Zobrazeno 1 - 10
of 311
pro vyhledávání: '"Cheryl A Frye"'
Publikováno v:
Frontiers in Systems Neuroscience, Vol 8 (2014)
A novel factor of interest for growth/plasticity in the brain is pregnane xenobiotic receptor (PXR). PXR is a liver factor known for its role in xenobiotic clearance and cholesterol metabolism. It is expressed in the brain, suggesting a potential rol
Externí odkaz:
https://doaj.org/article/cdd6ba9b47c7486ab1368137c52f426a
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 8 (2014)
Neurosteroids are cholesterol-based hormones that can be produced in the brain, independent of secretion from peripheral endocrine glands, such as the gonads and adrenals. A focus in our laboratory for over 25 years has been how production of the pre
Externí odkaz:
https://doaj.org/article/01fbf014858f4742b124b1532b570d7c
Autor:
Alicia A Walf, Cheryl A Frye
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 6 (2012)
Stressors, during early life or adulthood, can alter steroid-sensitive behaviors, such as exploration, anxiety, and/or cognitive processes. We investigated if exposure to acute stressors in adulthood may alter behavioral and neuroendocrine responses
Externí odkaz:
https://doaj.org/article/2d2f7903e2e440a1a0c120add9ade952
Publikováno v:
Frontiers in Neuroscience, Vol 5 (2012)
Progestogens [progesterone (P4) and its products] play fundamental roles in the development and/or function of the central nervous system during pregnancy. We, and others, have investigated the role of pregnane neurosteroids for a plethora of functio
Externí odkaz:
https://doaj.org/article/aac5982e919d466fb1fc8eacf4179a27
Publikováno v:
Frontiers in Psychiatry, Vol 2 (2011)
Maternal-offspring interactions begin prior to birth. Experiences of the mother during gestation play a powerful role in determining the developmental programming of the central nervous system. In particular, stress during gestation alters developmen
Externí odkaz:
https://doaj.org/article/b4daa3146af5405c9404f636123199bc
Publikováno v:
Frontiers in Aging Neuroscience, Vol 2 (2010)
Some hippocampally-influenced affective and/or cognitive processes decline with aging. The role of androgens in this process is of interest. Testosterone (T) is aromatized to estrogen, and reduced to dihydrotestosterone (DHT), which is converted to 5
Externí odkaz:
https://doaj.org/article/1330955e704a49fda4953b3d74f45ff7
Autor:
Amy S, Kohtz, Cheryl A, Frye
Publikováno v:
Current Neuropharmacology. 21:1606-1616
Background: Masculine sexual behaviors are dependent on androstane-derived steroids; however, the modulatory effects of mating, and of mating control, on androstane neurosteroidogenesis remain largely unknown. Objective: Herein, we investigated the e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::365ccfff9d2fea2f92c3dea50b423985
https://doi.org/10.2174/1570159x21666221019114535
https://doi.org/10.2174/1570159x21666221019114535
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 14 (2020)
The neurosteroid, 5α-pregnan-3α-ol-20-one (known as “allopregnanolone” or 3α,5α-THP), is produced in the midbrain ventral tegmental area (VTA), independent of peripheral sources of progestogens, where it has potential actions at N-methyl-D-as
Externí odkaz:
https://doaj.org/article/0b646619a1be42bda9105b4110ea113a
Autor:
Cheryl A. Frye, Vincent F. Lembo
Publikováno v:
Antioxidants-Benefits, Sources, Mechanisms of Action
One Health is a principle that takes into account the interactions of humans, animals, the surrounding environment, and how they affect each other. In order to examine this concept in an experimental paradigm, the effects and benefits of wild Alaskan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::682ba463caf103ea8d1e49bacd3cfe61
https://mts.intechopen.com/articles/show/title/one-health-and-the-positive-effects-of-alaskan-blueberries
https://mts.intechopen.com/articles/show/title/one-health-and-the-positive-effects-of-alaskan-blueberries
Publikováno v:
Reproductive Hormones
The clinical literature and recent studies in our laboratory using rodent models demonstrate that there are individual differences in androgens’ pleiotropic effects across the lifespan that need to be better understood. The question to address that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22c4808070f48bd5c1e4cd9e378468e2
http://www.intechopen.com/articles/show/title/androgens-effects-across-the-lifespan-in-men-and-animal-models
http://www.intechopen.com/articles/show/title/androgens-effects-across-the-lifespan-in-men-and-animal-models