Zobrazeno 1 - 10
of 72
pro vyhledávání: '"Cheol Hwangbo"'
Autor:
Ki-Jun Ryu, Ki Won Lee, Seung-Ho Park, Taeyoung Kim, Keun-Seok Hong, Hyemin Kim, Minju Kim, Dong Woo Ok, Gu Neut Bom Kwon, Young-Jun Park, Hyuk-Kwon Kwon, Cheol Hwangbo, Kwang Dong Kim, J. Eugene Lee, Jiyun Yoo
Publikováno v:
Molecular Cancer, Vol 23, Iss 1, Pp 1-20 (2024)
Abstract Breast cancer remains a significant health concern, with triple-negative breast cancer (TNBC) being an aggressive subtype with poor prognosis. Epithelial-mesenchymal transition (EMT) is important in early-stage tumor to invasive malignancy p
Externí odkaz:
https://doaj.org/article/457cffecd28f49edbc1da6ec9283cbc9
Autor:
Bo-Gyeong Seo, In-Won Lee, Hyo-Jin Kim, Yeon-Ji Lee, Okhwa Kim, Joon-Hee Lee, Jeong-Hyung Lee, Cheol Hwangbo
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Endothelial cell dysfunction can lead to various vascular diseases. Blood flow disorder is a common symptom of vascular diseases. Regenerative angiogenesis, which involves transplanting vascular cells or stem cells into the body to shape new
Externí odkaz:
https://doaj.org/article/cebc7c746ad6402f845fc98d860b0792
Publikováno v:
Immunity & Ageing, Vol 20, Iss 1, Pp 1-11 (2023)
Abstract TLR4, a transmembrane receptor, plays a central role in the innate immune response. TLR4 not only engages with exogenous ligands at the cellular membrane’s surface but also interacts with intracellular ligands, initiating intricate intrace
Externí odkaz:
https://doaj.org/article/7f318e570edd460dbc1c411fd9971cbb
Autor:
In-Won Lee, Hyeon-Geun Lee, Dae-Ky Moon, Yeon-Ji Lee, Bo-Gyeong Seo, Sang-Ki Baek, Tae-Suk Kim, Cheol Hwangbo, Joon-Hee Lee
Publikováno v:
Journal of Animal Reproduction and Biotechnology, Vol 38, Iss 3, Pp 109-120 (2023)
Background: Pluripotent stem cells (PSCs) including embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs) offer the immense therapeutic potential in stem cell-based therapy of degenerative disorders. However, clinical trials of human
Externí odkaz:
https://doaj.org/article/f35587af051c4201b7b6cf68a681d51b
Publikováno v:
Current Issues in Molecular Biology, Vol 44, Iss 12, Pp 5848-5865 (2022)
Triple-negative breast cancer (TNBC) is more difficult to treat and has a higher mortality rate than other subtypes. Although hormone receptor-targeted therapy is an effective treatment to increase survival rate in breast cancer patients, it is not s
Externí odkaz:
https://doaj.org/article/8ab705f5ddea4c4e9a1aa354ca26b555
Autor:
Ki Won Lee, Dang Thi Nguyen, Minju Kim, Si Hyeon Lee, Seyeon Lim, Jisu Kim, Ki Hun Park, Jeong Yoon Kim, Jiyun Yoo, Cheol Hwangbo, Kwang Dong Kim
Publikováno v:
Current Issues in Molecular Biology, Vol 44, Iss 7, Pp 2856-2867 (2022)
In this study, we investigated the depigmentation effect of Amorpha fruticosa L. root extract (RE), an herbal medicine. A. fruticosa RE significantly induced depigmentation in α-MSH-treated B16F10 cells at noncytotoxic concentrations. Further, the R
Externí odkaz:
https://doaj.org/article/0aa26d678acb449492db2f0cdab88107
Publikováno v:
Cell Death and Disease, Vol 13, Iss 2, Pp 1-15 (2022)
Abstract Small extracellular vesicles (sEVs) play a pivotal role in tumor progression by mediating intercellular communication in the tumor microenvironment (TME). Syntenin-1 induces malignant tumor progression in various types of human cancers, incl
Externí odkaz:
https://doaj.org/article/3910e736636d4a45bead2215b37e71af
Autor:
JaeKyoung Ahn, Hankyeol Jeong, Bo-Gyeong Seo, Ki-Soo Park, Cheol Hwangbo, Han-Gyul Kim, Jin-Sin Koh, Jaemin Kim
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
Vascular aging plays a pivotal role in the morbidity and mortality of older people. Reactive hyperemia index (RHI) detected by pulse amplitude tonometry (PAT) is a non-invasive measure of vascular endothelial function and aging-induced pathogenesis o
Externí odkaz:
https://doaj.org/article/995f315dec394ae4a5070fc3af31b5ba
Publikováno v:
Oncogenesis, Vol 10, Iss 2, Pp 1-14 (2021)
Abstract Transforming growth factor-β (TGF-β) signaling pathways are well-recognized for their role in proliferation and epithelial–mesenchymal transition (EMT) of cancer cells, but much less is understood about their contribution to interactions
Externí odkaz:
https://doaj.org/article/a11cde207c6c417d8068efd56b3f833e
Autor:
Sun‐Mi Park, Seung‐Ho Park, Ki‐Jun Ryu, In‐Kyu Kim, Hyeontak Han, Hyo‐Jin Kim, Seon‐Hee Kim, Keun‐Seok Hong, Hyemin Kim, Minju Kim, Bok Im Cho, Jeong Doo Heo, Na Hyun Kim, Eun Mi Hwang, Jae‐Yong Park, Jong In Yook, Hee Jun Cho, Cheol Hwangbo, Kwang Dong Kim, Hoseok Song, Jiyun Yoo
Publikováno v:
Molecular Oncology, Vol 13, Iss 5, Pp 1280-1295 (2019)
The epithelial–mesenchymal transition (EMT) plays a pivotal role in the conversion of early‐stage tumors into invasive malignancies. The transcription factor Snail, an extremely unstable protein whose subcellular levels are regulated by many E3 u
Externí odkaz:
https://doaj.org/article/bd07f8dabbbc4312923f28bc0aa8f877