Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Cheryl D. Overton"'
Autor:
Steven L. Gonias, Alban Gaultier, Benjamin F. Cravatt, Sherry Niessen, Sanja Arandjelovic, Sergio Fazio, MacRae F. Linton, Cheryl D. Overton, W. Marie Campana
Publikováno v:
Blood. 111:5316-5325
Low-density lipoprotein receptor–related protein (LRP-1) functions in endocytosis and in cell signaling directly (by binding signaling adaptor proteins) or indirectly (by regulating levels of other cell-surface receptors). Because recent studies in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19275bce60f8d86b3460cab7bb4eb793
https://doi.org/10.1182/blood-2007-12-127613
https://doi.org/10.1182/blood-2007-12-127613
Autor:
Daping Fan, Sergio Fazio, Lei Ding, John L. Blakemore, Youmin Zhang, Patricia G. Yancey, Cheryl D. Overton, MacRae F. Linton
Objective—The balance between apoptosis susceptibility and efferocytosis of macrophages is central to plaque remodeling and inflammation. LRP-1 and its ligand, apolipoprotein E, have been implicated in efferocytosis and apoptosis in some cell types
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0095036a675ccc62a53603ba3080aa7
https://europepmc.org/articles/PMC2845445/
https://europepmc.org/articles/PMC2845445/
Autor:
Sergio Fazio, Cheryl D. Overton, MacRae F. Linton, Shenfeng Qiu, Larry L. Swift, Daping Fan, W. Gray Jerome, Patricia G. Yancey
Publikováno v:
The Journal of biological chemistry. 282(18)
Human apoE is a multifunctional and polymorphic protein synthesized and secreted by liver, brain, and tissue macrophages. Here we show that apoE isoforms and mutants expressed through lentiviral transduction display cell-specific differences in secre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10af0b7f8714e88270d5860d77acb3ea
https://pubmed.ncbi.nlm.nih.gov/17341585
https://pubmed.ncbi.nlm.nih.gov/17341585
Publikováno v:
Circulation research. 100(5)
Macrophage low-density lipoprotein receptor–related protein (LRP) mediates internalization of remnant lipoproteins, and it is generally thought that blocking lipoprotein internalization will reduce foam cell formation and atherogenesis. Therefore,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62b55683166639be904ad25772d8617d
https://pubmed.ncbi.nlm.nih.gov/17303763
https://pubmed.ncbi.nlm.nih.gov/17303763