Zobrazeno 1 - 10
of 240
pro vyhledávání: '"Cheolju, Lee"'
Autor:
Hyondeog Kim, Wonyeop Lee, Youngwook Kim, Sang-Jin Lee, Wonyoung Choi, Geon Kook Lee, Seung-Jin Park, Shinyeong Ju, Seon-Young Kim, Cheolju Lee, Ji-Youn Han
Publikováno v:
Experimental and Molecular Medicine, Vol 56, Iss 9, Pp 2082-2095 (2024)
Abstract Patients with lung adenocarcinoma who have never smoked (NSLA) and lack key driver mutations, such as those in the EGFR and ALK genes, face limited options for targeted therapies. They also tend to have poorer outcomes with immune checkpoint
Externí odkaz:
https://doaj.org/article/2cba0f79170d4894b1ae702c73614477
Autor:
Ji An Kang, Yoon Jung Kim, Kyu Yun Jang, Hye Won Moon, Haeseung Lee, Seonjeong Lee, Hyun Kyu Song, Sang Woo Cho, Yoon Sun Yoo, Hye Gyeong Han, Min-Ju Kim, Myoung Ja Chung, Cheol Yong Choi, Cheolju Lee, Chaeuk Chung, Gang Min Hur, You-Sun Kim, Young Joo Jeon
Publikováno v:
Experimental and Molecular Medicine, Vol 56, Iss 3, Pp 656-673 (2024)
Abstract ISG15 is an interferon-stimulated ubiquitin-like protein (UBL) with multifaceted roles as a posttranslational modifier in ISG15 conjugation (ISGylation). However, the mechanistic consequences of ISGylation in cancer have not been fully eluci
Externí odkaz:
https://doaj.org/article/c826fa42999847ed9a55a5d0b1f2311b
Autor:
Yoon Tae Kim, Jin Won Huh, Yun Hui Choi, Hee Kyeong Yoon, Tram TT Nguyen, Eunho Chun, Geunyeol Jeong, Sunyoung Park, Sungwoo Ahn, Won-Kyu Lee, Young-Woock Noh, Kyoung Sun Lee, Hee-Sung Ahn, Cheolju Lee, Sang Min Lee, Kyung Su Kim, Gil Joon Suh, Kyeongman Jeon, Sunghoon Kim, Mirim Jin
Publikováno v:
EMBO Molecular Medicine, Vol 16, Iss 1, Pp 40-63 (2023)
Abstract Despite intensive clinical and scientific efforts, the mortality rate of sepsis remains high due to the lack of precise biomarkers for patient stratification and therapeutic guidance. Secreted human tryptophanyl-tRNA synthetase 1 (WARS1), an
Externí odkaz:
https://doaj.org/article/95aa08b534b248e8b6128193ae67ae34
Autor:
Yejoo Choi, Sungho Shin, Hyo Jin Son, Na-Hee Lee, Su Hyeon Myeong, Cheolju Lee, Hyemin Jang, Soo Jin Choi, Hee Jin Kim, Duk L. Na
Publikováno v:
Stem Cell Research & Therapy, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Background Preclinical studies showed that mesenchymal stem cells (MSCs) ameliorate tau phosphorylation, amyloid-beta accumulation, and inflammation in Alzheimer’s disease (AD) mouse models via secretion of neurotrophic factors and cytokin
Externí odkaz:
https://doaj.org/article/aa8ddbb3f9aa44e786115a284096bc19
Autor:
Young Jun An, Ye-Eun Jung, Kyeong Won Lee, Prashant Kaushal, In Young Ko, Seung Min Shin, Sangho Ji, Wookyung Yu, Cheolju Lee, Won-Kyu Lee, Kiweon Cha, Jung-Hyun Lee, Sun-Shin Cha, Hyung-Soon Yim
Publikováno v:
PLoS ONE, Vol 19, Iss 9, p e0307499 (2024)
Fibroblast growth factor 2 (FGF2) is an attractive biomaterial for pharmaceuticals and functional cosmetics. To improve the thermo-stability of FGF2, we designed two mutants harboring four-point mutations: FGF2-M1 (D28E/C78L/C96I/S137P) and FGF2-M2 (
Externí odkaz:
https://doaj.org/article/40e83970943d41ca992fa7cd62a2cfcc
Autor:
Kyoung Lae Kim, Hyerim Kim, Youngju Lee, Cheolju Lee, Kwangsic Joo, Sang Jun Park, Kyu Hyung Park, Seong-Jun Park, Se Joon Woo
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-9 (2022)
Abstract The single nucleotide polymorphisms (SNPs) of complement factor H (CFH) gene are well-known genetic risk factors for age-related macular degeneration (AMD). To identify whether the measurement of plasma protein concentrations of CFH variants
Externí odkaz:
https://doaj.org/article/6eca0d860cac4fbba90642f57728b0cb
Autor:
Yoon Tae Kim, Jin Won Huh, Yun Hui Choi, Hee Kyeong Yoon, Tram TT Nguyen, Eunho Chun, Geunyeol Jeong, Sunyoung Park, Sungwoo Ahn, Won-Kyu Lee, Young-Woock Noh, Kyoung Sun Lee, Hee-Sung Ahn, Cheolju Lee, Sang Min Lee, Kyung Su Kim, Gil Joon Suh, Kyeongman Jeon, Sunghoon Kim, Mirim Jin
Publikováno v:
EMBO Molecular Medicine, Vol 16, Iss 3, Pp 665-665 (2024)
Externí odkaz:
https://doaj.org/article/5be677541efd41a2b8e01e7a1f60e14e
Autor:
Hee‐Sung Ahn, Youngju Lee, Hyeong Min Kim, Shinyeong Ju, Seonjeong Lee, Hyeon‐Gyo Jeong, Sang Jun Park, Kyu Hyung Park, Junyeop Lee, Joo Yong Lee, Se Joon Woo, Cheolju Lee
Publikováno v:
Clinical and Translational Medicine, Vol 13, Iss 6, Pp n/a-n/a (2023)
Externí odkaz:
https://doaj.org/article/fbf2a45c427b49beba7e87f08aa38aa9
Autor:
Yumi Kwon, Seong-Jun Park, Binh Thanh Nguyen, Mi Jeong Kim, Sejin Oh, Hwanho Lee, Narae Park, Hyun Seok Kim, Min-Jung Kang, Byung Soh Min, Jin-Won Lee, Eun Gyeong Yang, Cheolju Lee
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-16 (2021)
Abstract The role of matrix metalloproteinase-2 (MMP-2) in tumor cell migration has been widely studied, however, the characteristics and effects of MMP-2 in clinical sample of metastatic colorectal cancer (CRC) remain poorly understood. Here, in ord
Externí odkaz:
https://doaj.org/article/de6e57a07feb41a5899338b437cdc93b
Autor:
Seung Won Choi, Yeri Lee, Kayoung Shin, Harim Koo, Donggeon Kim, Jason K. Sa, Hee Jin Cho, Hye-mi Shin, Se Jeong Lee, Hyunho Kim, Seok Chung, Jihye Shin, Cheolju Lee, Do-Hyun Nam
Publikováno v:
Cell Death and Disease, Vol 12, Iss 4, Pp 1-15 (2021)
Abstract PTEN is one of the most frequently altered tumor suppressor genes in malignant tumors. The dominant-negative effect of PTEN alteration suggests that the aberrant function of PTEN mutation might be more disastrous than deletion, the most freq
Externí odkaz:
https://doaj.org/article/5efec489251247878b469f04eabfdbe7