Zobrazeno 1 - 10
of 116
pro vyhledávání: '"Chern Ein, Oon"'
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 13, Iss 2, Pp 478-497 (2023)
Cancer is the second leading cause of mortality globally which remains a continuing threat to human health today. Drug insensitivity and resistance are critical hurdles in cancer treatment; therefore, the development of new entities targeting maligna
Externí odkaz:
https://doaj.org/article/829e97be37704bb78e3b662fdbe2117a
Autor:
Soundararajan Vijayarathna, Chern Ein Oon, Majid Al-Zahrani, Muyassar H. Abualreesh, Yeng Chen, Jagat R. Kanwar, Sumaira Sahreen, Shakira Ghazanfar, Mohd Adnan, Sreenivasan Sasidharan
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Polyalthia longifolia var. angustifolia Thw. (Annonaceae), is a famous traditional medicinal plant in Asia. Ample data specifies that the medicinal plant P. longifolia has anticancer activity; however, the detailed mechanisms of action still need to
Externí odkaz:
https://doaj.org/article/f880068e4d3d43198a942c7a7eb8d835
Publikováno v:
Biomedicines, Vol 11, Iss 11, p 3059 (2023)
Growing evidence has highlighted that mitochondrial dysfunction contributes to drug-induced toxicities and leads to drug attrition and post-market withdrawals. The acetylation or deacetylation of mitochondrial proteins can affect mitochondrial functi
Externí odkaz:
https://doaj.org/article/c6c2dd7d63844d9fa342a90fa379bc79
Autor:
Azka Ainun Nisaa, Chern-Ein Oon, Sasidharan Sreenivasan, Venugopal Balakrishnan, Deepa Rajendran, Jun-Jie Tan, Fatin Fazrina Roslan, Svetoslav Dimitrov Todorov, Woo-Sik Jeong, Feiyan Zhao, Nur Syafiqah Mohamad Nasir, Zakuan Zainy Deris, Heping Zhang, Yong-Ha Park, Guoxia Liu, Min-Tze Liong
Publikováno v:
Preventive Nutrition and Food Science. 28:1-9
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1cd0903a915dd7f2751c5eed201520e7
https://doi.org/10.3746/pnf.2023.28.1.1
https://doi.org/10.3746/pnf.2023.28.1.1
Autor:
Pravena Ramachandran, Boon-Keat Khor, Chong Yew Lee, Ruey-An Doong, Chern Ein Oon, Nguyen Thi Kim Thanh, Hooi Ling Lee
Publikováno v:
Biomedicines, Vol 10, Iss 2, p 421 (2022)
Titanium dioxide nanoparticles (TiO2 NPs) have been proven to be potential candidates in cancer therapy, particularly photodynamic therapy (PDT). However, the application of TiO2 NPs is limited due to the fast recombination rate of the electron (e−
Externí odkaz:
https://doaj.org/article/12bb057f598f476892c196bad6707074
Autor:
Xin Yee Ang, Uma Mageswary Mageswaran, Yi Li Fiona Chung, Boon Kiat Lee, Siti Nur Afiqah Azhar, Nurhanis Syazni Roslan, Ili Farhana Binti Saufian, Nor Sheila Mustaffa, Ermadina Mohamad Kalam, Aini Farhah Ibrahim, Normala Abdul Wahid, Zakuan Zainy Deris, Chern-Ein Oon, Wan Fadhlina Wan Adnan, Salina Sany, Min-Tze Liong
Publikováno v:
Microorganisms, Vol 10, Iss 2, p 285 (2022)
We previously reported on the effects of a lactobacilli probiotic (SynForU-HerCare; two capsules/day of 9.5 log CFU/capsule) in improving symptoms of vaginal irritation, discharge and burning in pregnant women with vaginal candidiasis upon administra
Externí odkaz:
https://doaj.org/article/e3481af70042450ba79d3f7ea9276db7
Autor:
Ashwaq Hamid Salem Yehya, Ayappa V Subramaniam, Muhammad Asif, Gurjeet Kaur, AMS Abdul Majid, Chern Ein Oon
Publikováno v:
World Journal of Gastroenterology. 28:4620-4634
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::07d06236b950960534b701704dc06916
https://doi.org/10.3748/wjg.v28.i32.4620
https://doi.org/10.3748/wjg.v28.i32.4620
Autor:
Yi Jer Tan, Yeuan Ting Lee, Sven H. Petersen, Gurjeet Kaur, Koji Kono, Soo Choon Tan, Amin M. S. Abdul Majid, Chern Ein Oon
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 11 (2019)
Background: This study aims to investigate the combination effect of a novel sirtuin inhibitor (BZD9L1) with 5-fluorouracil (5-FU) and to determine its molecular mechanism of action in colorectal cancer (CRC). Methods: BZD9L1 and 5-FU either as singl
Externí odkaz:
https://doaj.org/article/be58cdc70e6b443cb5da250fd122d14c
Autor:
Chern Ein Oon, Ayappa V Subramaniam, Lik Yang Ooi, Ashwaq Hamid Salem Yehya, Yeuan Ting Lee, Gurjeet Kaur, Sreenivasan Sasidharan, Beiying Qiu, Xiaomeng Wang
Publikováno v:
World journal of gastrointestinal oncology, vol 15, iss 5
BackgroundThe development of new vasculatures (angiogenesis) is indispensable in supplying oxygen and nutrients to fuel tumor growth. Epigenetic dysregulation in the tumor vasculature is critical to colorectal cancer (CRC) progression. Sirtuin (SIRT)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd0e7d694f1f2d8e4fddaad392e63dd2
https://escholarship.org/uc/item/36p774g0
https://escholarship.org/uc/item/36p774g0
Autor:
Adrian L. Harris, Richard Poulsom, Craig P. Montgomery, Angela J. Russell, Partha S. Chowdhury, Herren Wu, Emma T. Bowden, Cameron Snell, Wen Shi, Esther Bridges, Helen Sheldon, Russell Leek, Helen Turley, Chern Ein Oon, Richard C.A. Sainson, Ji-Liang Li
PDF file - 740K, Neither anti-EphrinB2 nor sEphB4 affected the growth of U87-EV tumors in vivo. Compared to the control, neutralizing anti-EphrinB2 antibody (B2) alone (blue arrowhead) did not affect the tumor growth. Also, combined anti-EphrinB2 ant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af3bbe38c8de0da3d76fe6a344de7054
https://doi.org/10.1158/0008-5472.22388565
https://doi.org/10.1158/0008-5472.22388565