Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Chenxin Gu"'
Autor:
Ang Luo, Rongrong Hao, Xia Zhou, Yangfan Jia, Changlei Bao, Lei Yang, Lirong Zhou, Chenxin Gu, Ankit A. Desai, Haiyang Tang, Ai-ai Chu
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Pulmonary arterial hypertension (PAH) is a progressive disease characterized by pulmonary vascular remolding and occlusion, leading to the elevated pulmonary arterial pressures, right ventricular hypertrophy, and eventual heart failure if le
Externí odkaz:
https://doaj.org/article/0a243434c1294130bac52baee3687e36
Autor:
Zan Huang, Chenxin Gu, Zengdi Zhang, Rini Arianti, Aneesh Swaminathan, Kevin Tran, Alex Battist, Endre Kristóf, Hai-Bin Ruan
Publikováno v:
PLoS Biology, Vol 21, Iss 12, p e3002413 (2023)
Brown adipose tissue (BAT) dissipates energy as heat, contributing to temperature control, energy expenditure, and systemic homeostasis. In adult humans, BAT mainly exists in supraclavicular areas and its prevalence is associated with cardiometabolic
Externí odkaz:
https://doaj.org/article/1e35e6c2b66447528c681e7d46e52970
Autor:
Ang Luo, Yangfan Jia, Rongrong Hao, Yafang Yu, Xia Zhou, Chenxin Gu, Meijuan Ren, Haiyang Tang
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 11, p 9629 (2023)
Pulmonary arterial hypertension (PAH) is a rare but fatal disease characterized by elevated pulmonary vascular resistance and increased pressure in the distal pulmonary arteries. Systematic analysis of the proteins and pathways involved in the progre
Externí odkaz:
https://doaj.org/article/5bd0f619ba144f928b1c5cb32e33412a
Autor:
Evgeny A. Zemskov, Christine M. Gross, Saurabh Aggarwal, Marina A. Zemskova, Xiaomin Wu, Chenxin Gu, Ting Wang, Haiyang Tang, Stephen M. Black
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
In acute lung injury (ALI), the NF-κB-mediated downregulation of Sox18 gene expression leads to the disruption of the pulmonary endothelial barrier. Previous studies have suggested that the action of NF-κB as a transcriptional repressor also requir
Externí odkaz:
https://doaj.org/article/872767de9a5d4a08b5affe0f28d47853
Autor:
Yinan Shi, Chenxin Gu, Tongtong Zhao, Yangfan Jia, Changlei Bao, Ang Luo, Qiang Guo, Ying Han, Jian Wang, Stephen M. Black, Ankit A. Desai, Haiyang Tang
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Rationale: Enhanced proliferation and distal migration of human pulmonary arterial smooth muscle cells (hPASMCs) both contribute to the progressive increases in pulmonary vascular remodeling and resistance in pulmonary arterial hypertension (PAH). Ou
Externí odkaz:
https://doaj.org/article/4181b4427f0545c1b2cfbd7f1951f13d
Autor:
Xiaoting Yao, Tian Jing, Tianxing Wang, Chenxin Gu, Xi Chen, Fengqiang Chen, Hao Feng, Huiying Zhao, Dekun Chen, Wentao Ma
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
Background: Pulmonary arterial hypertension (PAH) is a life-threatening chronic cardiopulmonary disease. However, there are limited studies reflecting the available biomarkers from separate gene expression profiles in PAH. This study explored two mic
Externí odkaz:
https://doaj.org/article/72d1644812a64182b4e72b54ee3ac6ff
Autor:
Zhongkai Zhu, Dureti Godana, Ailing Li, Bianca Rodriguez, Chenxin Gu, Haiyang Tang, Richard D. Minshall, Wei Huang, Jiwang Chen
Publikováno v:
Pulmonary Circulation, Vol 9 (2019)
Echocardiography, a non-invasive and cost-effective method for monitoring cardiac function, is commonly used for evaluation and pre-clinical diagnostics of pulmonary hypertension (PH). Previous echocardiographic studies in experimental models of PH a
Externí odkaz:
https://doaj.org/article/41703fce41c8475685f40db7bffa0dfa
Autor:
Tang, Ang Luo, Yangfan Jia, Rongrong Hao, Yafang Yu, Xia Zhou, Chenxin Gu, Meijuan Ren, Haiyang
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 11; Pages: 9629
Pulmonary arterial hypertension (PAH) is a rare but fatal disease characterized by elevated pulmonary vascular resistance and increased pressure in the distal pulmonary arteries. Systematic analysis of the proteins and pathways involved in the progre
Autor:
David Caraballo, Marina Zemskova, Santiago Moreno, Tania Torres, Chenxin Gu, Manivannan Yegambaram, Haiyang Tang, Kim Tieu, Stephen Black, Evgeny Zemskov
Publikováno v:
Free Radical Biology and Medicine. 192:55-56
Autor:
Hai-Jian Sun, Hui-Ping Wang, Stephen M. Black, Qiong Du, Haiyang Tang, Chenxin Gu, Feng Zhang, Ying Han, Shuo Sun, Yu Xu
Publikováno v:
Antioxidants & Redox Signaling. 31:1352-1370
Aims: Vascular calcification (VC) is a hallmark feature of cardiovascular disease and a significant risk factor for morbidity and mortality. Salusin-β exerts cardiovascular regulating effects in hypertension, atherosclerosis, and diabetes. The prese