Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Cheryl C. Y. Li"'
Publikováno v:
Frontiers in Oncology, Vol 2 (2012)
Mutations in isocitrate dehydrogenase (IDH) -1 or -2 are found in the majority of WHO grade II and III astrocytomas and oligodendrogliomas, and secondary glioblastomas. Almost all described mutations are heterozygous missense mutations affecting a co
Externí odkaz:
https://doaj.org/article/309e287f27ae45d3a4c15ae8b7db9b66
Autor:
Cheryl C Y Li, Jennifer E Cropley, Mark J Cowley, Thomas Preiss, David I K Martin, Catherine M Suter
Publikováno v:
PLoS Genetics, Vol 7, Iss 4, p e1001380 (2011)
Epigenetic changes can be induced by adverse environmental exposures, such as nutritional imbalance, but little is known about the nature or extent of these changes. Here we have explored the epigenomic effects of a sustained nutritional change, exce
Externí odkaz:
https://doaj.org/article/21344088d00b45d6ab637efa00110c01
Autor:
Mark A. Febbraio, Thomas Preiss, Michael E. Buckland, Jennifer E. Cropley, Cheryl C. Y. Li, Paul E. Young, Christopher A. Maloney, Gregory J. Cooney, Sally A. Eaton, David I. K. Martin, Mark J. Cowley, Darren C. Henstridge, Catherine M. Suter
Publikováno v:
Epigenetics
Intrauterine nutrition can program metabolism, creating stable changes in physiology that may have significant health consequences. The mechanism underlying these changes is widely assumed to involve epigenetic changes to the expression of metabolic
Autor:
Simon Flanagan, Ruta Gupta, Maggie Lee, Michael E. Buckland, Brindha Shivalingham, Cheryl C. Y. Li, Helen Wheeler, Sanaz Maleki
Publikováno v:
Modern Pathology. 26:619-625
Mutations in isocitrate dehydrogenase -1 or -2 (IDH1 or IDH2) are found in the majority of WHO grade II and III diffuse gliomas and secondary glioblastomas. IDH mutation screening is rapidly becoming part of the routine pathological work up of human
Autor:
Alastair Aiken, Catherine M. Suter, Suzy S. J. Hur, Edwina Wing-Lun, Cheryl C. Y. Li, Sally A. Eaton, Paul E. Young, Jennifer E. Cropley, Michael E. Buckland
The complex interaction between obesity, Western-style diets, and cardiovascular disease is of increasing interest, with a growing number of children being born to obese parents with poor lifestyle choices. These offspring have themselves an increase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a182ed5fe2231e4b6aed1ca79d28d6d
https://europepmc.org/articles/PMC4939929/
https://europepmc.org/articles/PMC4939929/
Autor:
Catherine M. Suter, Brindha Shivalingam, Cheryl C. Y. Li, Maggie Lee, Michael E. Buckland, Trina Lum, Paul Wilcox, Kimberley L. Kaufman, Jeffrey Brennan
Publikováno v:
Acta Neuropathologica. 129:147-149
biology, clinical trial design, and future treatment deci-sions. OA should not be ignored in the proposed new clas-sification guidelines [2].Sahm and colleagues studied 43 cases diagnosed as OA based on histology. But in 30 of these cases, immunosta
Publikováno v:
Epigenomics. 2:539-549
Within the Western world’s aging and increasingly overweight population, we are seeing an increasing prevalence of adult-onset, lifestyle-related disease such as diabetes, hypertension and atherosclerosis. There is significant evidence that subopti
Autor:
Rupert Shuttleworth, Cheryl C. Y. Li, Valery Combes, Paul E. Young, Maggie Lee, Georges E. Grau, Joyce Gong, Sally A. Eaton, Susan Brammah, Mary Bebawy, Catherine M. Suter, David T. Humphreys, Michael E. Buckland
Publikováno v:
RNA Biology
Interactions between glioma cells and their local environment are critical determinants of brain tumor growth, infiltration and neovascularisation. Communication with host cells and stroma via microvesicles represents one pathway by which tumors can
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fe17a24accaef0cb2297eb3699ad8c2
https://hdl.handle.net/10453/2365810453/36917
https://hdl.handle.net/10453/2365810453/36917
Publikováno v:
Frontiers in Oncology
Frontiers in Oncology, Vol 2 (2012)
Frontiers in Oncology, Vol 2 (2012)
Mutations in isocitrate dehydrogenase (IDH) -1 or -2 are found in the majority of WHO grade II and III astrocytomas and oligodendrogliomas, and secondary glioblastomas. Almost all described mutations are heterozygous missense mutations affecting a co
Autor:
Maggie Lee, Catherine M. Suter, Simon Flanagan, Cheryl C. Y. Li, Ruta Gupta, Michael E. Buckland
Publikováno v:
Pathology. 44:S70
O 6 -methylguanine-DNA methyltransferase (MGMT) is a DNA repair enzyme which is commonly hypermethylated in glioblas-tomas. Methylation of the MGMT promoter is associated with an improved response to alkylating agent chemotherapy and patient survival