Zobrazeno 1 - 10
of 114
pro vyhledávání: '"Cheok Soon Lee"'
Autor:
Seul A Lee, Fang Liu, Doo Young Yun, Stephen M Riordan, Alfred Chin Yen Tay, Lu Liu, Cheok Soon Lee, Li Zhang
Publikováno v:
Journal of Oral Microbiology, Vol 13, Iss 1 (2021)
Introduction: Campylobacter concisus is an oral bacterium that is associated with inflammatory bowel disease (IBD) and Barrett’s esophagus (BE). Programmed cell death ligand-1 (PD-L1) is an immune checkpoint protein that is used by tumor cells for
Externí odkaz:
https://doaj.org/article/743591f5507e421fa99aadc2346811c8
Autor:
Vincent Ho, Liping Chung, Amandeep Singh, Vivienne Lea, Askar Abubakar, Stephanie H. Lim, Weng Ng, Mark Lee, Paul de Souza, Joo-Shik Shin, Cheok Soon Lee
Publikováno v:
BMC Cancer, Vol 18, Iss 1, Pp 1-11 (2018)
Abstract Background The MRE11/RAD50/NBS1 (MRN) complex plays an essential role in detecting and repairing double-stranded breaks, and thus the potential roles of MRE11, RAD50 and NBS1 proteins in the pathogenesis of various cancers is the subject of
Externí odkaz:
https://doaj.org/article/5e214742cec648bfa017871cf3777701
Autor:
Kenneth Lai, Slade Matthews, James S. Wilmott, Murray C. Killingsworth, Jim L. Yong, Nicole J. Caixeiro, James Wykes, Allan Samakeh, Dion Forstner, Mark Lee, John McGuinness, Navin Niles, Angela Hong, Ardalan Ebrahimi, Cheok Soon Lee
Publikováno v:
BMC Cancer, Vol 18, Iss 1, Pp 1-12 (2018)
Abstract Background This study examined the prognostic significance of microtubule-associated protein light chain 3B (LC3B) expression in oropharyngeal and oral cavity squamous cell carcinoma (SCC). The prognostic significance of LC3B expression in r
Externí odkaz:
https://doaj.org/article/c40ec2a3a86d4c33af24aeb48994583b
Autor:
Nicholas Nikesitch, Patricia Rebeiro, Lye Lin Ho, Srinivasa Pothula, Xin Maggie Wang, Tiffany Khong, Hazel Quek, Andrew Spencer, Cheok Soon Lee, Tara L. Roberts, Silvia C. W. Ling
Publikováno v:
Cells, Vol 10, Iss 12, p 3464 (2021)
Background: Multiple myeloma (MM) remains incurable despite high-dose chemotherapy, autologous stem cell transplants and novel agents. Even with the improved survival of MM patients treated with novel agents, including bortezomib (Bz), the therapeuti
Externí odkaz:
https://doaj.org/article/bd3fc280fd42417892d6a0aacc02231d
Publikováno v:
PLoS ONE, Vol 14, Iss 4, p e0214604 (2019)
Breast cancer is a heterogeneous disease displaying different histopathological characteristics, molecular profiling and clinical behavior. This study describes the expression patterns of senescence markers P53, DEC1 and DCR2 and assesses their signi
Externí odkaz:
https://doaj.org/article/d4cfacb21fc04914b3f2b4beabf79106
Publikováno v:
Cells, Vol 10, Iss 5, p 1082 (2021)
Thyroid cancer is the most prevalent endocrine malignancy that comprises mostly indolent differentiated cancers (DTCs) and less frequently aggressive poorly differentiated (PDTC) or anaplastic cancers (ATCs) with high mortality. Utilisation of next-g
Externí odkaz:
https://doaj.org/article/d8b8b97947614614ae0bd9392be23fe3
Autor:
Robert Yoon, Kate Wilkinson, Gabriel Gabriel, Nasreen Kadaan, Tara Roberts, Stephanie Lim, Ray Asghari, Cheok Soon Lee, Wei Chua, Weng Ng
Publikováno v:
Asia-Pacific Journal of Clinical Oncology.
Autor:
Cheok Soon Lee, Tara L. Roberts, Stephanie H Lim, Wei Chua, Weng Ng, Kate Wilkinson, Therese M. Becker
Publikováno v:
Journal of Clinical Pathology
The role of the local tumour and stromal immune landscape is increasingly recognised to be important in cancer development, progression and response to therapy. The composition, function, spatial orientation and gene expression profile of the infiltr
Publikováno v:
Journal of Clinical Pathology. 74:759-765
In 1989, Stephen Paget proposed the ‘seed and soil’ theory of cancer metastasis. This theory has led to previous researchers focusing on the role of a tumour as a cancer seed and antiangiogenesis agents as cancer soil fumigant; for the latter to
Autor:
Hui-Chi Lai, Cheok Soon Lee, Yi Chieh Lim, Uda Ho, Simon H. Apte, John Luff, Martin F. Lavin, Hazel Quek, Alexander James, Tara L. Roberts
Publikováno v:
Journal of Cellular and Molecular Medicine
Suppressor of morphogenesis in genitalia 1 (SMG1) and ataxia telangiectasia mutated (ATM) are members of the PI3‐kinase like–kinase (PIKK) family of proteins. ATM is a well‐established tumour suppressor. Loss of one or both alleles of ATM resul