Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Cherry C Chen"'
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e108880 (2014)
Central nervous system (CNS) diseases are difficult to treat because of the blood-brain barrier (BBB), which prevents most drugs from entering into the brain. Intranasal (i.n.) administration is a promising approach for drug delivery to the brain, by
Externí odkaz:
https://doaj.org/article/48a6b2f3216b411fad702c73bb100132
Autor:
Manuel Bernal, Maria Eleni Karakatsani, Carlos Sierra, Shih-Ying Wu, Cherry C. Chen, Elisa E. Konofagou, Camilo Acosta
Publikováno v:
Journal of Cerebral Blood Flow & Metabolism. 37:1236-1250
Focused ultrasound in conjunction with lipid microbubbles has fully demonstrated its ability to induce non-invasive, transient, and reversible blood–brain barrier opening. This study was aimed at testing the feasibility of our lipid-coated microbub
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b17954cd256e0eeffddfe450fe4c31f
https://doi.org/10.1177/0271678x16652630
https://doi.org/10.1177/0271678x16652630
Autor:
Virginie Papadopoulou, Wenlan Zheng, Christopher B. Arena, Paul A. Dayton, Anthony Novell, Cherry C. Chen, Elisa E. Konofagou, Samantha M. Fix, Shih-Ying Wu, Oluyemi Olumolade
Publikováno v:
2017 IEEE International Ultrasonics Symposium (IUS).
Focused ultrasound with nanodroplets could facilitate localized drug delivery after vaporization with potentially improved in vivo stability, drug payload, and minimal interference outside of the focal zone compared with microbubbles. While the feasi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::501ef759f9892545154605ae1a353a0e
https://doi.org/10.1109/ultsym.2017.8091719
https://doi.org/10.1109/ultsym.2017.8091719
Autor:
Oluyemi Olumolade, Christopher B. Arena, Wenlan Zheng, Shih-Ying Wu, Virginie Papadopoulou, Paul A. Dayton, Cherry C. Chen, Elisa E. Konofagou, Samantha M. Fix
Publikováno v:
2017 IEEE International Ultrasonics Symposium (IUS).
Acoustically-activated nanodroplets facilitate localized drug delivery after vaporization with improved in vivo stability, drug payload, and minimal interference outside of the ultrasound focal zone compared with microbubbles. They are new acoustic m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5c75819d0792c42e10eb1eb51bea2b04
https://doi.org/10.1109/ultsym.2017.8092117
https://doi.org/10.1109/ultsym.2017.8092117
Publikováno v:
Ultrasound in Medicine & Biology. 38:492-503
Ultrasound molecular imaging is a powerful diagnostic modality employing microbubbles coated with targeting ligands specific for endothelial biomarkers. The circulation persistence of ligand-bearing contrast agents is a key determinant in their contr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4930200c4c3961f1dc117aaa7806fd33
https://doi.org/10.1016/j.ultrasmedbio.2011.12.007
https://doi.org/10.1016/j.ultrasmedbio.2011.12.007
Autor:
Cherry C. Chen, Mark A. Borden
Publikováno v:
Biomaterials. 32:6579-6587
Complement fixation to surface-conjugated ligands plays a critical role in determining the fate of targeted colloidal particles after intravenous injection. In the present study, we examined the immunogenicity of targeted microbubbles with various su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b851f0cbb3dd95a838ac920ea41009a8
https://doi.org/10.1016/j.biomaterials.2011.05.027
https://doi.org/10.1016/j.biomaterials.2011.05.027
Autor:
Mark A. Borden, Cherry C. Chen
Publikováno v:
Langmuir. 26:13183-13194
Using microbubbles as model systems, we examined molecular diffusion and binding to colloidal surfaces in a bimodal PEG brush layers. A microbubble is a gaseous colloidal particle with diameter less than 10 μm, of which the surface comprises amphiph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86138d5f15afabb3475ed6f6b8be48aa
https://doi.org/10.1021/la101796p
https://doi.org/10.1021/la101796p
Autor:
Samantha M. Fix, Oluyemi Olumolade, Christopher B. Arena, Cherry C. Chen, Anthony Novell, Shih-Ying Wu, Paul A. Dayton, Virginie Papadopoulou, Elisa E. Konofagou, Wenlan Zheng
Publikováno v:
Physics in Medicine & Biology. 63:035002
Focused ultrasound with nanodroplets could facilitate localized drug delivery after vaporization with potentially improved in vivo stability, drug payload, and minimal interference outside of the focal zone compared with microbubbles. While the feasi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f75768a137e6c1085d3c8d8a398e6ed
https://doi.org/10.1088/1361-6560/aaa30d
https://doi.org/10.1088/1361-6560/aaa30d
Autor:
Camilo Acosta, Gesthimani Samiotaki, Shutao Wang, Tao Sun, Cherry C. Chen, Elisa E. Konofagou
Publikováno v:
Physics in medicine and biology. 60(23)
Cavitation events seeded by microbubbles have been previously reported to be associated with MR- or fluorescent-contrast enhancement after focused ultrasound (FUS)-induced blood-brain barrier (BBB) opening. However, it is still unknown whether bubble
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ad35f300e29da1f47f48fc54f1ed702
https://pubmed.ncbi.nlm.nih.gov/26562661
https://pubmed.ncbi.nlm.nih.gov/26562661
Publikováno v:
2015 IEEE International Ultrasonics Symposium (IUS).
Lipid-shelled microbubbles have been used in ultrasound-mediated drug delivery. The physicochemical properties of the microbubble shell could affect the delivery efficiency since they determine the microbubble mechanical properties, circulation persi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d5e6af20e7cd177f7c7adc7ce6b320cb
https://doi.org/10.1109/ultsym.2015.0100
https://doi.org/10.1109/ultsym.2015.0100