Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Chenzhong Xu"'
Autor:
Doudou Liu, Chenzhong Xu, Ze Gong, Yijie Zhao, Zhiqiang Fang, Xiaoli Rao, Qingyu Chen, Guodong Li, Wei Kong, Jun Chen
Publikováno v:
Cell Death and Disease, Vol 14, Iss 11, Pp 1-14 (2023)
Abstract Age-associated hypercoagulability is accompanied by the increase of plasma levels of some coagulation factors including fibrinogen which may contribute to the increased risk of cardiovascular, cerebrovascular, and thrombotic diseases in elde
Externí odkaz:
https://doaj.org/article/ffaa920b03714b408c4ec66373e3bf0f
Autor:
Ben Wang, Jin Zhang, Guo Li, Chenzhong Xu, Langmei Yang, Jie Zhang, Yalan Wu, Ye Liu, Zuojun Liu, Ming Wang, Ji Li, Xiaolong Tang, Baohua Liu
Publikováno v:
Cell Death Discovery, Vol 9, Iss 1, Pp 1-10 (2023)
Abstract Cutaneous wound healing, an integral part for protection of skin barrier, is a complex biological process and intimately associated with keratinocyte migration. However, mechanisms regulating keratinocyte migration in the process of cutaneou
Externí odkaz:
https://doaj.org/article/74254dd66ecb4fa9a4a752780c1e0284
Autor:
Jie Sun, Ming Wang, Yaqi Zhong, Xuan Ma, Shimin Sun, Chenzhong Xu, Linyuan Peng, Guo Li, Liting Zhang, Zuojun Liu, Ding Ai, Baohua Liu
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
Monitoring the aging process in vivo is challenging. Here the authors generate a Glb1 +/m‒Glb1-2A-mCherry (GAC) reporter mouse model, where the GAC signal is consistently correlated with established biomarkers of cellular senescence, cardiac hypert
Externí odkaz:
https://doaj.org/article/790afbfd48bd4a7b9522812603435f76
Autor:
Yuanyuan Su, Zhaomeng Sun, Jun Chen, Yanxue Xue, Li Su, Yao Liang, Tanjun Tong, Lijun Zhao, Guodong Li, Qing Fang, Chenzhong Xu
Publikováno v:
Aging (Albany NY)
The activation of transcription factor NF-κB is currently identified as one of the driving forces to the aging process. Genetic impairment of NF-κB signaling pathway or pharmacological inhibition of NF-κB activity has been shown to extend healthsp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43602857a37f20b9b7be1c260e0c6165
http://europepmc.org/articles/PMC6535057
http://europepmc.org/articles/PMC6535057
Publikováno v:
Aging (Albany NY)
Senescent cells display the senescence-associated secretory phenotype (SASP) which plays important roles in cancer, aging, etc. Cell surface-bound IL-1α is a crucial SASP factor and acts as an upstream regulator to induce NF-κB activity and subsequ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3692e29aea7b89b9aa06762d9853395d
http://europepmc.org/articles/PMC6366962
http://europepmc.org/articles/PMC6366962
Autor:
Jie Sun, Ming Wang, Yaqi Zhong, Xuan Ma, Shimin Sun, Chenzhong Xu, Linyuan Peng, Guo Li, Liting Zhang, Zuojun Liu, Ding Ai, Baohua Liu
Publikováno v:
Nature communications. 13(1)
The progressive decline of physiological function and the increased risk of age-related diseases challenge healthy aging. Multiple anti-aging manipulations, such as senolytics, have proven beneficial for health; however, the biomarkers that label in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::098927390cd1de21a55d861d768d24e7
https://pubmed.ncbi.nlm.nih.gov/36396643
https://pubmed.ncbi.nlm.nih.gov/36396643
Autor:
Tanjun Tong, Yuanyuan Su, Na Zhang, Doudou Liu, Guodong Li, Chenzhong Xu, Yao Liang, Jun Chen
Publikováno v:
Cell Death Discovery
Cell Death Discovery, Vol 6, Iss 1, Pp 1-14 (2020)
Cell Death Discovery, Vol 6, Iss 1, Pp 1-14 (2020)
The histone acetyltransferase (HAT) KAT7/HBO1/MYST2 plays a crucial role in the pre-replication complex (pre-RC) formation, DNA replication and cell proliferation via acetylation of histone H4 and H3. In a search for protein kinase D1 (PKD1)-interact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::356b30f2dd399d80787350cf5263493e
http://europepmc.org/articles/PMC7501302
http://europepmc.org/articles/PMC7501302
Autor:
Yao Liang, Tanjun Tong, Na Zhang, Guodong Li, Jun Chen, Doudou Liu, Yuanyuan Su, Chenzhong Xu
The Polycomb group (PcG) protein chromobox 8 (CBX8) is the subunit of Polycomb repressive complex 1 (PRC1) and recognizes the trimethylation of histone H3 on Lysine 27 (H3K27me3), and coordinates with PRC2 complex to function as epigenetic gene silen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a81d1b7d6423bff8e432ecc598ef46ae
https://doi.org/10.1101/2020.08.09.242891
https://doi.org/10.1101/2020.08.09.242891
Publikováno v:
IEEE Transactions on Parallel and Distributed Systems. 28:1853-1865
Multi-tiered Parallel I/O systems that combine traditional HDDs with emerging SSDs mitigate the cost burden of SSDs while benefiting from their superior I/O performance. While a multi-tiered parallel I/O system is promising for data-intensive applica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fb88c47a69352026b2cfa6ea1ae51aeb
https://doi.org/10.1109/tpds.2016.2636837
https://doi.org/10.1109/tpds.2016.2636837