Výsledky vyhledávání - "Cheri M. Turman"

An alternatively spliced cytochrome P4501A1 in human brain fails to bioactivate polycyclic aromatic hydrocarbons to DNA-reactive metabolites

Autor: Cheri M. Turman, Henry W. Strobel, Vijayalakshmi Ravindranath, Bhagavatula Moorthy, Lihua Wang, Reddy P. Kommaddi

Publikováno v: Journal of Neurochemistry. 102:867-877

CYP1A1, a cytochrome P450 enzyme, metabolizes polycyclic aromatic hydrocarbons to genotoxic metabolite(s) that bind to DNA and initiate carcinogenesis. RT-PCR amplification of the complete open reading frame of CYP1A1 generated an amplicon of 1593 bp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e9f6011af5e8227563d33815b3918eb0
https://doi.org/10.1111/j.1471-4159.2007.04599.x

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Constitutive expression and localization of cytochrome P‐450 1A1 in rat and human brain: presence of a splice variant form in human brain 1

Autor: Henry W. Strobel, Reddy P. Kommaddi, Shankar J. Chinta, Cheri M. Turman, Vijayalakshmi Ravindranath

Publikováno v: Journal of Neurochemistry. 93:724-736

Cytochrome P-450 function as mono-oxygenases and metabolize xenobiotics. CYP1A1, a cytochrome P-450 enzyme, bioactivates polycyclic aromatic hydrocarbons to reactive metabolite(s) that bind to DNA and initiate carcinogenesis. Northern and immunoblot

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4085c7180e2f20fcbe3800864db3f65b
https://doi.org/10.1111/j.1471-4159.2005.03061.x

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Expression and characterization of human cytochrome P450 4F11: Putative role in the metabolism of therapeutic drugs and eicosanoids

Autor: Yasushi Kikuta, Cheri M. Turman, Auinash Kalsotra, Henry W. Strobel

Publikováno v: Toxicology and Applied Pharmacology. 199:295-304

We previously reported the cDNA cloning of a new CYP4F isoform, CYP4F11. In the present study, we have expressed CYP4F11 in Saccharomyces cerevisiae and examined its catalytic properties towards endogenous eicosanoids as well as some clinically relev

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::064a570b3142ac6114db5e5b9ef5d67b
https://doi.org/10.1016/j.taap.2003.12.033

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CYP4Fs Expression in Rat Brain Correlates with Changes in LTB4 Levels after Traumatic Brain Injury

Autor: Henry W. Strobel, Raymond J. Grill, Cheri M. Turman, Auinash Kalsotra, Jing Zhao, Pramod K. Dash, Ying Wang

Cytochrome P450 (CYP) 4Fs constitute a subgroup of the cytochrome P450 superfamily and are involved in cellular protection and metabolism of numerous molecules, including drugs, toxins, and eicosanoids. CYP4Fs are widely distributed in rat brain with

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::202c4fba2131d958324a0b5659a52f73
https://europepmc.org/articles/PMC2948471/

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Alternative splicing within the human cytochrome P450 superfamily with an emphasis on the brain: The convolution continues

Autor: Vijayalakshmi Ravindranath, Cheri M. Turman, Daniel J. Ryder, Henry W. Strobel, Jade M Hatley

Publikováno v: Expert opinion on drug metabolismtoxicology. 2(3)

The human cytochrome P450 (CYP) superfamily of enzymes regulate hepatic phase 1 drug metabolism and subsequently play a significant role in pharmacokinetics, drug discovery and drug development. Alternative splicing of the cytochrome CYP gene transcr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d453716883f1e0b8adc8079ef6075a7e
https://pubmed.ncbi.nlm.nih.gov/16863442

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Constitutive expression and localization of cytochrome P-450 1A1 in rat and human brain: presence of a splice variant form in human brain

Autor: Shankar J, Chinta, Reddy P, Kommaddi, Cheri M, Turman, Henry W, Strobel, Vijayalakshmi, Ravindranath

Publikováno v: Journal of neurochemistry. 93(3)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::294312f9886cb29a75315bbe893ad9f7
https://pubmed.ncbi.nlm.nih.gov/15836631

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Differential effects of traumatic brain injury on the cytochrome p450 system: a perspective into hepatic and renal drug metabolism

Autor: Henry W. Strobel, Cheri M. Turman, Pramod K. Dash, Auinash Kalsotra

Publikováno v: Journal of neurotrauma. 20(12)

Traumatic brain injury is known to cause several secondary effects, one of which is altered drug clearance. Given the fact that patients who sustain TBI are subsequently treated with a variety of pharmacological agents for the purpose of either neuro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38dd9f0851aa498486de2e975b85d2a5
https://pubmed.ncbi.nlm.nih.gov/14748982

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Note: NAMD–LP: Filtering and Translating NAMD-generated Files

Autor: Eric T. Williams, Cheri M. Turman, Henry W. Strobel

Publikováno v: Molecular Simulation. 31:67-68

Currently, science is in a technological boom with many new and improved scientific tools entering the marketplace. The instruments that have existed for decades have seen improvements in sensitivi...

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7e33a60f0b6fcbff0b76d347f57ac583
https://doi.org/10.1080/08927020512331325774

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Akademický článek

CYP4Fs Expression in Rat Brain Correlates with Changes in LTB4Levels after Traumatic Brain Injury.

Autor: Ying Wang, Jing Zhao, Auinash Kalsotra, Cheri M. Turman, Raymond J. Grill, Pramod K. Dash, Henry W. Strobel

Publikováno v: Journal of Neurotrauma; Oct2008, Vol. 25 Issue 10, p1187-1194, 8p

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Akademický článek

Differential Effects of Traumatic Brain Injury on the Cytochrome P450 System: A Perspective into Hepatic and Renal Drug Metabolism.

Autor: Auinash Kalsotra, Cheri M. Turman, Pramod K. Dash, Henry W. Strobel

Publikováno v: Journal of Neurotrauma; 12/01/2003, Vol. 20 Issue 12, p1339-1350, 12p

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