Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Chenxu, Ge"'
Autor:
Qiang Li, Yanbin Zheng, Jianyu Zhao, Xinyi Wei, Zongxin Shi, Haonan Fan, Chenxu Ge, Minxuan Xu, Jun Tan
Publikováno v:
Journal of Functional Foods, Vol 122, Iss , Pp 106470- (2024)
Diabetic kidney disease (DKD) is a major diabetic complication and a leading cause of end-stage renal disease (ESRD), but the therapeutic strategies for DKD are still limited. Red radishes (Raphanus sativus L.) are a rich source of natural anthocyani
Externí odkaz:
https://doaj.org/article/904415de456541c081085aed8311118d
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-18 (2024)
Abstract The co-existence of inflammatory bowel disease (IBD) and non-alcoholic steatohepatitis (NASH) has raised interest in identifying shared molecular mechanisms and potential therapeutic targets. However, the relationship between these two disea
Externí odkaz:
https://doaj.org/article/730aa458bc7b43d8ad0470ab4002c541
Autor:
Minxuan Xu, Jun Tan, Xin Liu, Li Han, Chenxu Ge, Yujie Zhang, Fufang Luo, Zhongqin Wang, Xiaoqin Xue, Liangyin Xiong, Xin Wang, Qinqin Zhang, Xiaoxin Wang, Qin Tian, Shuguang Zhang, Qingkun Meng, Xianling Dai, Qin Kuang, Qiang Li, Deshuai Lou, Linfeng Hu, Xi Liu, Gang Kuang, Jing Luo, Chunxiao Chang, Bochu Wang, Jie Chai, Shengbin Shi, Lianyi Han
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-22 (2023)
Abstract Currently potential preclinical drugs for the treatment of nonalcoholic steatohepatitis (NASH) and NASH-related pathopoiesis have failed to achieve expected therapeutic efficacy due to the complexity of the pathogenic mechanisms. Here we sho
Externí odkaz:
https://doaj.org/article/943a31ce33744632ade862d192f16e2d
Autor:
Chenxu Ge, Jun Tan, Deshuai Lou, Liancai Zhu, Zixuan Zhong, Xianling Dai, Yan Sun, Qin Kuang, Junjie Zhao, Longyan Wang, Jin Liu, Bochu Wang, Minxuan Xu
Publikováno v:
Redox Biology, Vol 68, Iss , Pp 102953- (2023)
Externí odkaz:
https://doaj.org/article/8b382a1242d7440c9005fa827257fd13
Autor:
Minxuan Xu, Jun Tan, Liancai Zhu, Chenxu Ge, Yi Zhang, Fufeng Gao, Xianling Dai, Qin Kuang, Jie Chai, Benkui Zou, Bochu Wang
Publikováno v:
Advanced Science, Vol 10, Iss 36, Pp n/a-n/a (2023)
Externí odkaz:
https://doaj.org/article/b2b03cd6c69e4d4b872a65033fbc624e
Autor:
Minxuan Xu, Jun Tan, Liancai Zhu, Chenxu Ge, Wei Dong, Xianling Dai, Qin Kuang, Shaoyu Zhong, Lili Lai, Chao Yi, Qiang Li, Deshuai Lou, Linfeng Hu, Xi Liu, Gang Kuang, Jing Luo, Jing Feng, Bochu Wang
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 13, Iss 3, Pp 1071-1092 (2023)
Nowadays potential preclinical drugs for the treatment of nonalcoholic steatohepatitis (NASH) have failed to achieve expected therapeutic efficacy because the pathogenic mechanisms are underestimated. Inactive rhomboid protein 2 (IRHOM2), a promising
Externí odkaz:
https://doaj.org/article/2496923f2e6942078d6f996b083ac336
Autor:
Chenxu Ge, Jun Tan, Xianling Dai, Qin Kuang, Shaoyu Zhong, Lili Lai, Chao Yi, Yan Sun, Jing Luo, Chufeng Zhang, Liancai Zhu, Bochu Wang, Minxuan Xu
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-21 (2022)
Mechanisms underlying the pathogenesis of nonalcoholic steatohepatitis are unclear. Here, the authors show that ROS-mediated DUSP22 degradation participates in the progression of fatty liver, contributing to the development of NASH and associated HCC
Externí odkaz:
https://doaj.org/article/5ea402ac4e5241809e0364f9ae48f4ff
Autor:
Minxuan Xu, Jun Tan, Wei Dong, Benkui Zou, Xuepeng Teng, Liancai Zhu, Chenxu Ge, Xianling Dai, Qin Kuang, Shaoyu Zhong, Lili Lai, Chao Yi, Tingting Tang, Junjie Zhao, Longyan Wang, Jin Liu, Hao Wei, Yan Sun, Qiufeng Yang, Qiang Li, Deshuai Lou, Linfeng Hu, Xi Liu, Gang Kuang, Jing Luo, Mingxin Xiong, Jing Feng, Chufeng Zhang, Bochu Wang
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-20 (2022)
Nonalcoholic steatohepatitis (NASH) is a chronic liver disease with complex disease mechanisms. Here the authors report that the E3 ubiquitin-protein ligase Trim31 mitigates development of NASH via inhibition of rhomboid 5 homolog 2 (Rhbdf2) in mice.
Externí odkaz:
https://doaj.org/article/21bc4d0042064139960459afd8cbe022
Autor:
Yanrong Ren, Shiwen Hu, Hongzheng Pu, Ying Zhou, Mingzhu Jiang, Yuanyuan Li, Chaofang Deng, Jie Gao, Minxuan Xu, Chenxu Ge
Publikováno v:
Journal of Functional Foods, Vol 98, Iss , Pp 105263- (2022)
Depression is a widespread mental disorder with extremely complex pathogenesis, and its effective treatment still requires to be solved. Juglanin (Jug) is a natural compound with anti-inflammatory, antioxidant and anti-tumor effects, but whether it s
Externí odkaz:
https://doaj.org/article/7e71e38688ea4d2a9f39e0a618656508
Autor:
Chenxu, Ge, Shaoyu, Zhong, Lili, Lai, Dai, Xianling, Kuang, Qin, Qiang, Li, Linfeng, Hu, Deshuai, Lou, Jun, Tan, Minxuan, Xu
Publikováno v:
In Journal of Functional Foods June 2021 81