Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Cheol-Hwan Yoon"'
Autor:
Gi-Su Oh, Wa Cao, Cheol-Hwan Yoon, Dipendra Khadka, Tae Hwan Kwak, Mengyu Zhu, Byung-Ouk Park, Hong-Seob So, Hyeok Shim, Su-Bin Lee, SeungHoon Lee, Hyungjin Kim
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 12085, p 12085 (2021)
Volume 22
Issue 21
International Journal of Molecular Sciences, Vol 22, Iss 12085, p 12085 (2021)
Volume 22
Issue 21
Cancer-associated thrombosis is the second-leading cause of mortality in patients with cancer and presents a poor prognosis, with a lack of effective treatment strategies. NAD(P)H quinone oxidoreductase 1 (NQO1) increases the cellular nicotinamide ad
Publikováno v:
Transactions of the Korean Society of Mechanical Engineers - A. 42:363-369
Autor:
Masako Kuno, Huang Shih-Chung, Gil Nam Lee, Syunsuke Yamamoto, Suk Young Cho, Kazuyoshi Aso, Masato Yoshida, Shogo Marui, Norihito Tokunaga, Yusuke Ohba, Takatoshi Yogo, Hideyuki Nakagawa, Satoshi Sasaki, Masaki Seto, Atsutoshi Okabe, Takahiro Miyazaki, Chul Yun Rhim, Yousuke Satou, Robert J. Skene, Cheol Hwan Yoon, Hiroyuki Nagamiya
Publikováno v:
Journal of medicinal chemistry. 59(2)
We report herein the discovery and optimization of 3-amino-1,5-dihydro-4H-pyrazolopyridin-4-one TYK2 inhibitors. High-throughput screening against TYK2 and JAK1-3 provided aminoindazole derivative 1 as a hit compound. Scaffold hopping of the aminoind
Publikováno v:
Journal of Construction Engineering and Project Management. 1:11-17
Recent demands from construction industry have emphasized the capability for graduates to have improved skills both technical and non-technical such as problem solving, interpersonal communication. To satisfy these demands, problem-based learning tha
Publikováno v:
Journal of the American Chemical Society. 128:16384-16393
We report herein the development of a general and mild protocol of oxygen-promoted Pd(II) catalysis resulting in the selective cross-couplings of alkenyl- and arylboron compounds with various olefins. Unlike most cross-coupling reactions, this new me
Publikováno v:
Tetrahedron Letters. 46:143-146
Highly functionalized chiral γ-lactams are efficiently synthesized via Rh(II) catalyzed intramolecular C–H insertion from various α-diazoamides. Independent of α-substituents, regio- and stereoselectivities are enhanced through a conformational
Autor:
Kyung Woon Jung, Ralph N. Salvatore, Richard M. Cross, Advait S. Nagle, Suma Sahab, Elona A. Kapxhiu, Cheol Hwan Yoon
Publikováno v:
Tetrahedron Letters. 44:5695-5698
Efficient synthetic methods were developed for the synthesis of mono xanthates, as well as mono dithiocarbamates of diamines and amino alcohols. This protocol utilizes the three component coupling of diols, diamines, and amino alcohols using alkyl br
Autor:
David J. Merkler, Derek D Poore, Geoffrey H. Chew, Lamar Galloway, Kathleen A. Merkler, Cheol Hwan Yoon, Mitchell Anthony Delong, Advait S. Nagle, Kyung Woon Jung, Laura Aaron Miller, Laura E. Baumgart
Publikováno v:
Archives of Biochemistry and Biophysics. 412:3-12
The C-terminal α-amide moiety of most peptide hormones arises by the posttranslational cleavage of a glycine-extended precursor in a reaction catalyzed by bifunctional peptidylglycine α-amidating monooxygenase (PAM). Glutathione and the S -alkylate
Publikováno v:
Tetrahedron. 57:7785-7811
Autor:
Kyung Woon Jung, Kyung Soo Yoo, Cheol Hwan Yoon, Justin O'Neill, Satoshi Sakaguchi, Chan Pil Park
Publikováno v:
Organic Letters. 9:3933-3935
Herein, we report an asymmetric intermolecular Heck-type reaction of acyclic alkenes by using a palladium-pyridinyl oxazoline diacetate complex under oxidative palladium(II) catalysis conditions. A premade palladium-ligand complex afforded higher ena