Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Cheryl Nickerson-Nutter"'
Autor:
Fenghua Zhang, Ehab A Ayaub, Bingbing Wang, Estela Puchulu‐Campanella, Yen‐Hsing Li, Suraj U Hettiarachchi, Spencer D Lindeman, Qian Luo, Sasmita Rout, Madduri Srinivasarao, Abigail Cox, Konstantin Tsoyi, Cheryl Nickerson‐Nutter, Ivan O Rosas, Philip S Low
Publikováno v:
EMBO Molecular Medicine, Vol 12, Iss 8, Pp 1-15 (2020)
Abstract Fibrotic diseases cause organ failure that lead to ~45% of all deaths in the United States. Activated macrophages stimulate fibrosis by secreting cytokines that induce fibroblasts to synthesize collagen and extracellular matrix proteins. Alt
Externí odkaz:
https://doaj.org/article/6c2ab7c60e9040ec977bb024e8f6c67b
Autor:
Yingwen Hu, Bingbing Wang, Jiayin Shen, Stewart A. Low, Karson S. Putt, Hans W. M. Niessen, Eric L. Matteson, Linda Murphy, Clemens Ruppert, Gerrit Jansen, Stephen J. Oliver, Yang Feng, Dimiter S. Dimitrov, Cheryl Nickerson-Nutter, Philip S. Low
Publikováno v:
Arthritis Research & Therapy, Vol 21, Iss 1, Pp 1-14 (2019)
Abstract Objectives Most therapies for autoimmune and inflammatory diseases either neutralize or suppress production of inflammatory cytokines produced by activated macrophages (e.g., TNFα, IL-1, IL-6, IL-17, GM-CSF). However, no approved therapies
Externí odkaz:
https://doaj.org/article/1dc2d4681dd3423db7d7c71fbd322d51
Autor:
Ehab A. Ayaub, Estela Puchulu-Campanella, Philip S. Low, Ivan O. Rosas, Spencer D. Lindeman, Yen Hsing Li, Jyoti Roy, Suraj U. Hettiarachchi, Fenghua Zhang, Cheryl Nickerson-Nutter, Xiaoliang Liang, Konstantin Tsoyi, Madduri Srinivasarao
Publikováno v:
Science Translational Medicine. 12
Idiopathic pulmonary fibrosis (IPF) is a lethal disease with an average life expectancy of 3 to 5 years. IPF is characterized by progressive stiffening of the lung parenchyma due to excessive deposition of collagen, leading to gradual failure of gas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79182dcfa797333ada3d0ba43ab56f50
https://doi.org/10.1126/scitranslmed.aay3724
https://doi.org/10.1126/scitranslmed.aay3724
Autor:
Ivan O. Rosas, Konstantin Tsoyi, Spencer D. Lindeman, Bingbing Wang, Abigail Cox, Fenghua Zhang, Suraj U. Hettiarachchi, Estela Puchulu-Campanella, Cheryl Nickerson-Nutter, Philip S. Low, Madduri Srinivasarao, Ehab A. Ayaub, Yen-Hsing Li, S. Rout
Publikováno v:
D109. MODULATING THE FIBROTIC RESPONSE.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9a89b9a9be32abbd76f25622ee89a6bc
https://doi.org/10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a7872
https://doi.org/10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a7872
Autor:
Cheryl Nickerson-Nutter, Ehab A. Ayaub, Yen-Hsing Li, Estela Puchulu-Campanella, Madduri Srinivasarao, Philip S. Low, Spencer D. Lindeman, Fenghua Zhang, Konstantin Tsoyi, Bingbing Wang, Suraj U. Hettiarachchi, Sasmita Rout, Abigail Cox, Ivan O. Rosas, Qian Luo
Publikováno v:
EMBO Molecular Medicine
EMBO Molecular Medicine, Vol 12, Iss 8, Pp n/a-n/a (2020)
EMBO Molecular Medicine, Vol 12, Iss 8, Pp n/a-n/a (2020)
Fibrotic diseases cause organ failure that lead to ~45% of all deaths in the United States. Activated macrophages stimulate fibrosis by secreting cytokines that induce fibroblasts to synthesize collagen and extracellular matrix proteins. Although sup
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d8ec9037972638af948a59b037c0d8c
https://pubmed.ncbi.nlm.nih.gov/32597014
https://pubmed.ncbi.nlm.nih.gov/32597014
Autor:
Stewart A. Low, Bingbing Wang, Eric L. Matteson, Philip S. Low, Karson S. Putt, Clemens Ruppert, Yingwen Hu, Jiayin Shen, Hans W.M. Niessen, Cheryl Nickerson-Nutter, Dimiter S. Dimitrov, Gerrit Jansen, Linda M. Murphy, Stephen J. Oliver, Yang Feng
Publikováno v:
Arthritis Research and Therapy, 21(1):143. BioMed Central
Arthritis Research & Therapy, Vol 21, Iss 1, Pp 1-14 (2019)
Arthritis Research & Therapy
Hu, Y, Wang, B, Shen, J, Low, S A, Putt, K S, Niessen, H W M, Matteson, E L, Murphy, L, Ruppert, C, Jansen, G, Oliver, S J, Feng, Y, Dimitrov, D S, Nickerson-Nutter, C & Low, P S 2019, ' Depletion of activated macrophages with a folate receptor-beta-specific antibody improves symptoms in mouse models of rheumatoid arthritis ', Arthritis Research and Therapy, vol. 21, no. 1, 143 . https://doi.org/10.1186/s13075-019-1912-0
Arthritis Research & Therapy, Vol 21, Iss 1, Pp 1-14 (2019)
Arthritis Research & Therapy
Hu, Y, Wang, B, Shen, J, Low, S A, Putt, K S, Niessen, H W M, Matteson, E L, Murphy, L, Ruppert, C, Jansen, G, Oliver, S J, Feng, Y, Dimitrov, D S, Nickerson-Nutter, C & Low, P S 2019, ' Depletion of activated macrophages with a folate receptor-beta-specific antibody improves symptoms in mouse models of rheumatoid arthritis ', Arthritis Research and Therapy, vol. 21, no. 1, 143 . https://doi.org/10.1186/s13075-019-1912-0
Objectives Most therapies for autoimmune and inflammatory diseases either neutralize or suppress production of inflammatory cytokines produced by activated macrophages (e.g., TNFα, IL-1, IL-6, IL-17, GM-CSF). However, no approved therapies directly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f86fea1408cd68a951029848818adc44
https://research.vumc.nl/en/publications/933709e3-08d8-4dcf-9eaa-7b43c4769024
https://research.vumc.nl/en/publications/933709e3-08d8-4dcf-9eaa-7b43c4769024
Autor:
Suraj U. Hettiarachchi, Spencer D. Lindeman, Yen-Hsing Li, Konstantin Tsoyi, Cheryl Nickerson-Nutter, Ivan O. Rosas, Estela Puchulu-Campanella, B. Athenson, Philip S. Low, Jyoti Roy, Madduri Srinivasarao, Fenghua Zhang
Publikováno v:
B103. ILD: THERAPY.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::05055bf21ed5eed9478fb0cf779fd654
https://doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a4087
https://doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a4087
Autor:
Mathilde Poussin, Cheryl Nickerson-Nutter, Daniel J. Powell, Prannda Sharma, J. Michael Robinson, Alba Rodriguez-Garcia, A.G. Roy
Publikováno v:
International Journal of Molecular Sciences; Volume 22; Issue 11; Pages: 5572
International Journal of Molecular Sciences, Vol 22, Iss 5572, p 5572 (2021)
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 5572, p 5572 (2021)
International Journal of Molecular Sciences
Folate receptor beta (FRβ) is a folate binding receptor expressed on myeloid lineage hematopoietic cells. FRβ is commonly expressed at high levels on malignant blasts in patients with acute myeloid leukemia (AML), as well as on M2 polarized tumor-a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ed656f20f6a67a1f67a39c224be4013
https://doi.org/10.3390/ijms22115572
https://doi.org/10.3390/ijms22115572
Autor:
Cheryl Nickerson-Nutter, Dean Messing, Nilufer P. Seth, Sean Keegan, John Douhan, Jason Edmonds, Timothy A. Cook, Stephen E. Benoit, Andrew L. Rankin, Varenka Rodriguez, Sarah Du, Micah J. Benson, Melanie Ruzek, Mark E. Schnute, Kyri Dunussi-Joannopoulos, David von Schack
Publikováno v:
The Journal of Immunology. 193:185-197
Inhibitors of Bruton’s tyrosine kinase (BTK) possess much promise for the treatment of oncologic and autoimmune indications. However, our current knowledge of the role of BTK in immune competence has been gathered in the context of genetic inactiva
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78e370ef582270e05a47f654d5c540f0
https://doi.org/10.4049/jimmunol.1302570
https://doi.org/10.4049/jimmunol.1302570
Autor:
Wim B. van den Berg, Cheryl Nickerson-Nutter, Fons A. J. van de Loo, Renoud J. Marijnissen, Deborah Young, Sabrina Garcia de Aquino, Annemieke M. H. Boots, Debbie M. Roeleveld, Shahla Abdollahi-Roodsaz, Annemiek B. van Spriel, Marije I. Koenders
Publikováno v:
Arthritis & Rheumatology. 66:886-895
OBJECTIVE: The cytokine interleukin-21 (IL-21) can have both proinflammatory and immunosuppressive effects. The purpose of this study was to investigate the potential dual role of IL-21 in experimental arthritis in relation to Th17 cells. METHODS: An
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c6c34a2dee1ffb43c53e84d803aab10c
https://doi.org/10.1002/art.38312
https://doi.org/10.1002/art.38312