Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Chenyuan Huang"'
Autor:
Yub Raj Neupane, Harish K. Handral, Syed Abdullah Alkaff, Wei Heng Chng, Gopalakrishnan Venkatesan, Chenyuan Huang, Choon Keong Lee, Jiong-Wei Wang, Gopu Sriram, Rhonnie Austria Dienzo, Wen Feng Lu, Yusuf Ali, Bertrand Czarny, Giorgia Pastorin
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 13, Iss 5, Pp 1887-1902 (2023)
Wound healing is a dynamic process that involves a series of molecular and cellular events aimed at replacing devitalized and missing cellular components and/or tissue layers. Recently, extracellular vesicles (EVs), naturally cell-secreted lipid memb
Externí odkaz:
https://doaj.org/article/92a2faa84c1b426da52c611cd124235b
Autor:
Steven Santino Leonardi, Eileen Yiling Koh, Lei Deng, Chenyuan Huang, Lingjun Tong, Jiong-Wei Wang, Kevin Shyong-Wei Tan
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
Blastocystis is a genus of single-celled protist belonging to the stramenopile group. Prior studies have shown that isolates of Blastocystis subtype 7 (ST7) induced higher levels of intestinal epithelial cell damage and gut microbiota dysbiosis in co
Externí odkaz:
https://doaj.org/article/9dc5a1a478314f10ae51385b8a2ae64d
Autor:
Wei Heng Chng, Ram Pravin Kumar Muthuramalingam, Charles Kang Liang Lou, Silas New, Yub Raj Neupane, Choon Keong Lee, Ayca Altay Benetti, Chenyuan Huang, Praveen Thoniyot, Wei Seong Toh, Jiong-Wei Wang, Giorgia Pastorin
Publikováno v:
Pharmaceutics, Vol 15, Iss 4, p 1290 (2023)
Extracellular vesicles (EVs), which are miniaturised carriers loaded with functional proteins, lipids, and nucleic acid material, are naturally secreted by cells and show intrinsic pharmacological effects in several conditions. As such, they have the
Externí odkaz:
https://doaj.org/article/3509817863cd45cd83d440f441bbcbd1
Autor:
Xiong Chang Lim, Chenyuan Huang, Siti Maryam J. M. Yatim, Suet Yen Chong, Sock Hwee Tan, Xiaoxun Yang, Caryn L. Heldt, Jodi Pedersen, Michael Talanker, Harshvardhan Modh, Matthias G. Wacker, Giorgia Pastorin, Siew Pang Chan, A. Mark Richards, Chris J. Charles, Mark Y. Chan, Jiong-Wei Wang
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 1, p 327 (2022)
The subset of plasma extracellular vesicles (EVs) that coprecipitate with low-density lipoprotein (LDL-EVs) carry coagulation and fibrinolysis pathway proteins as cargo. We investigated the association between LDL-EV hemostatic/fibrinolysis protein r
Externí odkaz:
https://doaj.org/article/e93df8154a1f4cad86dd61a238ce629b
Autor:
Yi-Hsuan Ou, Jeremy Liang, Wei Heng Chng, Ram Pravin Kumar Muthuramalingam, Zi Xiu Ng, Choon Keong Lee, Yub Raj Neupane, Jia Ning Nicolette Yau, Sitong Zhang, Charles Kang Liang Lou, Chenyuan Huang, Jiong-Wei Wang, Giorgia Pastorin
Publikováno v:
Pharmaceutics, Vol 14, Iss 8, p 1738 (2022)
In drug delivery, the development of nanovesicles that combine both synthetic and cellular components provides added biocompatibility and targeting specificity in comparison to conventional synthetic carriers such as liposomes. Produced through the f
Externí odkaz:
https://doaj.org/article/5e247a90d3ae43d392aa189c3d0235bb
Autor:
Elise L. Kessler, Jiong-Wei Wang, Bart Kok, Maike A. Brans, Angelique Nederlof, Leonie van Stuijvenberg, Chenyuan Huang, Aryan Vink, Fatih Arslan, Igor R. Efimov, Carolyn S. P. Lam, Marc A. Vos, Dominique P. V. de Kleijn, Magda S. C. Fontes, Toon A. B. van Veen
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 21, p 11823 (2021)
Involvement of the Toll-like receptor 4 (TLR4) in maladaptive cardiac remodeling and heart failure (HF) upon pressure overload has been studied extensively, but less is known about the role of TLR2. Interplay and redundancy of TLR4 with TLR2 have bee
Externí odkaz:
https://doaj.org/article/ba8d61b686094645bdc5db31469aedd9
Autor:
Yub Raj Neupane, Chenyuan Huang, Xiaoyuan Wang, Wei Heng Chng, Gopalakrishnan Venkatesan, Olga Zharkova, Matthias Gerhard Wacker, Bertrand Czarny, Gerrit Storm, Jiong-Wei Wang, Giorgia Pastorin
Publikováno v:
Pharmaceutics, Vol 13, Iss 7, p 1052 (2021)
Recently, bioinspired cell-derived nanovesicles (CDNs) have gained much interest in the field of nanomedicine due to the preservation of biomolecular structure characteristics derived from their parent cells, which impart CDNs with unique properties
Externí odkaz:
https://doaj.org/article/5e19a1463492410290d1b7727ef5226d
Autor:
Suet Yen Chong, Choon Keong Lee, Chenyuan Huang, Yi Hsuan Ou, Christopher J. Charles, Arthur Mark Richards, Yub Raj Neupane, Maria Vazquez Pavon, Olga Zharkova, Giorgia Pastorin, Jiong-Wei Wang
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 13, p 3272 (2019)
Cardiovascular diseases (CVD) represent the leading cause of morbidity and mortality globally. The emerging role of extracellular vesicles (EVs) in intercellular communication has stimulated renewed interest in exploring the potential application of
Externí odkaz:
https://doaj.org/article/93eb72fa88494a8eb20edb9dedfcb4dc
Autor:
Lingjun Tong, Sitong Zhang, Qiqi Liu, Chenyuan Huang, Haining Hao, Michelle Siying Tan, Xiaodong Yu, Charles Kang Liang Lou, Rong Huang, Zhe Zhang, Tongjie Liu, Pimin Gong, Cheng Han Ng, Mark Muthiah, Giorgia Pastorin, Matthias Gerhard Wacker, Xiaoyuan Chen, Gert Storm, Cheun Neng Lee, Lanwei Zhang, Huaxi Yi, Jiong-Wei Wang
Publikováno v:
Science Advances. 9
Milk-derived extracellular vesicles (mEVs) have been proposed as a potential nanomedicine for intestinal disorders; however, their impact on intestinal barrier integrity in gut inflammation and associated metabolic diseases has not been explored yet.
Autor:
Paul L. Bigliardi, Chenyuan Huang, Yuri Dancik, Aneesh V. Karkhanis, Gopalakrishnan Venkatesan, Giorgia Pastorin, Yub Raj Neupane, Zhi Chiaw Lim
Publikováno v:
Archives of Toxicology. 96:153-165
Para-phenylenediamine (PPD) is one of the most used chemicals in oxidative hair dyes. However, its use has been associated with adverse effects on health, including contact dermatitis and other systemic toxicities. Novel PPD derivatives have been pro