Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Cherry Ee Lin, Ng"'
Autor:
Cai Ping Koh, Avinash Govind Bahirvani, Chelsia Qiuxia Wang, Tomomasa Yokomizo, Cherry Ee Lin Ng, Linsen Du, Vinay Tergaonkar, Dominic Chih-Cheng Voon, Hiroaki Kitamura, Hiroki Hosoi, Takashi Sonoki, Mok Meng Huang Michelle, Lii Jye Tan, Akiko Niibori-Nambu, Yi Zhang, Archibald S. Perkins, Zakir Hossain, Daniel G. Tenen, Yoshiaki Ito, Byrappa Venkatesh, Motomi Osato
Publikováno v:
Gene. 851:147049
A cis-regulatory genetic element which targets gene expression to stem cells, termed stem cell enhancer, serves as a molecular handle for stem cell-specific genetic engineering. Here we show the generation and characterization of a tamoxifen-inducibl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf8e1e2f6ef13f4828e21c4e4419664f
https://doi.org/10.1016/j.gene.2022.147049
https://doi.org/10.1016/j.gene.2022.147049
Autor:
Cherry Ee Lin Ng, Daniel G. Tenen, Cai Ping Koh, Takashi Sonoki, Vinay Tergaonkar, Yi Zhang, Archibald S. Perkins, Avinash Govind Bahirvani, Zakir Hossain, Linsen Du, Byrappa Venkatesh, Tomomasa Yokomizo, Chelsia Qiuxia Wang, Akiko Niibori-Nambu, Motomi Osato, Yoshiaki Ito, Hiroki Hosoi, Dominic Chih-Cheng Voon, Michelle Meng Huang Mok
SummaryA cis-regulatory genetic element which targets gene expression to stem cells, termed stem cell enhancer, serves as a molecular handle for stem cell-specific genetic engineering. Here we show the generation and characterization of a tamoxifen-i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::25c73b879a353eafa22afa7a90687302
https://doi.org/10.1101/2021.11.24.469958
https://doi.org/10.1101/2021.11.24.469958
Autor:
Vinay Tergaonkar, Marito Araki, Chelsia Qiuxia Wang, Cherry Ee Lin Ng, Yoshiaki Ito, Gang Huang, Motomi Osato, C P Koh
Publikováno v:
Leukemia. 27:1793-1802
A broad range of human leukemias carries RUNX1 and MLL genetic alterations. Despite such widespread involvements, the relationship between RUNX1 and MLL has never been appreciated. Recently, we showed that RUNX1 physically and functionally interacts
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1ec15160d814eddf2b5537554d3c8a5
https://doi.org/10.1038/leu.2013.200
https://doi.org/10.1038/leu.2013.200
Autor:
Cherry Ee Lin Ng, Zilong Wen, Branko Cirovic, Motomi Osato, Tomomasa Yokomizo, Hao Jin, Namiko Yamashita, Yoshiaki Ito
Publikováno v:
Stem Cells. 28:1869-1881
Runx1 is essential for the generation of hematopoietic stem cells (HSCs) and is frequently mutated in human leukemias. However, the cis-regulatory mechanisms modulating the Runx1 gene expression remain to be elucidated. Herewith, we report the identi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb6a145cf4e7d9ad304fb3e7d72eef6d
https://doi.org/10.1002/stem.507
https://doi.org/10.1002/stem.507
Publikováno v:
Critical Reviews in Oncology/Hematology. 71:1-11
Transcription in multicellular eukaryotic organisms involves an elaborate orchestration of the core promoter and cis-regulatory elements to drive spatiotemporally and quantitatively correct gene expression. Unlike promoters found immediately upstream
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13acfa9c96df80a0c9080dfc74a77ef4
https://doi.org/10.1016/j.critrevonc.2008.10.008
https://doi.org/10.1016/j.critrevonc.2008.10.008
Autor:
Cai Ping, Koh, Cherry Ee Lin, Ng, Giselle Sek Suan, Nah, Chelsia Qiuxia, Wang, Vinay, Tergaonkar, Takayoshi, Matsumura, Tomomasa, Yokomizo, Toshio, Suda, Motomi, Osato
Publikováno v:
Histology and histopathology. 30(6)
There has been considerable interest in identifying a cis-regulatory element that targets gene expression to stem cells. Such an element, termed stem cell enhancer, holds the promise of providing important insights into the transcriptional programs r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9f53030d362742707b8aecc04514c55f
https://pubmed.ncbi.nlm.nih.gov/25574754
https://pubmed.ncbi.nlm.nih.gov/25574754
Autor:
Bor Luen Tang, Cherry Ee Lin Ng
Publikováno v:
Journal of Neuroscience Research. 67:559-565
The recently cloned gene Nogo, whose alternative splice products correspond to the antigenic target of the central nervous system (CNS) regeneration enhancing monoclonal antibody IN-1, codes for membrane proteins enriched in brain, particularly in ol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fedae61ed6b387e086b9d4f02c75d82
https://doi.org/10.1002/jnr.10134
https://doi.org/10.1002/jnr.10134
Autor:
Jenny Chang, Scott A. Armstrong, Demetrios Kalaitzidis, Andrei V. Krivtsov, Amit U. Sinha, Stuart Dias, Cherry Ee Lin Ng
The targeting of self-renewal pathways commonly activated in leukemia serves as a potential strategy for multiple subtypes of this disease regardless of genetic, clonal, or cellular heterogeneity. Elevation of β-catenin above physiological condition
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c11e6aef77e241a93e9aee38d535238f
https://europepmc.org/articles/PMC4367949/
https://europepmc.org/articles/PMC4367949/
Publikováno v:
Blood, 117(23), 6132-6134. American Society of Hematology
Hematopoietic cell clusters associated with the midgestation mouse aorta, umbilical and vitelline arteries play a pivotal role in the formation of the adult blood system. Both genetic and live-imaging data indicate that definitive hematopoietic proge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::715953dc25376fb933d5ae00ff74dc03
https://pure.eur.nl/en/publications/4b14df51-9200-4c6e-bce8-bcc11c623a90
https://pure.eur.nl/en/publications/4b14df51-9200-4c6e-bce8-bcc11c623a90
Publikováno v:
Gene. 399(2)
The Runx family genes are involved in hematopoiesis, osteogenesis and neuropoiesis, and mutations in these genes have been frequently associated with human hereditary diseases and cancers. Here we report the cDNA cloning of the full Runx gene family
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49d5d4fa21a29b57b7cb346cea3cd6a1
https://pubmed.ncbi.nlm.nih.gov/17604919
https://pubmed.ncbi.nlm.nih.gov/17604919