Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Cherokee S. Hoaglund Hyzer"'
Autor:
Cherokee S. Hoaglund Hyzer, Bruno Catacchio, Donnie Pulliam, Mingkun Fu, Chait Wannere, Yelizaveta Babayan, Allison L. Dill, Eric Adamec, Megan McMahon, Fenghe Qiu, Angela Coon, Robert Timpano, Lars Gruenig, Karina Szymulanska-Ramamurthy, Michael Lesslie, Brian P. Regler
Publikováno v:
Journal of Pharmaceutical Innovation. 16:566-574
Purpose Lean stability is a science- and risk-based initiative which utilizes the enhanced understanding of drug substance and drug product physical and chemical characteristics to (1) reduce and optimize the design of standard stability protocols; (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4437b626ad512d2419274099ad60dd05
https://doi.org/10.1007/s12247-020-09463-z
https://doi.org/10.1007/s12247-020-09463-z
Autor:
Anjali Agrawal, Stan Altan, Steven W. Baertschi, Chandan Bhugra, Ricardo Borjas, John Campbell, Dana Carabillo, Juan Chen, Lilan H. Chen, Donald Clancy, Elise Clement, Stephen T. Colgan, David Curran, Gena Dalziel, Mayur Dudhedia, Sudharsan Dwaraknath, Anita L. Freed, Paul Gerst, Michael Hawley, Evan M. Hetrick, Cherokee S. Hoaglund Hyzer, Gordon Hutton, Madhuri Jerfy, Satish Kamath, Ammar Khawam, Todd Lewis, Hanlin Li, Julie Lippke, Bruce C. MacDonald, Llurellyn Malcolm, Keith Masse, Tony Mazzeo, Andrew P. Monahan, Ewa Nauka, Rachel Orr, Brian W. Pack, Jeegna Patel-Jones, Jackson D. Pellett, William R. Porter, Fenghe Qiu, Jeffrey C. Roberts, Samantha Rusk, Kevin O. Ryan, Kevin Ryan, Robert Schwabe, Garry Scrivens, Ashish Soman, Jon T. Swanson, Zhixin Jessica Tan, Martyn Ticehurst, Robert J. Timpano, Bryan S. Wicks, Zeena Williams, Chad N. Wolfe, Gavin Wood, Zufan Steven Wu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ddf3d76a1a8cc8978d2bef65c0f977b9
https://doi.org/10.1016/b978-0-12-802786-8.09988-5
https://doi.org/10.1016/b978-0-12-802786-8.09988-5
Publikováno v:
TrAC Trends in Analytical Chemistry. 49:126-136
Mass balance is an important concept in pharmaceutical development, but it often proves challenging to assess accurately. This article explores the various methods by which mass balance can and should be measured, expressed, and evaluated in conjunct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3291043b75368e531b37baeb27211ddd
https://doi.org/10.1016/j.trac.2013.06.006
https://doi.org/10.1016/j.trac.2013.06.006
Autor:
Michele L. Williamson, R. Brian Scherer, Steven W. Baertschi, Michael E. Kopach, Cherokee S. Hoaglund Hyzer, Patrick J. Jansen
Publikováno v:
Journal of pharmaceutical sciences. 106(5)
Edivoxetine (LY2216684 HCl), although a chemically stable drug substance, has shown the tendency to degrade in the presence of carbohydrates that are commonly used tablet excipients, especially at high excipient:drug ratios. The major degradation pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67d67cdd9856f27cea2b8c161ab3ebf9
https://pubmed.ncbi.nlm.nih.gov/28159638
https://pubmed.ncbi.nlm.nih.gov/28159638
Publikováno v:
Molecular pharmaceutics. 12(10)
In this work, we discuss leveraging the Biopharmaceutics Classification System (BCS) in the development of edivoxetine HCl, a selective norepinephrine reuptake inhibitor. First, the biopharmaceutical and in vivo data are presented and discussed. Solu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e974e47425de6c39df6cf814017e4c7
https://pubmed.ncbi.nlm.nih.gov/26365521
https://pubmed.ncbi.nlm.nih.gov/26365521
Publikováno v:
Analytical Chemistry. 73:6000-6007
A new technique for studying the time dependence of conformational changes of gas-phase protein ions is described. In this approach, a short pulse of electrosprayed protein ions is introduced into an ion trap and stored. After a defined time period,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6257be52d6b93926892d79504da07ac4
https://doi.org/10.1021/ac010744a
https://doi.org/10.1021/ac010744a
Publikováno v:
Analytical Chemistry. 72:2737-2740
An ion mobility/mass spectrometry technique has been developed to record collision-induced dissociation patterns for multiple ions in a parallel fashion. In this approach, a mixture of ions is separated in a drift tube on the basis of differences in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33dd705400949299cffe653c39d2e6e1
https://doi.org/10.1021/ac0000170
https://doi.org/10.1021/ac0000170
Publikováno v:
Chemical Reviews. 99:3037-3080
The recent development of electrospray ionization (ESI)1 and matrix-assisted laser desorption ionization (MALDI)2 sources for creation of macromolecular ions has brought about a renaissance in the field of mass spectrometry (MS). It is now common to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e13a208c7781baae57b081940010a62
https://doi.org/10.1021/cr980139g
https://doi.org/10.1021/cr980139g
Publikováno v:
The Journal of Physical Chemistry B. 103:1203-1207
Cross sections for mixtures of tryptic digest peptide ions formed by electrospray ionization have been measured by a new ion mobility/time-of-flight mass spectrometry technique. Analysis of a series of 113 peptides containing 5−10 residues and havi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9407f3fcc1fe80b0a3376268c3131f97
https://doi.org/10.1021/jp983906o
https://doi.org/10.1021/jp983906o
Publikováno v:
ChemInform. 30
The recent development of electrospray ionization (ESI)1 and matrix-assisted laser desorption ionization (MALDI)2 sources for creation of macromolecular ions has brought about a renaissance in the field of mass spectrometry (MS). It is now common to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b5601c085d3ce0a7a4ee04fe55784ab5
https://doi.org/10.1002/chin.199950299
https://doi.org/10.1002/chin.199950299