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pro vyhledávání: '"Cherukury, Madhu"'
Akademický článek
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Akademický článek
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Autor:
David F. Woodward, Du-Shieng Chien, Thai G. Nguyen, Diane D.-S. Tang-Liu, Cherukury Madhu, Peter Rix
Publikováno v:
Journal of Ocular Pharmacology and Therapeutics. 14:389-399
The objective of this study was to assess the corneal and scleral permeabilities of natural prostaglandins as well as their prodrugs and analogs through human cornea and sclera in vitro. The "apparent permeability coefficients" (Papp) of natural pros
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0dc8f47c4dcd3f49b53565cb33d3b88f
https://doi.org/10.1089/jop.1998.14.389
https://doi.org/10.1089/jop.1998.14.389
Publikováno v:
Environmental Toxicology and Pharmacology. 3:251-256
The suitability of a dynamic lung slice culture system as an in vitro model for studying pulmonary metabolism of PGF 2 α was assessed. [ 3 H]Prostaglandin F 2 α ([ 3 H]PGF 2 α ), a twenty carbon fatty acid that contains a five-carbon ring and is k
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b960184f17e1f42387c4f3d011ce6f13
https://doi.org/10.1016/s1382-6689(97)00020-3
https://doi.org/10.1016/s1382-6689(97)00020-3
Publikováno v:
Journal of Pharmaceutical Sciences. 85:415-418
This study was designed to examine the effect of benzalkonium chloride/ethylenediaminetetraacetic acid (BAK/EDTA) on the ocular bioavailability (Focular) of ketorolac tromethamine after ocular instillation to normal and de-epithelialized corneas of r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cdb7c8556d44629d3d2e1674bc7452b
https://doi.org/10.1021/js9504189
https://doi.org/10.1021/js9504189
Publikováno v:
Toxicology and Applied Pharmacology. 117:233-241
Paraquat, a frequently used contact herbicide, produces oxidative stress by undergoing redox cycling and generating reactive oxygen species. Paraquat is also effective at increasing hepatic levels of metallothionein (MT). The mechanism(s) by which ag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7404297d5cfcad81c18a652201522ada
https://doi.org/10.1016/0041-008x(92)90242-k
https://doi.org/10.1016/0041-008x(92)90242-k
Publikováno v:
Toxicology and Applied Pharmacology. 115:191-198
Recently, we demonstrated that a microsomal enzyme inducer with a steroidal structure, pregnenolone-16 alpha-carbonitrile (PCN), markedly decreased the hepatotoxicity of acetaminophen (AA) in hamsters. Therefore, it was of interest to determine if PC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6c6c7da7ba1cb575e7fa83d95b8661e
https://doi.org/10.1016/0041-008x(92)90323-k
https://doi.org/10.1016/0041-008x(92)90323-k
Autor:
Cherukury Madhu, Curtis D. Klaassen
Publikováno v:
Toxicology Letters. 60:227-236
This investigation was designed to determine whether biliary excretion of bromobenzene(BB)-glutathione(GSH) conjugate can be used as an index of in vivo activation of BB. In order to test this hypothesis, the effect of chemicals known to alter the to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbc4a9fadd9e63142c1ddb6860452a8c
https://doi.org/10.1016/0378-4274(92)90278-r
https://doi.org/10.1016/0378-4274(92)90278-r
Publikováno v:
Journal of Chromatography B: Biomedical Sciences and Applications. 574:146-149
The application of controlled-flow anion chromatography to assay inorganic sulfate in biological fluids and tissues is described. The eluent used in previous methods for analyzing sulfate in biological fluids has been modified by adding 4.5% acetonit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3afe1c307680f440d9a7354fdcbe19bf
https://doi.org/10.1016/0378-4347(92)80110-c
https://doi.org/10.1016/0378-4347(92)80110-c
Autor:
Curtis D. Klaassen, Cherukury Madhu
Publikováno v:
Toxicology and Applied Pharmacology. 109:305-313
Overdosage of acetaminophen (AA) is known to produce acute liver toxicity in both humans and laboratory animals. Hamsters are especially sensitive to the hepatotoxic effect of AA. In the present study, hamsters pretreated with pregnenolone-16α-carbo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::18f4794b1d43734e6c89351a00c2188c
https://doi.org/10.1016/0041-008x(91)90177-g
https://doi.org/10.1016/0041-008x(91)90177-g