Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Cheong Yong Yun"'
Autor:
Song-Hee Kim, Jiyeon Lee, Jihye Jung, Ga Hyun Kim, Cheong-Yong Yun, Sang-Hun Jung, Bang Yeon Hwang, Jin Tae Hong, Sang-Bae Han, Jae-Kyung Jung, Youngsoo Kim
Publikováno v:
International Journal of Biological Sciences; 2024, Vol. 20 Issue 5, p1688-1704, 17p
Autor:
Cheong-Yong Yun, Nahyun Choi, Jae Un Lee, Eun Jung Lee, Ji Young Kim, Won Jun Choi, Sang Ho Oh, Jong-Hyuk Sung
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 8, p 3995 (2021)
Nuclear factor erythroid 2-related factor 2 (Nrf2), which is linked to autophagy regulation and melanogenesis regulation, is activated by marliolide. In this study, we investigated the effect of a marliolide derivative on melanosome degradation throu
Externí odkaz:
https://doaj.org/article/d22fe82c866a49f99c6c47bcad2fbb7b
Autor:
Cheong Yong Yun, Youngsoo Kim, Sang-Hun Jung, Da Eun Jung, Eunmiri Roh, Sang-Bae Han, Won-Jea Cho, Jinhe Han, Ga Hyeon Kim, Ji Yeon Lee, Song-Hee Kim
Publikováno v:
Theranostics
Rationale: Microphthalmia-associated transcription factor M (MITF-M) plays important roles in the pigment production, differentiation and survival of melanocytes. Stem cell factor (SCF) and its receptor KIT stimulate MITF-M activity via phosphorylati
Autor:
Eun-Young Shin, Chan-Soo Lee, Cheong-Yong Yun, So-Yoon Won, Hyong-Kyu Kim, Yong Hee Lee, Sahng-June Kwak, Eung-Gook Kim
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e95212 (2014)
Non-muscle myosin II (NM II) regulates a wide range of cellular functions, including neuronal differentiation, which requires precise spatio-temporal activation of Rho GTPases. The molecular mechanism underlying the NM II-mediated activation of Rho G
Externí odkaz:
https://doaj.org/article/91946b084b774f389ca6162e6b4ccbc2
Autor:
Nahyun Choi, Jae Un Lee, Cheong Yong Yun, Won Jun Choi, Eunjung Lee, Ji-Young Kim, Jong Hyuk Sung, Sang Ho Oh
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 8
International Journal of Molecular Sciences, Vol 22, Iss 3995, p 3995 (2021)
Volume 22
Issue 8
International Journal of Molecular Sciences, Vol 22, Iss 3995, p 3995 (2021)
Nuclear factor erythroid 2-related factor 2 (Nrf2), which is linked to autophagy regulation and melanogenesis regulation, is activated by marliolide. In this study, we investigated the effect of a marliolide derivative on melanosome degradation throu
Autor:
Youngsoo Kim, Sang-Hun Jung, Jin Tae Hong, Cheong Yong Yun, Xiang Hua Han, Qinghao Jin, Mi Kyeong Lee, Bang Yeon Hwang, Dongho Lee, Jin Woo Lee, Chul Lee
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 28:1252-1256
Bioassay-guided fractionation of the methanolic extract from the roots of Cynanchum atratum has resulted in the isolation of three new pregnane glycosides (1-3) along with four known compounds (4-7). Their structures were identified by analysis of th
Autor:
Yong Pyo Choi, Bang Yeon Hwang, Jin Yong Song, Ju Yeon Kim, Youngsoo Kim, Jungno Lee, Seon Mi Ko, Cheong-Yong Yun, Song-Hee Kim, Jin Tae Hong, Sang-Bae Han, Beom Joon Kim, Jae Mun Kim
Publikováno v:
Theranostics
Rationale: cAMP up-regulates microphthalmia-associated transcription factor subtype M (MITF-M) and tyrosinase (Tyro) in the generation of heavily pigmented melanosomes. Here, we communicate a therapeutic mechanism of hyperpigmented disorder by α-vin
Autor:
Shinkichi Tawata, Eung-Gook Kim, Cheong-Yong Yun, Hiroshi Maruta, Pham Thi Be Tu, Binh Cao Quan Nguyen
Publikováno v:
Drug Discoveries & Therapeutics. 10:314-322
We previously demonstrated that the oncogenic kinase PAK4, which both melanomas and normal melanocytes express at a very high level, is essential for their melanogenesis. In the present study, using the highly sensitive "Macaroni-Western" (IP-ATP-Glo
Autor:
Cheong Yong Yun, Qinghao Jin, Kwon Ki Bang, Jin Tae Hong, Sang-Hun Jung, Mi Kyeong Lee, Dongho Lee, Bang Yeon Hwang, Jin Woo Lee, Chul Lee, Youngsoo Kim
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 23:3334-3337
Two new daphnane-type diterpene esters, daphneresiniferins A (1) and B (2), along with seven known diterpenes, yuanhuacine (3), yuanhuadine (4), yuanhuahine (5), genkwadaphnin (6), genkwanine A (7), genkwanine F (8), and genkwanine H (9), were isolat
Autor:
Youngsoo Kim, Nam Doo Kim, Dongsun Park, Sang-Hun Jung, Sun Ki Park, Cheong Yong Yun, Eunmiri Roh, Sang-Bae Han, Ji Young Yun, Bang Yeon Hwang, Yun Bae Kim
Publikováno v:
Journal of Investigative Dermatology. 133(4):1072-1079
Microphthalmia-associated transcription factor (MITF) is inducible in response to cAMP and has a pivotal role in the melanocyte-specific expression of tyrosinase for skin pigmentation. Here we suggest that the cAMP-binding site of protein kinase A (P