Novel neurosteroid pregnanolone pyroglutamate suppresses neurotoxicity syndrome induced by tetramethylenedisulfotetramine but is ineffective in a rodent model of infantile spasms.

Autor: Chern CR; Department of Cell Biology and Anatomy, New York Medical College, Valhalla, NY, USA., Lauková M; Department of Cell Biology and Anatomy, New York Medical College, Valhalla, NY, USA.; Institute of Experimental Endocrinology, Biomedical Research Center of the Slovak Academy of Science, Bratislava, Slovakia., Schonwald A; Department of Cell Biology and Anatomy, New York Medical College, Valhalla, NY, USA., Kudová E; Institute of Organic Chemistry and Biochemistry, Czech Academy of Sciences, Prague, Czech Republic., Chodounská H; Institute of Organic Chemistry and Biochemistry, Czech Academy of Sciences, Prague, Czech Republic., Chern CJ; Department of Cell Biology and Anatomy, New York Medical College, Valhalla, NY, USA., Shakarjian MP; Department of Cell Biology and Anatomy, New York Medical College, Valhalla, NY, USA.; Department of Public Health, Environmental Health Science Program, New York Medical College, Valhalla, NY, USA.; Department of Medicine, Division of Pulmonary and Critical Care Medicine, Rutgers-Robert Wood Johnson Medical School, 675 Hoes Ln W, Piscataway, NJ, 08854, USA., Velíšková J; Department of Cell Biology and Anatomy, New York Medical College, Valhalla, NY, USA.; Department of Obstetrics and Gynecology, New York Medical College, Valhalla, NY, USA.; Department of Neurology, New York Medical College, Valhalla, NY, USA., Velíšek L; Department of Cell Biology and Anatomy, New York Medical College, Valhalla, NY, USA. Libor_Velisek@nymc.edu.; Department of Neurology, New York Medical College, Valhalla, NY, USA. Libor_Velisek@nymc.edu.; Department of Pediatrics, New York Medical College, Valhalla, NY, USA. Libor_Velisek@nymc.edu.

Publikováno v: Pharmacological reports : PR [Pharmacol Rep] 2023 Feb; Vol. 75 (1), pp. 177-188. Date of Electronic Publication: 2022 Nov 23.

AQB-565 shows promise in preclinical testing in the model of epileptic spasms during infancy: Head-to-head comparison with ACTH.

Autor: Chern CR; Department of Cell Biology & Anatomy, New York Medical College School of Medicine, Valhalla, NY, 10595, USA., Chern CJ; Department of Cell Biology & Anatomy, New York Medical College School of Medicine, Valhalla, NY, 10595, USA., Velíšková J; Department of Cell Biology & Anatomy, New York Medical College School of Medicine, Valhalla, NY, 10595, USA; Department of Obstetrics & Gynecology, New York Medical College School of Medicine, Valhalla, NY, 10595, USA; Department of Neurology, New York Medical College School of Medicine, Valhalla, NY, 10595, USA., Velíšek L; Department of Cell Biology & Anatomy, New York Medical College School of Medicine, Valhalla, NY, 10595, USA; Department of Neurology, New York Medical College School of Medicine, Valhalla, NY, 10595, USA; Department of Pediatrics, New York Medical College School of Medicine, Valhalla, NY, 10595, USA. Electronic address: Libor_Velisek@nymc.edu.

Publikováno v: Epilepsy research [Epilepsy Res] 2019 May; Vol. 152, pp. 31-34. Date of Electronic Publication: 2019 Mar 11.

The subunit structure of human muscle and human erythrocyte pyruvate kinase isozymes.

Autor: Peterson JS, Chern CJ, Harkins RN, Black JA

Publikováno v: FEBS letters [FEBS Lett] 1974 Dec 01; Vol. 49 (1), pp. 73-7.

Pyridoxal kinase: decreased activity in red blood cells of Afro-Americans.

Autor: Chern CJ, Beutler E

Publikováno v: Science (New York, N.Y.) [Science] 1975 Mar 21; Vol. 187 (4181), pp. 1084-6.

Localization of the structural locus for cytoplasmic glutamic-oxaloacetic transaminase to region q24 leads to qter of human chromosome 10.

Autor: Chern CJ, Mellman WJ, Croce CM

Publikováno v: Birth defects original article series [Birth Defects Orig Artic Ser] 1976; Vol. 12 (7), pp. 108-10.