Zobrazeno 1 - 10
of 105
pro vyhledávání: '"Cherry L, Herald"'
Autor:
Cherry L. Herald, Rui Tan, Jean-Charles Chapuis, Larry P. Tackett, Denise Nielsen Tackett, Jiang Du, Jean M. Schmidt, Toshihiko Nogawa, Justin Searcy, Qinghua Ye, Animesh Goswami, Gordon M. Cragg, John N. A. Hooper, Michael S. Hoard, Lee Williams, Dennis L. Doubek, Robin K. Pettit, Felicia M. Craciunescu, Fiona Hogan, George R. Pettit, Zbigniew A. Cichacz, Jun-Ping Xu
Publikováno v:
Journal of Natural Products. 71:438-444
Bioassay-guided fractionation of extracts of various plants, marine organisms, and microorganisms has led to the discovery of new natural sources of a number of known compounds that have significant biological activity. The isolation of interesting a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2d5b60ce5fc1ae387985d7ee5ca6ac5f
https://doi.org/10.1021/np700738k
https://doi.org/10.1021/np700738k
Autor:
John C. Knight, Cherry L. Herald, Gordon M. Cragg, Jean-Charles Chapuis, Delbert L. Herald, Venugopal J. R. V. Mukku, George R. Pettit
Publikováno v:
Journal of Natural Products. 71:130-133
An investigation of the Phillippine Ampelocissus sp. roots for cancer cell growth inhibitory components led to the isolation of a new acetogenin characterized as 22-epicalamistrin (1) employing primarily 2D NMR and high-resolution mass spectral analy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f03117f94bbdc0fd757f522445aef506
https://doi.org/10.1021/np068050q
https://doi.org/10.1021/np068050q
Autor:
Tanja Woyke, Zbigniew A. Cichacz, Robin K. Pettit, Cherry L. Herald, George R. Pettit, Sandy Pon
Publikováno v:
Medical Mycology. 43:453-463
Spongistatin 1 is a macrocyclic lactone polyether from the marine sponge Hyrtios erecta. The aim of this study was to evaluate the in vitro and in vivo antifungal efficacies and mechanism of spongistatin 1. Spongistatin 1 was fungicidal for the major
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c18cbcb13b89e52a78d08800688f44c
https://doi.org/10.1080/13693780500050598
https://doi.org/10.1080/13693780500050598
Autor:
Yoshiaki Kamano, Toshihiko Nogawa, Ayano Kotake, Hatsue Hiraide, Cherry L. Herald, George R. Pettit
Publikováno v:
Journal of Liquid Chromatography & Related Technologies. 23:399-409
The Separation of bryostatin derivatives (26-acetate, 26-metabromobenzoate, 26-ketone, and 13→ 30 epoxide) by high performance liquid chromatography (HPLC) using normal phase and reverse phase systems was accomplished. Using n-hexane/EtOAc/MeOH/H2O
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9bc4c06947825c8657ebaf71f18ec8b9
https://doi.org/10.1081/jlc-100101459
https://doi.org/10.1081/jlc-100101459
Autor:
George R. Pettit, Yoshiaki Kamano, Delbert L. Herald, Hideji Itokawa, Cherry L. Herald, Hui-ping Zhang, Osamu Shirota, Hiroshi Morita
Publikováno v:
Tetrahedron. 52:2369-2376
Conformation of bryostatin 10, a marine antineoplastic macrolide, in CDCl3 was analyzed by the spectroscopic and computational chemical methods. A combination of homonuclear two-dimensional NMR techniques at 600 MHz have enabled us to perform complet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1eb51ae9dd864bdaac657c6fa0e0e5ab
https://doi.org/10.1016/0040-4020(95)01080-7
https://doi.org/10.1016/0040-4020(95)01080-7
Autor:
Yoshiaki Kamano, Jean-Charles Chapuis, John C. Coll, George R. Pettit, Jean M. Schmidt, Peter M. Blumberg, F. Gao, Cherry L. Herald, Nancy E. Lewin
Publikováno v:
Journal of Natural Products. 59:286-289
Separation of two trace cancer cell growth inhibitory (P388 leukemia) fractions from about 1000 kg of wet Gulf of Mexico Bugula neritina (Bryozoa) has led to the isolation of bryostatins 16-18 (2-4). A combination of HRFABMS and high-field (400 MHz)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b0780ae2f63be406d391b959d4cb9dc
https://doi.org/10.1021/np960100b
https://doi.org/10.1021/np960100b
Autor:
George F. Taylor, George R. Pettit, Zbigniew A. Cichacz, Cherry L. Herald, Ernest Hamel, John A. Kepler, Ruoli Bai
Publikováno v:
Biochemistry. 34:9714-9721
The highly cytotoxic, sponge-derived, antimitotic macrolide polyether spongistatin 1 has been previously shown to inhibit microtubule assembly, the binding of vinblastine and GTP to tubulin, and displacement of GDP bound in the exchangeable site of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72512089cf388b4d2c0a75f69310c640
https://doi.org/10.1021/bi00030a009
https://doi.org/10.1021/bi00030a009
Autor:
Cherry L. Herald, Zbigniew A. Cichacz, Mary Carmen Roach, Veena Prasad, George R. Pettit, Richard F. Ludueña
Publikováno v:
Drug Development Research. 35:40-48
Macrocyclic lactone polyethers of marine origin include a series of compounds which bind to tubulin, the subunit protein of microtubules, and inhibit microtubule assembly and vinblastine binding to tubulin. We have previously studied two of these com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::76fd74c2782d0d7617c28322fc663712
https://doi.org/10.1002/ddr.430350107
https://doi.org/10.1002/ddr.430350107
Antineoplastic Agents 293. The Exceptional Human Cancer Cell Growth Inhibitors Spongistatins 6 and 7
Autor:
George R. Pettit, Jean M. Schmidt, Michael R. Boyd, Nigel D. Christie, Zbigniew A. Cichacz, Cherry L. Herald, Feng Gao
Publikováno v:
Natural Product Letters. 3:239-244
A twenty year investigation of the South African marine sponge Spirastrella spinispirulifera (Carter, 1879) for antineoplastic constituents has now led to discovery of spongistatin 6 (1e) and 7 (2b) in 3.5 × 10−7% and 2.2 × 10−7% yields. Struct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0da5968dd3b42a057b8ecea6f40daa47
https://doi.org/10.1080/10575639308043871
https://doi.org/10.1080/10575639308043871
Autor:
Haruhisa Kizu, Jean-Charles Chapuis, Dennis L. Doubek, Cherry L. Herald, Jean M. Schmidt, Fred E. Boettner, Michael R. Boyd, Yoshiaki Kamano, Claude Michel, George R. Pettit, Youichi Fujii
Publikováno v:
Tetrahedron. 49:9151-9170
A twenty year pursuit of the cell growth inhibitory and antineoplastic constituents of the Western Indian Ocean (Mauritius) sea hare Dolabella auricularia has resulted in the discovery of fifteen structurally unique peptide, cyclopeptide, depsipeptid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::920e9aeaa7defa63f163449c7a424f6b
https://doi.org/10.1016/0040-4020(93)80003-c
https://doi.org/10.1016/0040-4020(93)80003-c