Identification of a Novel Protein-Based Prognostic Model in Gastric Cancers

Autor: Zhijuan Xiong, Chutian Xing, Ping Zhang, Yunlian Diao, Chenxi Guang, Ying Ying, Wei Zhang

Publikováno v: Biomedicines, Vol 11, Iss 3, p 983 (2023)

Gastric cancer (GC) is the third leading cause of cancer-related deaths worldwide. However, there are still no reliable biomarkers for the prognosis of this disease. This study aims to construct a robust protein-based prognostic prediction model for

Externí odkaz: https://doaj.org/article/f0595b8970664cb994d72e1c42f4c756

LC–MS/MS Method for Simultaneous Determination of Linarin and Its Metabolites in Rat Plasma and Liver Tissue Samples: Application to Pharmacokinetic and Liver Tissue Distribution Study After Oral Administration of Linarin

Autor: Yang Li, Chenxi Guang, Na Zhao, Xinchi Feng, Feng Qiu

Publikováno v: Molecules, Vol 24, Iss 18, p 3342 (2019)

Linarin, a flavone glycoside, is considered to be a promising natural product due to its diverse pharmacological activities. Recently, it has been brought into focus for its potential to treat liver failure. In this study, a rapid and sensitive liqui

Externí odkaz: https://doaj.org/article/3524ef21ffe34028b8e6713de9eb3dd6

New withanolides from Physalis minima and their cytotoxicity against A375 human melanoma cells

Autor: Ning Kang, Feng Qiu, Xinya He, Liqin Ding, Shijie Cao, Lixia Chen, Benke Jiang, Meng Zhang, Chenxi Guang, Bing-Yang Zhang

Publikováno v: RSC Advances. 10:22819-22827

Seven previously undescribed withanolides, namely physaminilide A–G (1–7), and two artificial withanolides (8–9), along with 10 known analogues (10–19) were isolated from Physalis minima. The structures were established by spectroscopic analy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d91b383e8c8b42960cf2604caee89dbb
https://doi.org/10.1039/d0ra04106h

New withanolides from

Autor: Meng, Zhang, Bingyang, Zhang, Chenxi, Guang, Benke, Jiang, Xinya, He, Shijie, Cao, Liqin, Ding, Ning, Kang, Lixia, Chen, Feng, Qiu

Publikováno v: RSC advances. 10(38)

Seven previously undescribed withanolides, namely physaminilide A-G (1-7), and two artificial withanolides (8-9), along with 10 known analogues (10-19) were isolated from

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::549901b624d8ca01497ef35e2a255c2b
https://pubmed.ncbi.nlm.nih.gov/35514550

Characterization of the In Vivo and In Vitro Metabolites of Linarin in Rat Biosamples and Intestinal Flora Using Ultra-High Performance Liquid Chromatography Coupled with Quadrupole Time-of-Flight Tandem Mass Spectrometry

Autor: Chenxi Guang, Miao Qiao, Liwei Chai, Xinchi Feng, Feng Qiu, Yang Li, Tong Wang

Publikováno v: Molecules : A Journal of Synthetic Chemistry and Natural Product Chemistry
Molecules
Volume 23
Issue 9
Molecules, Vol 23, Iss 9, p 2140 (2018)

Linarin, a flavone glycoside, is considered to be a promising natural product due to its diverse pharmacological activities, including analgesic, antipyretic, anti-inflammatory and hepatoprotective activities. In this research, the metabolites of lin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f51cad0e1851fb84b78b836c0ae7510
https://doi.org/10.3390/molecules23092140