Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Chenqu Suo"'
Autor:
Chenqu Suo, Krzysztof Polanski, Emma Dann, Rik G. H. Lindeboom, Roser Vilarrasa-Blasi, Roser Vento-Tormo, Muzlifah Haniffa, Kerstin B. Meyer, Lisa M. Dratva, Zewen Kelvin Tuong, Menna R. Clatworthy, Sarah A. Teichmann
Publikováno v:
Nature Biotechnology.
Assessment of single-cell gene expression (single-cell RNA sequencing) and adaptive immune receptor (AIR) sequencing (scVDJ-seq) has been invaluable in studying lymphocyte biology. Here we introduce Dandelion, a computational pipeline for scVDJ-seq a
Autor:
Dinithi Sumanaweera, Chenqu Suo, Ana-Maria Cujba, Daniele Muraro, Emma Dann, Krzysztof Polanski, Alexander S. Steemers, Woochan Lee, Amanda J. Oliver, Jong-Eun Park, Kerstin B. Meyer, Bianca Dumitrascu, Sarah A. Teichmann
Single-cell data analysis can infer dynamic changes in cell populations, for example across time, space or in response to perturbation. To compare these dynamics between two conditions, trajectory alignment via dynamic programming (DP) optimization i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::332ab57f231f633a9c123b765a34bbbb
https://doi.org/10.1101/2023.03.08.531713
https://doi.org/10.1101/2023.03.08.531713
Autor:
Josephine L. Barnes, Peng He, Masahiro Yoshida, Kaylee B. Worlock, Rik G.H. Lindeboom, Chenqu Suo, J. Patrick Pett, Anna Wilbrey-Clark, Emma Dann, Lira Mamanova, Laura Richardson, Amanda J. Oliver, Adam Pennycuick, Jessica Allen-Hyttinen, Iván T. Herczeg, Robert E. Hynds, Vitor H. Teixeira, Muzlifah Haniffa, Kyungtae Lim, Dawei Sun, Emma L. Rawlins, Krzysztof Polanski, Paul A. Lyons, John C. Marioni, Zewen Kelvin Tuong, Menna R. Clatworthy, James L. Reading, Sam M. Janes, Sarah A. Teichmann, Kerstin B. Meyer, Marko Z. Nikolić
During human development, lungs develop their roles of gas exchange and barrier function. Recent single cell studies have focused on epithelial and mesenchymal cell types, but much less is known about the developing lung immune cells, although the ai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ba9e470f99f21542bfed3c556bfdae9f
https://doi.org/10.1101/2022.12.13.519713
https://doi.org/10.1101/2022.12.13.519713
Autor:
Chenqu Suo, Krzysztof Polanski, Emma Dann, Rik G.H. Lindeboom, Roser Vilarrasa-Blasi, Roser Vento-Tormo, Muzlifah Haniffa, Kerstin B. Meyer, Lisa M. Dratva, Zewen Kelvin Tuong, Menna R. Clatworthy, Sarah A. Teichmann
Assessment of single-cell gene expression (scRNA-seq) and adaptive immune receptor sequencing (scVDJ-seq) has been invaluable in studying lymphocyte biology. Here, we introduceDandelion, a computational pipeline for scVDJ-seq analysis. It enables the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b95ca1a60749960bbce524f1eb989af1
https://doi.org/10.1101/2022.11.18.517068
https://doi.org/10.1101/2022.11.18.517068
Autor:
Alexander Predeus, Anna Arutyunyan, Laura Jardine, Chenqu Suo, Emma Dann, Regina Hoo, Martin Prete, Muzlifah Haniffa, Thomas J. Mitchell, Roser Vento-Tormo, Matthew D. Young
Human females undergo X-inactivation (Xi), whereby one copy of X is randomly inactivated early in development, then propagated through cell division. Because Xi state is inherited, its measurement in populations of cells encodes information about the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2423a988e4866ce369dc8af500382d7f
https://doi.org/10.1101/2022.11.10.515645
https://doi.org/10.1101/2022.11.10.515645
Autor:
Chenqu Suo, Daphne Chia, Andoni Toms, Anish Sanghrajka, Athimalaipet Ramanan, Orla Killeen, Benjamin Jacobs, Cristina Ilea, Kamran Mahmood, Sandrine Compeyrot-Lacassagne, Kate Armon
Publikováno v:
Rheumatology Advances in Practice. 6
Introduction/Background Chronic Recurrent Multifocal Osteomyelitis (CRMO), also known as chronic nonbacterial osteomyelitis (CNO), is a rare autoinflammatory condition affecting the bones. It occurs primarily in children and teenagers and is characte
Autor:
Rachel A Botting, Issac Goh, Antony Rose, Simone Webb, Justin Engelbert, Yorick Gitton, Emily Stephenson, Mariana Quiroga Londoño, Michael Mather, Nicole Mende, Ivan Imaz-Rosshandler, Dave Horsfall, Daniela Basurto-Lozada, Nana-Jane Chipampe, Victoria Rook, Pavel Mazin, MS Vijayabaskar, Rebecca Hannah, Laure Gambardella, Kile Green, Stephane Ballereau, Megumi Inoue, Liz Tuck, Valentina Lorenzi, Kwasi Kwakwa, Clara Alsinet, Bayanne Olabi, Mohi Miah, Chloe Admane, Dorin-Mirel Popescu, Meghan Acres, David Dixon, Rowen Coulthard, Steven Lisgo, Deborah J Henderson, Emma Dann, Chenqu Suo, Sarah J Kinston, Jong-eun Park, Krzysztof Polanski, Stijn Van Dongen, Kerstin B Meyer, Marella de Bruijn, James Palis, Sam Behjati, Elisa Laurenti, Nicola K Wilson, Roser Vento-Tormo, Alain Chédotal, Omer Bayraktar, Irene Roberts, Laura Jardine, Berthold Göttgens, Sarah A Teichmann, Muzlifah Haniffa
The yolk sac (YS) represents an evolutionarily-conserved extraembryonic structure that ensures timely delivery of nutritional support and oxygen to the developing embryo. However, the YS remains ill-defined in humans. We therefore assemble a complete
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::40063609b64ec1d12691d74d2fc5041c
https://doi.org/10.1101/2022.08.03.502475
https://doi.org/10.1101/2022.08.03.502475
Autor:
Chenqu Suo, Emma Dann, Issac Goh, Laura Jardine, Vitalii Kleshchevnikov, Jong-Eun Park, Rachel A. Botting, Emily Stephenson, Justin Engelbert, Zewen Kelvin Tuong, Krzysztof Polanski, Nadav Yayon, Chuan Xu, Ondrej Suchanek, Rasa Elmentaite, Cecilia Domínguez Conde, Peng He, Sophie Pritchard, Mohi Miah, Corina Moldovan, Alexander S. Steemers, Martin Prete, John C. Marioni, Menna R. Clatworthy, Muzlifah Haniffa, Sarah A. Teichmann
Recent advances in single cell genomics technologies have facilitated studies on the developing immune system at unprecedented scale and resolution. However, these studies have focused on one or a few organs and were thus limited in understanding the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b5490c12be85c8ef4217f4f5b80e0358
https://doi.org/10.1101/2022.01.17.476665
https://doi.org/10.1101/2022.01.17.476665
Autor:
Peng He, Kyungtae Lim, Dawei Sun, Jan Patrick Pett, Quitz Jeng, Krzysztof Polanski, Ziqi Dong, Liam Bolt, Laura Richardson, Lira Mamanova, Monika Dabrowska, Anna Wilbrey-Clark, Elo Madissoon, Zewen Kelvin Tuong, Emma Dann, Chenqu Suo, Isaac Goh, Masahiro Yoshida, Marko Z Nikolić, Sam M Janes, Xiaoling He, Roger A Barker, Sarah A Teichmann, John C. Marioni, Kerstin B Meyer, Emma L Rawlins
Publikováno v:
Cell. 185:4841-4860.e25
We present a multiomic cell atlas of human lung development that combines single cell RNA and ATAC sequencing, high throughput spatial transcriptomics and single cell imaging. Coupling single cell methods with spatial analysis has allowed a comprehen
Autor:
Jongeun Park, Veronika Kedlian, Chenqu Suo, Liam Bolt, Alexander Steemers, Nadav Yayon, Sarah Teichmann
This Protocol is intended for human Thymus single cell dissociation. It includes tissue preservation and handling, Enzymatic dissociation, FACS an MACS enrichments. Developed In the Teichmann lab at the Sanger institute, Wellcome Gemone Campus, UK VK
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3b9761bae3db5e77cc2e5a7b3da3c223
https://doi.org/10.17504/protocols.io.bx8sprwe
https://doi.org/10.17504/protocols.io.bx8sprwe