Zobrazeno 1 - 10
of 155
pro vyhledávání: '"Cheol Hyeon Kim"'
Autor:
Seo Yun Kim, M.D., Jae Kyung Myung, M.D., Hye-Ryoun Kim, M.D., Im Il Na, M.D., Ph.D., Jae Soo Koh, M.D., Ph.D., Hee Jong Baek, M.D., Ph.D., Cheol Hyeon Kim, M.D., Ph.D.
Publikováno v:
Tuberculosis and Respiratory Diseases, Vol 82, Iss 1, Pp 62-70 (2019)
Background Epidermal growth factor receptor (EGFR) mutations in non-small cell lung cancers have emerged as key predictive biomarkers in EGFR tyrosine kinase inhibitor (TKI) treatment. However, a few patients with wild-type EGFR also respond to EGFR
Externí odkaz:
https://doaj.org/article/1c41828b866545c4b7f3fb575c38a2a0
Autor:
Seo Yun Kim, Hye-Ryoun Kim, Cheol Hyeon Kim, Jae Soo Koh, Hee Jong Baek, Chang-Min Choi, Joon Seon Song, Jae Cheol Lee, Im Il Na
Publikováno v:
Annals of Thoracic Medicine, Vol 12, Iss 1, Pp 36-41 (2017)
BACKGROUND: The aim of this study was to investigate the association between epidermal growth factor receptor (EGFR) mutation and thyroid cancer in female patients with nonsmall-cell lung cancer (NSCLC). METHODS: In a retrospective study, we examine
Externí odkaz:
https://doaj.org/article/4dbca0b5082445f0b85f5e5cf1260ece
Autor:
Kwang Sup So, Cheol Hyeon Kim, Jin Kyung Rho, Sun Ye Kim, Yun Jung Choi, Joon Seon Song, Woo Sung Kim, Chang Min Choi, Young Jin Chun, Jae Cheol Lee
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e114000 (2014)
Protein kinase CK2 has diverse functions promoting and maintaining cancer phenotypes. We investigated the effect of CK2 inhibition in lung cancer cells with T790M-mediated resistance to the EGFR-TK inhibitor. Resistant sublines of PC-9 to gefitinib (
Externí odkaz:
https://doaj.org/article/398038b4215545b6a64ea5301f546661
Autor:
Jae Cheol Lee, Young Do Yoo, Cheol Hyeon Kim, Seung Sook Lee, Sung Hyun Yang, Im Il Na, Baek-Yeol Ryoo, Jin Kyung Lee, Yun Jung Choi, Jin Kyung Rho
Supplementary Data from The Role of MET Activation in Determining the Sensitivity to Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c1bfe6cb8a238e3714cd2bd90b16b9e
https://doi.org/10.1158/1541-7786.22521657
https://doi.org/10.1158/1541-7786.22521657
Autor:
Jae Cheol Lee, Young Do Yoo, Cheol Hyeon Kim, Seung Sook Lee, Sung Hyun Yang, Im Il Na, Baek-Yeol Ryoo, Jin Kyung Lee, Yun Jung Choi, Jin Kyung Rho
The development of resistance to epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKI) seems almost inevitable, even in patients with lung cancer that initially respond well to EGFR-TKIs. MET amplification was recently found to be a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10b33092749f4c6458d9400aac523bcb
https://doi.org/10.1158/1541-7786.c.6543099.v1
https://doi.org/10.1158/1541-7786.c.6543099.v1
Autor:
Jae Cheol Lee, Trever G. Bivona, Cheol Hyeon Kim, Joon Seon Song, Woo Sung Kim, Jeong Kon Kim, Young Hoon Sung, Chang Hoon Ha, Joo-Yong Lee, In-Jeoung Baek, Dong-Cheol Woo, Sang-Yeob Kim, Dong Sik Jung, Jaesang Lee, Jungmi Lee, Paresh Salgaonkar, Ho-Juhn Song, Byung-Chul Suh, Jaekyoo Lee, Jong Sung Koh, Jae-Young Hur, Chang-Min Choi, Yun Jung Choi, In Yong Lee, Jin Kyung Rho
This file contains Supplemental figures, tables, and legends that accompany the main figures, as indicated in each legend. There are 3 supplemental tables and 6 supplemental figures. Table S1. List of potential target of the GNS compounds that were p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28fbfdb0cad0f1772b6b368fa9c4115c
https://doi.org/10.1158/0008-5472.22416605.v1
https://doi.org/10.1158/0008-5472.22416605.v1
Autor:
Jae Cheol Lee, Trever G. Bivona, Cheol Hyeon Kim, Joon Seon Song, Woo Sung Kim, Jeong Kon Kim, Young Hoon Sung, Chang Hoon Ha, Joo-Yong Lee, In-Jeoung Baek, Dong-Cheol Woo, Sang-Yeob Kim, Dong Sik Jung, Jaesang Lee, Jungmi Lee, Paresh Salgaonkar, Ho-Juhn Song, Byung-Chul Suh, Jaekyoo Lee, Jong Sung Koh, Jae-Young Hur, Chang-Min Choi, Yun Jung Choi, In Yong Lee, Jin Kyung Rho
The clinical utility of approved EGFR small-molecule kinase inhibitors is plagued both by toxicity against wild-type EGFR and by metastatic progression in the central nervous system, a disease sanctuary site. Here, we report the discovery and preclin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f7cd0dfbfd4a73ff7f0193f395524f27
https://doi.org/10.1158/0008-5472.c.6509597.v1
https://doi.org/10.1158/0008-5472.c.6509597.v1
Autor:
Jae Cheol Lee, Cheol Hyeon Kim, Sung Hyun Yang, Im II Na, Baek-Yeol Ryoo, Yun Jung Choi, Jin Kyung Rho
Supplementary Figure 1 from p53 Enhances Gefitinib-Induced Growth Inhibition and Apoptosis by Regulation of Fas in Non–Small Cell Lung Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::105a120949fe98840336af66f3a8b6f1
https://doi.org/10.1158/0008-5472.22366488.v1
https://doi.org/10.1158/0008-5472.22366488.v1
Autor:
Jae Cheol Lee, Cheol Hyeon Kim, Sung Hyun Yang, Im II Na, Baek-Yeol Ryoo, Yun Jung Choi, Jin Kyung Rho
Treatment with gefitinib, a specific inhibitor of epidermal growth factor receptor tyrosine kinase (EGFR-TK), has resulted in dramatic responses in some patients with non–small cell lung cancer (NSCLC). Most patients who respond to gefitinib have E
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb8cfe01f0293698735a2c41f611e5c7
https://doi.org/10.1158/0008-5472.c.6495159.v1
https://doi.org/10.1158/0008-5472.c.6495159.v1
Autor:
Seo Yun Kim, Hyo-Rak Lee, Cheol Hyeon Kim, Hye Jin Kang, Hyesil Seol, Yoon Jung Jang, Sung Hyun Yang, Hong Kyu Jung, Hye-Ryoun Kim, Im Il Na
Publikováno v:
Translational Cancer Research
Background The incidence of second primary lung cancer (SPLC) is increasing with longer survival rates from breast cancer. Despite of studies to suggest the mutual exclusivity of epidermal growth factor receptor (EGFR) and human epidermal growth rece