Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Chenjun Zhai"'
Autor:
Xiaofeng Yuan, Jun Chen, Dingsen Shi, Jiaxun Song, Pu Wang, Dong Cheng, Cheng Yang, Xubin Qiu, Chenjun Zhai
Publikováno v:
Heliyon, Vol 10, Iss 1, Pp e23510- (2024)
Esophageal cancer (EC) is a common and devastating tumor of the upper digestive tract. Unfortunately, by the time any symptoms have manifested, the disease has often progressed to an advanced stage and is accompanied by macro- and micrometastases, in
Externí odkaz:
https://doaj.org/article/ec8ee4557ed64f38b1519bfb6b505fb7
Publikováno v:
Journal of Immunology Research, Vol 2023 (2023)
Dysregulation of miRNAs in chondrocytes has been confirmed to participate in osteoarthritis (OA) progression. Previous study has screen out several key miRNAs may play crucial role in OA based on bioinformatic analysis. Herein, we identified the down
Externí odkaz:
https://doaj.org/article/eb8f0e24eaae49efa9d6628f0bcb5fb2
Autor:
Kai Yan, Xiao Zhang, Yang Liu, Jiangqi Cheng, Chenjun Zhai, Kai Shen, Wenwei Liang, Weimin Fan
Publikováno v:
Materials & Design, Vol 225, Iss , Pp 111531- (2023)
Repairing articular cartilage defects remains a clinical challenge. 3D bioprinting scaffolds to repair articular cartilage defects is a research hotspot nowadays. In this study, we used silk fibroin (SF) and hydroxypropyl cellulose methacrylate (HPCM
Externí odkaz:
https://doaj.org/article/84a3ac5a1ab94ec093d4cafdd6a0be20
Autor:
Chenjun Zhai, Qiang Zuo, Kai Shen, Jinchun Zhou, Jun Chen, Xiao Zhang, Chunyang Luo, Hao Fei, Weimin Fan
Publikováno v:
Materials & Design, Vol 193, Iss , Pp 108766- (2020)
The application of multilayered monolithic scaffolds to repair osteochondral defects has become a hot research topic due to the advantage of simulating native osteochondral physiological structure. However, it was difficult to promote proliferation a
Externí odkaz:
https://doaj.org/article/b881f339bea04439b3beab289469ed73
Publikováno v:
Cellular Physiology and Biochemistry, Vol 44, Iss 4, Pp 1509-1525 (2017)
Background/Aims: Periodic mechanical stress could significantly promote chondrocyte proliferation and matrix synthesis. However, the mechanisms underlying the ability of chondrocyte detecting and responding to periodic mechanical stimuli have not bee
Externí odkaz:
https://doaj.org/article/adaec420c9124477ba13a7dfd0f92791
Autor:
Wenwei Liang, Chunhui Zhu, Feng Liu, Weiding Cui, Qing Wang, Zhefeng Chen, Qijia Zhou, Shun Xu, Chenjun Zhai, Weimin Fan
Publikováno v:
Cellular Physiology and Biochemistry, Vol 37, Iss 4, Pp 1301-1314 (2015)
Background/Aims: Periodic mechanical stress activates integrin β1-initiated signal pathways to promote chondrocyte proliferation and matrix synthesis. Integrin β1 overexpression has been demonstrated to play important roles in improving the activit
Externí odkaz:
https://doaj.org/article/1f2e78a3f8524ba184cf18316429a3da
Autor:
Gentao Fan, Yan Zhu, Hao Zhu, Lingfeng Yu, Zhen Wang, Chenjun Zhai, Guangxin Zhou, Jianning Zhao, Yicun Wang
Publikováno v:
BioMed Research International. 2023:1-22
Background. Osteosarcoma (OS) is the most common primary aggressive sarcoma of bone, with massive aberrant expression of oncogenes related to the development of OS. RALA, a kind of small Ras-like guanosine triphosphatases, has been identified as a po
Publikováno v:
Joint Diseases and Related Surgery
Objectives This study aims to explore the mechanism by which osteoblast autophagy participated in glucocorticoid-induced femoral head necrosis (FHN). Materials and methods Thirty male specific-pathogen-free C57 mice (age, one month; weighing 20-25 g)
Autor:
Zhen Wang, Yang Liu, Hao Fei, Jiyong Zhang, Weimin Fan, Chenjun Zhai, Tao Xu, Chunyang Luo, Xiao Zhang, Yanzi Ding
Publikováno v:
Tissue Engineering Part C: Methods. 24:645-658
This study presented a new method to fabricate SF-ECM scaffolds that potentially promote chondrogenesis of BMSCs, and open up new possibilities for using SF-ECM scaffolds as an off-the-shelf strategy for joint cartilage regeneration. It is worthy of
Autor:
Chenjun Zhai, Hao Fei, Junzheng Hu, Zhen Wang, Shun Xu, Qiang Zuo, Zeng Li, Wenwei Liang, Weimin Fan
Publikováno v:
Tissue Engineering Part A. 24:1680-1692
Repair of articular cartilage defects using bilayered scaffolds is problematic because tissue-engineered cartilage is prone to overgrowth toward subchondral bone, resulting in structural abnormalities of cartilage and subchondral bone. A "twice freez