Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Chenxia He"'
Autor:
Yabing Hu, Xuewen Hu, Dongchen Li, Zhenzhen Du, Kun Shi, Chenxia He, Ying Zhang, Donglei Zhang
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
During oocyte maturation and the oocyte-to-embryo transition, key developmental regulators such as RNA-binding proteins coordinate translation of particular messenger RNA (mRNAs) and related developmental processes by binding to their cognate materna
Externí odkaz:
https://doaj.org/article/2245f5146d47421aafb5044365584008
Autor:
Diego R. Coelho, Flavio R. Palma, Veronica Paviani, Chenxia He, Jeanne M. Danes, Yunping Huang, Juliana C. P. Calado, Peter C. Hart, Cristina M. Furdui, Leslie B. Poole, Matthew J. Schipma, Marcelo G. Bonini
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 119(29)
The dichotomous behavior of superoxide dismutase-2 (SOD2) in cancer biology has long been acknowledged and more recently linked to different posttranslational forms of the enzyme. However, a distinctive activity underlying its tumor-promoting functio
Autor:
Benjamin N. Gantner, Marcelo G. Bonini, Diego R. Coelho, Chenxia He, Jeanne M. Danes, Veronica Paviani, Flavio R. Palma
Publikováno v:
Antioxid Redox Signal
Significance: Reactive oxygen species (ROS) are now widely recognized as central mediators of cell signaling. Mitochondria are major sources of ROS. Recent Advances: It is now clear that mitochondrial ROS are essential to activate responses to cellul
Autor:
Chenxia He, Benjamin N. Gantner, Andre L. P de Abreu, Joseph O'Brien, Jacek Zielonka, Marcelo G. Bonini, Lalage M. Wakefield, Binwu Tang, David Gius, Angela Mathison, Erich Stauder, Raul Urrutia, Jeanne M. Danes, Jonna Frasor, Peter C. Hart, Douglas Ganini, Yueming Zhu, Yunping Huang
Publikováno v:
Proceedings of the National Academy of Sciences. 116:23534-23541
Mitochondrial superoxide dismutase (SOD2) suppresses tumor initiation but promotes invasion and dissemination of tumor cells at later stages of the disease. The mechanism of this functional switch remains poorly defined. Our results indicate that as
Autor:
Coelho, Diego R., Palma, Flavio R., Paviani, Veronica, Chenxia He, Danes, Jeanne M., Yunping Huang, Calado, Juliana C. P., Hart, Peter C., Furdui, Cristina M., Poole, Leslie B., Schipma, Matthew J., Bonini, Marcelo G.
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America; 7/19/2022, Vol. 119 Issue 29, p1-12, 22p
Publikováno v:
Trends in Biochemical Sciences. 41:568-577
ATP and reactive oxygen species (ROS) are signaling molecules that control cellular function and phenotype. Mitochondria produce both ATP and ROS. Since the electrons needed to generate either ATP or ROS originate from NADH/FADH2, the mechanism throu
Publikováno v:
Free Radical Biology and Medicine. 128:S100-S101
Macrophages play a critical role in inflammation initiation, progression and resolution due to their capacity to assume both pro- and anti-inflammatory phenotypes. The molecular mechanisms that regulate these transitions are of great clinical interes
Autor:
Douglas Ganini da Silva, Peter C. Hart, David Gius, Marcelo G. Bonini, Chenxia He, Yueming Zhu
Publikováno v:
Free Radical Biology and Medicine. 128:S62-S63
Mitochondrial superoxide dismutase (SOD2) displays a dichotomous role in cancer, being a suppressor of tumor initiation while stimulating cancer progression later in the established disease. The mechanistic basis of this switch remains unknown. Our r
Autor:
Marcelo G. Bonini, Micaela Vargas, Chenxia He, Peter C. Hart, Kraig Thieraud, Kristine Fricano, André Luelsdorf Pimenta de Abreu
Publikováno v:
The FASEB Journal. 31
Reactive oxygen species (ROS) largely originating in the mitochondria play essential roles in the metabolic and (epi)genetic reprogramming of cancer cell evolution towards more aggressive phenotypes. Recent studies have indicated that the activity of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cede716a09ba5ee8bd2032882e36520
https://europepmc.org/articles/PMC5689482/
https://europepmc.org/articles/PMC5689482/