Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Chenji, Ye"'
Autor:
Jinjie Duan, Wenhui Dong, Guangyan Wang, Wenjing Xiu, Guangyin Pu, Jingwen Xu, Chenji Ye, Xu Zhang, Yi Zhu, Chunjiong Wang
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract Aging is a major risk factor for metabolic disorders. Polyunsaturated fatty acid-derived bioactive lipids play critical roles as signaling molecules in metabolic processes. Nonetheless, their effects on age-related liver steatosis remain unk
Externí odkaz:
https://doaj.org/article/dfc2a3621cbf413c9d67a8daa3b519d8
Autor:
Wenli Liu, Chenji Ye, Qian Cheng, Xuejiao Zhang, Liu Yao, Qi Li, Jing Huang, Yajin Liu, Zhengsheng Zou, Hua Wang, Jun Yan, Yi Zhu, Chunjiong Wang, Ding Ai
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 7, Iss 1, Pp 211-231 (2019)
Background & Aims: Nonalcoholic steatohepatitis (NASH) is an increasingly prevalent nonalcoholic fatty liver disease, characterized by inflammatory cell infiltration and hepatocellular damage. Mammalian target of rapamycin complex 1 (mTORC1) has been
Externí odkaz:
https://doaj.org/article/084e471017ef42d38e31fdc5f2c1da3e
Autor:
Weijia Cheng, Can Cui, Gang Liu, Chenji Ye, Fang Shao, Ashim K. Bagchi, Jawahar L. Mehta, Xianwei Wang
Publikováno v:
Cardiovascular drugs and therapyReferences.
Cardiovascular diseases (CVDs) are the leading cause of death globally. Atherosclerosis is the basis of major CVDs - myocardial ischemia, heart failure, and stroke. Among numerous functional molecules, the transcription factor nuclear factor κB (NF-
Autor:
Guangyan, Wang, Jinjie, Duan, Guangyin, Pu, Chenji, Ye, Yue, Li, Wenjing, Xiu, Jingwen, Xu, Ben, Liu, Yi, Zhu, Chunjiong, Wang
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1868:166413
The mechanisms underlying the progression of liver disease from simple hepatic steatosis to advanced nonalcoholic steatohepatitis (NASH) and liver fibrosis warrant further investigation. Increased mRNA levels of Annexin A2 protein (Anxa2) have been o
Autor:
Chenji Ye, Jinjie Duan, Xuejiao Zhang, Yayue Song, Liu Yao, Ding Ai, Qi Li, Yi Zhu, Chunjiong Wang, Biqing Wang, Guangyan Wang
Publikováno v:
Science China. Life sciences. 64(3)
Targeting the white-to-brown fat conversion is important for developing potential strategies to counteract metabolic diseases; yet the mechanisms are not fully understood. Yes-associated-protein (YAP), a transcription co-activator, was demonstrated t
Autor:
Jun Yan, Ding Ai, Chunjiong Wang, Chenji Ye, Wenli Liu, Yajin Liu, Hua Wang, Qian Cheng, Zhengsheng Zou, Jing Huang, Yi Zhu, Qi Li, Liu Yao, Xuejiao Zhang
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 7, Iss 1, Pp 211-231 (2019)
Cellular and Molecular Gastroenterology and Hepatology, Vol 7, Iss 1, Pp 211-231 (2019)
Background & Aims Nonalcoholic steatohepatitis (NASH) is an increasingly prevalent nonalcoholic fatty liver disease, characterized by inflammatory cell infiltration and hepatocellular damage. Mammalian target of rapamycin complex 1 (mTORC1) has been
Autor:
Fengxia Xue, Yingmei Wang, Yajin Liu, Jinlong He, Xu Zhang, Liyuan Peng, Ding Ai, Yi Zhu, Chenji Ye, Jing Huang, Dan Li, Xuan Fang
Publikováno v:
British Journal of Pharmacology. 175:1190-1204
Background and purpose Atherosclerosis results from a maladaptive inflammatory response initiated by the intramural retention of LDL in susceptible areas of the arterial vasculature. The ω-3 polyunsaturated fatty acids (ω-3) have protective effects
Autor:
Xuejiao Zhang, Liu Yao, Hongfeng Jiang, Yi Zhu, Chunjiong Wang, Xu Zhang, Ding Ai, Wenli Liu, Chenji Ye, Jinlong He
Publikováno v:
British Journal of Pharmacology. 174:2358-2372
Background and purpose The ω-3 polyunsaturated fatty acids (PUFAs) mediate protective effects on several metabolic disorders. However, the functions of their metabolites in the early stage of nonalcoholic fatty liver disease (NAFLD) are largely unkn
Autor:
Sung Hee Hwang, Xu Zhang, Bruce D. Hammock, Boyang Cao, Liu Yao, Wenli Liu, Chunjiong Wang, Chenji Ye, Yi Zhu, Ding Ai, Jing Liang, Lu Tan, Qian Cheng, Jinlong He, Wenbin Cai, Bochuan Li, Meng Yan
Hepatic steatosis is the beginning phase of nonalcoholic fatty liver disease, and hyperhomocysteinemia (HHcy) is a significant risk factor. Soluble epoxide hydrolase (sEH) hydrolyzes epoxyeicosatrienoic acids (EETs) and other epoxy fatty acids, atten
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::420054f3b8fb496a2f677728365020fe
https://europepmc.org/articles/PMC6483021/
https://europepmc.org/articles/PMC6483021/