Thromboelastographic study of fibrin clot and molecular basis of maximum clot firmness

Autor: V. I. Gryshchuk, Y. M. Stohnii, Chernyshenko Tm, V. O. Chernyshenko, S. I. Zhuk, O. I. Ivashchenko, K. P. Klymenko, O. M. Platonov, D S Korolova, O. P. Kostiuchenko, I. V. Us

Publikováno v: Ukrainian Biochemical Journal, Vol 93, Iss 2, Pp 62-70 (2021)

Maximum clot firmness (MCF) is the main parameter of thromboelastography (TEG) reflecting the stability of a clot. In this work, we looked for markers that can influence the enhancement of MCF and detec­ted molecular markers and blood clotting param

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d548bd37b2d2ee5140b403e032fc18b2
http://ukrbiochemjournal.org/wp-content/uploads/2021/05/Korolova_2_21.pdf

Blood coagulation parameters in rats with acute radiation syndrome receiving activated carbon as a preventive remedy

Autor: Platonova Tn, M. Mazur, Chernyshenko Tm, O. Sydorenko, E.A. Snezhkova, V. O. Chernyshenko, V. G. Nikolaev, E. V. Lugovskoy

Publikováno v: The Ukrainian Biochemical Journal
Ukrainian Biochemical Journal, Vol 91, Iss 2, Pp 52-62 (2019)

Radiation-induced coagulopathy (RIC) is one of the major causes of death during acute radiation syndrome (ARS). The aim of this study was to characterize the responses of the hemostasis system to ARS of a moderate level on the 1st and 9th days after

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cf78199c4db80bedf23019691cb7b61
https://doi.org/10.15407/ubj91.02.052

Antiplatelet and anti-proliferative action of disintegrin from Echis multisquamatis snake venom

Autor: Liudmyla V. Garmanchuk, E. V. Lugovskoy, Platonova Tm, V. O. Chernyshenko, Chernyshenko Tm, Ludmila Kasatkina, O. V. Gornytska, O. I. Dzhus, D S Korolova, Natalia Petruk, Andriy Rebriev

Publikováno v: Croatian Medical Journal

Aim To purify the platelet aggregation inhibitor from Echis multisquamatis snake venom (PAIEM) and characterize its effect on platelet aggregation and HeLa cell proliferation. Methods Sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAG

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1eafbcd9602cb2c66af748d019c6d1e4
https://doi.org/10.3325/cmj.2017.58.118

The Rise of Factor X Level in Blood Plasma of Patients at Severe Burn Injuries.

Autor: Kozynets GP; Shupyk National Medical Academy of Postgraduate Education of Ministry of Health of Ukraine, Kyiv, Ukraine., Tsyhankov VP; Shupyk National Medical Academy of Postgraduate Education of Ministry of Health of Ukraine, Kyiv, Ukraine., Korolova DS; Protein Structure and Functions department, Palladin Institute of Biochemistry of NAS of Ukraine, Kyiv, Ukraine., Gornytska OV; Protein Structure and Functions department, Palladin Institute of Biochemistry of NAS of Ukraine, Kyiv, Ukraine., Savchuk OM; ESC 'Institute of Biology and Medicine', Kyiv, Ukraine., Chernyshenko VO; Protein Structure and Functions department, Palladin Institute of Biochemistry of NAS of Ukraine, Kyiv, Ukraine., Chernyshenko TM; Protein Structure and Functions department, Palladin Institute of Biochemistry of NAS of Ukraine, Kyiv, Ukraine., Platonova TM; Protein Structure and Functions department, Palladin Institute of Biochemistry of NAS of Ukraine, Kyiv, Ukraine.

Publikováno v: Journal of burn care & research : official publication of the American Burn Association [J Burn Care Res] 2022 Jul 01; Vol. 43 (4), pp. 965-970.

Non-enzymatic activation of prothrombin induced by interaction with fibrin β26-42 region

Autor: V. O. Chernyshenko, Iryna N Kolesnikova, Galyna P Volynets, E. V. Lugovskoy, Chernyshenko Tm, D S Korolova, Platonova Tm

Publikováno v: Acta Biochimica Polonica. 62:517-522

We have discovered that addition of monomeric desAB fibrin to prothrombin leads to appearance of the thrombin-like activity of prothrombin towards S2238 chromogenic substrate. DesA and desABβ(15-42)2 fibrin forms did not cause any activation of prot

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2000e4360bf7e23e8c46711be0e21526
https://doi.org/10.18388/abp.2014_896