Zobrazeno 1 - 10
of 215
pro vyhledávání: '"Cheryl A, London"'
Autor:
Gretchen P. McLinden, Anne C. Avery, Heather L. Gardner, Kelly Hughes, Angie M. Rodday, Kexuan Liang, Cheryl A. London
Publikováno v:
Journal of Veterinary Internal Medicine, Vol 38, Iss 3, Pp 1666-1674 (2024)
Abstract Background To explore the safety and utility of combining low dose single‐agent doxorubicin with a canine specific anti‐CD20 monoclonal antibody (1E4‐cIgGB) in client owned dogs with untreated B‐cell lymphoma. Animals Forty‐two cli
Externí odkaz:
https://doaj.org/article/298dea408eb844359dba10c2e4026ea5
Autor:
Jadesola Temitope Olayinka, Akanksha Nagarkar, Diana Junyue Ma, Neil B. Wong, Andrew Romasco, Cesar Piedra-Mora, Linda Wrijil, Clement N. David, Heather L. Gardner, Nicholas A. Robinson, Kelly L. Hughes, Bruce Barton, Cheryl A. London, Ramón M. Almela, Jillian M. Richmond
Publikováno v:
Frontiers in Veterinary Science, Vol 10 (2023)
Cutaneous T-cell lymphoma (CTCL) is an uncommon type of lymphoma involving malignant skin-resident or skin-homing T cells. Canine epitheliotropic lymphoma (EL) is the most common form of CTCL in dogs, and it also spontaneously arises from T lymphocyt
Externí odkaz:
https://doaj.org/article/073a508055a14180ac8f458d7bea2ad7
Autor:
Katherine Dittrich, Ümmügülsüm Yıldız-Altay, Fatima Qutab, Danny A Kwong, Zechuan Rao, Sebastian A Nievez-Lozano, Heather L Gardner, Jillian M Richmond, Cheryl A London
Publikováno v:
PLoS ONE, Vol 18, Iss 8, p e0290428 (2023)
Pet dogs develop spontaneous diffuse large B cell lymphoma (DLBCL), and veterinary clinical trials have been employed to treat canine DLBCL and to inform clinical trials for their human companions. A challenge that remains is selection of treatment t
Externí odkaz:
https://doaj.org/article/c3e092a2d8ea4b18bd9e6af5fc3eab48
Autor:
Asma Boukhalfa, Sally R Robinson, Dawn M Meola, Nicholas A Robinson, Lauren A Ling, Joey N LaMastro, Jenica N Upshaw, Lakshmi Pulakat, Iris Z Jaffe, Cheryl A London, Howard H Chen, Vicky K Yang
Publikováno v:
PLoS ONE, Vol 18, Iss 3, p e0282859 (2023)
Chemotherapy-induced impairment of autophagy is implicated in cardiac toxicity induced by anti-cancer drugs. Imperfect translation from rodent models and lack of in vitro models of toxicity has limited investigation of autophagic flux dysregulation,
Externí odkaz:
https://doaj.org/article/5ea7be9f4e1b4e42ab80d1fbc2e93b4d
Autor:
Kate Megquier, Jason Turner-Maier, Kathleen Morrill, Xue Li, Jeremy Johnson, Elinor K Karlsson, Cheryl A London, Heather L Gardner
Publikováno v:
PLoS ONE, Vol 17, Iss 9, p e0274383 (2022)
The characterization of immortalized canine osteosarcoma (OS) cell lines used for research has historically been based on phenotypic features such as cellular morphology and expression of bone specific markers. With the increasing use of these cell l
Externí odkaz:
https://doaj.org/article/141e55c5532a44ba85cdda09c7b40708
Publikováno v:
BMC Veterinary Research, Vol 15, Iss 1, Pp 1-7 (2019)
Abstract Background Oclacitinib is an orally bioavailable Janus Kinase (JAK) inhibitor approved for the treatment of canine atopic dermatitis. Aberrant JAK/ Signal Transducer and Activator of Transcription (STAT) signaling within hematologic and soli
Externí odkaz:
https://doaj.org/article/b3540c6a70c34a788966a76f1d284b6d
Autor:
Terry J. Shackleford, Seethalakshmi Hariharan, Angelina V. Vaseva, Karina Alagoa, Maricruz Espinoza, Hemant K. Bid, Fuyang Li, Haihong Zhong, Doris A. Phelps, Ryan D. Roberts, Hakan Cam, Cheryl A. London, Denis C. Guttridge, Yidong Chen, Manjeet Rao, Yuzuru Shiio, Peter J. Houghton
Publikováno v:
Molecular Cancer Therapeutics. 22:539-550
Antibodies targeting insulin-like growth factor 1 receptor (IGF-1R) induce objective responses in only 5% to 15% of children with sarcoma. Understanding the mechanisms of resistance may identify combination therapies that optimize efficacy of IGF-1R
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cc1a9c642cb58054bfc64c2b503e27f7
https://doi.org/10.1158/1535-7163.mct-20-0625
https://doi.org/10.1158/1535-7163.mct-20-0625
Autor:
Abbey R. Sadowski, Heather L. Gardner, Antonella Borgatti, Heather Wilson, David M. Vail, Joshua Lachowicz, Christina Manley, Avenelle Turner, Mary K. Klein, Angharad Waite, Alexandra Sahora, Cheryl A. London
Publikováno v:
BMC Veterinary Research, Vol 14, Iss 1, Pp 1-7 (2018)
Abstract Background Chemotherapeutic options for the treatment of canine lymphoma have not changed in several decades necessitating the identification of new therapeutics to improve patient outcome. KPT-335 (verdinexor) is a novel orally bioavailable
Externí odkaz:
https://doaj.org/article/5970ac9c08524ac99e1ae4efc81b1bbf
Publikováno v:
BMC Veterinary Research, Vol 13, Iss 1, Pp 1-9 (2017)
Abstract Background Hyperthermia is an established anti-cancer treatment but is limited by tolerance of adjacent normal tissues. Parenteral administration of gold nanorods (NRs) as a photosensitizer amplifies the effects of hyperthermia treatment whi
Externí odkaz:
https://doaj.org/article/b27046c549ba4175a137265793bd37a0
Autor:
Peter J. Houghton, Yuzuru Shiio, Manjeet Rao, Yidong Chen, Denis C. Guttridge, Cheryl A. London, Hakan Cam, Ryan D. Roberts, Doris A. Phelps, Haihong Zhong, Fuyang Li, Hemant K. Bid, Maricruz Espinoza, Karina Alagoa, Angelina V. Vaseva, Seethalakshmi Hariharan, Terry J. Shackleford
Supplemental data
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d321c73b0c1dff621814f82b8502466
https://doi.org/10.1158/1535-7163.22551828
https://doi.org/10.1158/1535-7163.22551828
