Zobrazeno 1 - 10
of 311
pro vyhledávání: '"Cheryl A, Frye"'
Autor:
Amy S, Kohtz, Cheryl A, Frye
Publikováno v:
Current Neuropharmacology. 21:1606-1616
Background: Masculine sexual behaviors are dependent on androstane-derived steroids; however, the modulatory effects of mating, and of mating control, on androstane neurosteroidogenesis remain largely unknown. Objective: Herein, we investigated the e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::365ccfff9d2fea2f92c3dea50b423985
https://doi.org/10.2174/1570159x21666221019114535
https://doi.org/10.2174/1570159x21666221019114535
Publikováno v:
Frontiers in Endocrinology, Vol 11 (2021)
Progestogens' (e.g., progesterone and its neuroactive metabolite, allopregnanolone), cognitive effects and mechanisms among males are not well-understood. We hypothesized if progestogen's effects on cognitive performance are through its metabolite al
Externí odkaz:
https://doaj.org/article/0c349454832c444ba2ed12fb6829e323
Publikováno v:
Neurobiology of Stress, Vol 12, Iss , Pp - (2020)
Prenatal stress (PNS) can influence behaviors associated with cognition, reward and emotional regulation, which are controlled by brain areas such as the cortex, hippocampus, hypothalamus, midbrain and cerebellum. Allopregnanolone in these regions mo
Externí odkaz:
https://doaj.org/article/ff05497a03ce4909b48a35bcb61b53af
Autor:
Cheryl A. Frye, Sridar V. Chittur
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 14 (2020)
Among female rats, mating enhances neurosteroid formation in the midbrain ventral tegmental area (VTA; independent of peripheral steroid-secreting glands, ovaries, and adrenals). The sources/targets for these actions are not well understood. In Exper
Externí odkaz:
https://doaj.org/article/038ca32ca0b94595843dfdb5d2478d47
Autor:
Amy Stave Kohtz, Cheryl A. Frye
Publikováno v:
Frontiers in Neuroscience, Vol 14 (2020)
Engagement in sexual behavior can impact neurosteroidogenesis, in particular production of the prohormone testosterone (T) and likely its subsequent metabolism to 5α-androstane-3α-17β-Diol (3α-Diol) or aromatization to estradiol (E2). Androgens a
Externí odkaz:
https://doaj.org/article/5acb68626b0940f49bcecaeb46277a31
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 14 (2020)
The neurosteroid, 5α-pregnan-3α-ol-20-one (known as “allopregnanolone” or 3α,5α-THP), is produced in the midbrain ventral tegmental area (VTA), independent of peripheral sources of progestogens, where it has potential actions at N-methyl-D-as
Externí odkaz:
https://doaj.org/article/0b646619a1be42bda9105b4110ea113a
Publikováno v:
American Journal of Men's Health, Vol 12 (2018)
Our research objective is to understand more, through subjective, self-reports on discussion boards/forums, persons’ experiences associated with the use of drugs that alter androgen metabolism, such as finasteride. Finasteride is an orally active,
Externí odkaz:
https://doaj.org/article/91f7b7af40424431a4821a35539e3e3b
Autor:
Sean C. Godar, Roberto Cadeddu, Gabriele Floris, Laura J. Mosher, Zhen Mi, David P. Jarmolowicz, Simona Scheggi, Alicia A. Walf, Carolyn J. Koonce, Cheryl A. Frye, Nancy A. Muma, Marco Bortolato
Publikováno v:
Biomolecules, Vol 9, Iss 11, p 749 (2019)
Finasteride (FIN) is the prototypical inhibitor of steroid 5α-reductase (5αR), the enzyme that catalyzes the rate-limiting step of the conversion of progesterone and testosterone into their main neuroactive metabolites. FIN is clinically approved f
Externí odkaz:
https://doaj.org/article/baf95fecf4604756a46e4525aef8e736
Autor:
Cheryl A. Frye, Vincent F. Lembo
Publikováno v:
Antioxidants-Benefits, Sources, Mechanisms of Action
One Health is a principle that takes into account the interactions of humans, animals, the surrounding environment, and how they affect each other. In order to examine this concept in an experimental paradigm, the effects and benefits of wild Alaskan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::682ba463caf103ea8d1e49bacd3cfe61
https://mts.intechopen.com/articles/show/title/one-health-and-the-positive-effects-of-alaskan-blueberries
https://mts.intechopen.com/articles/show/title/one-health-and-the-positive-effects-of-alaskan-blueberries
Publikováno v:
Frontiers in Systems Neuroscience, Vol 8 (2014)
A novel factor of interest for growth/plasticity in the brain is pregnane xenobiotic receptor (PXR). PXR is a liver factor known for its role in xenobiotic clearance and cholesterol metabolism. It is expressed in the brain, suggesting a potential rol
Externí odkaz:
https://doaj.org/article/cdd6ba9b47c7486ab1368137c52f426a