaki, Hemn, Mohammadpour, Cheryl, Eppolito, Sebastiano, Battaglia, Fumito, Ito, Thinle, Chodon, Richard, Koya, A J, Robert McGray, Kunle, Odunsi

Publikováno v: Cancer immunology, immunotherapy : CII. 71(12)

T-cell longevity is undermined by antigen-driven differentiation programs that render cells prone to attrition through several mechanisms. CD8 Tcf-1 mRNA encoding TCF-1B and TCF-1E isoforms, along with GzmB expression were assessed in CD62L TCF-1B an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::af25937fc54cb5aeedcde87f10bea697
https://pubmed.ncbi.nlm.nih.gov/35666273

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CXCR6 by increasing retention of memory CD8+ T cells in the ovarian tumor microenvironment promotes immunosurveillance and control of ovarian cancer

Autor: Cheryl Eppolito, Protul Shrikant, Anthony Miliotto, Richard Koya, Junko Matsuzaki, Sebastiano Battaglia, Wenjun He, Aj Robert McGray, Thinle Chodon, Ravikumar Muthuswamy, Kunle Odunsi, Brian D. Lichty, Tsuji Takemasa

Publikováno v: Journal for ImmunoTherapy of Cancer, Vol 9, Iss 10 (2021)

PurposeResident memory CD8 T cells, owing to their ability to reside and persist in peripheral tissues, impart adaptive sentinel activity and amplify local immune response, and have beneficial implications for tumor surveillance and control. The curr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::007198670e49357d378e5daf631c8ad2
https://jitc.bmj.com/content/9/10/e003329.full

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CXCR6 by increasing retention of memory CD8

Autor: Ravikumar, Muthuswamy, Aj Robert, McGray, Sebastiano, Battaglia, Wenjun, He, Anthony, Miliotto, Cheryl, Eppolito, Junko, Matsuzaki, Tsuji, Takemasa, Richard, Koya, Thinle, Chodon, Brian D, Lichty, Protul, Shrikant, Kunle, Odunsi

Publikováno v: Journal for Immunotherapy of Cancer

Purpose Resident memory CD8 T cells, owing to their ability to reside and persist in peripheral tissues, impart adaptive sentinel activity and amplify local immune response, and have beneficial implications for tumor surveillance and control. The cur

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::74b93ce8d7de1da9170e29e000fc4131
https://pubmed.ncbi.nlm.nih.gov/34607898

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Oncolytic Maraba virus armed with tumor antigen boosts vaccine priming and reveals diverse therapeutic response patterns when combined with checkpoint blockade in ovarian cancer

Autor: Ruea-Yea Huang, Brian D. Lichty, Amit A. Lugade, Cheryl Eppolito, Sebastiano Battaglia, Kunle Odunsi, Anthony Miliotto, Gill A. Webster, Kyle B Stephenson, AJ Robert McGray, Mukund Seshadri, Danuta Kozbor

Publikováno v: Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-16 (2019)
Journal for Immunotherapy of Cancer

Background Cancer immunotherapies are emerging as promising treatment strategies for ovarian cancer patients that experience disease relapse following first line therapy. As such, identifying strategies to bolster anti-tumor immunity and limit immune

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9739c284b3c05ddb8c43620119b27281
http://link.springer.com/article/10.1186/s40425-019-0641-x

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CXCR6 by increasing retention of memory CD8 T cells in the ovarian tumor microenvironment promotes immunosurveillance and control of ovarian cancer

Autor: Sebastiano Battaglia, Ravikumar Muthuswamy, Anthony Miliotto, Wenjun He, AJ Robert McGray, Cheryl Eppolito, Protul Shrikant, Brian D. Lichty, Kunle Odunsi

PurposeResident memory CD8 T cells owing to their ability to reside and persist in peripheral tissues, impart adaptive sentinel activity and amplify local immune response, have beneficial implications for tumor surveillance and control. The current s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::21e83f0d7cdca2322770a1caede736db
https://doi.org/10.1101/2020.12.02.401729

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