Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Chenhui Zou"'
Autor:
Biao Tang, Chenhui Zou, Stefan Schwarz, Chunyan Xu, Wenbo Hao, Xiao-Mei Yan, Yuting Huang, Juan Ni, Hua Yang, Xiang-Dang Du, Xinxin Shan
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 3 (2023)
ABSTRACT The aim of this study was to investigate the transferability of acquired linezolid resistance genes and associated mobile genetic elements in an Enterococcus faecalis isolate QZ076, cocarrying optrA, cfr, cfr(D), and poxtA2 genes. MICs were
Externí odkaz:
https://doaj.org/article/1e804f1dc3544e9a82bcaed672b6cce8
Autor:
Chenhui Zou, Imane El Dika, Koen O. A. Vercauteren, Marinela Capanu, Joanne Chou, Jinru Shia, Jill Pilet, Corrine Quirk, Gadi Lalazar, Linda Andrus, Mohammad Kabbani, Amin Yaqubie, Danny Khalil, Taha Mergoub, Luis Chiriboga, Charles M. Rice, Ghassan K. Abou‐Alfa, Ype P. de Jong
Publikováno v:
Cancer Medicine, Vol 11, Iss 3, Pp 602-617 (2022)
Abstract Background Hepatocellular carcinoma (HCC) patient‐derived xenograft (PDX) models hold potential to advance knowledge in HCC biology to help improve systemic therapies. Beside hepatitis B virus‐associated tumors, HCC is poorly established
Externí odkaz:
https://doaj.org/article/94c89770dd5544638da6f30f878a4838
Autor:
Moanaro Biswas, Damien Marsic, Ning Li, Chenhui Zou, Gloria Gonzalez-Aseguinolaza, Irene Zolotukhin, Sandeep R.P. Kumar, Jyoti Rana, John S.S. Butterfield, Oleksandr Kondratov, Ype P. de Jong, Roland W. Herzog, Sergei Zolotukhin
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 19, Iss , Pp 347-361 (2020)
Limitations to successful gene therapy with adeno-associated virus (AAV) can comprise pre-existing neutralizing antibodies to the vector capsid that can block cellular entry, or inefficient transduction of target cells that can lead to sub-optimal ex
Externí odkaz:
https://doaj.org/article/05f6a412488548bf8d9ee4437f4100f3
Autor:
Chenhui Zou, Koen O.A. Vercauteren, Eleftherios Michailidis, Mohammad Kabbani, Irene Zoluthkin, Corrine Quirk, Luis Chiriboga, Mustafa Yazicioglu, Xavier M. Anguela, Philip Meuleman, Katherine A. High, Roland W. Herzog, Ype P. de Jong
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 18, Iss , Pp 189-198 (2020)
Adeno-associated virus (AAV) vector serotypes vary in their ability to transduce hepatocytes from different species. Chimeric mouse models harboring human hepatocytes have shown translational promise for liver-directed gene therapies. However, many v
Externí odkaz:
https://doaj.org/article/76e8a94fb75547cf982881d7ea650537
Autor:
Audrey Kapelanski-Lamoureux, Zhouji Chen, Zu-Hua Gao, Ruishu Deng, Anthoula Lazaris, Cynthia Lebeaupin, Lisa Giles, Jyoti Malhotra, Jing Yong, Chenhui Zou, Ype P. de Jong, Peter Metrakos, Roland W. Herzog, Randal J. Kaufman
Publikováno v:
Molecular Therapy. 30:3542-3551
Hemophilia A gene therapy targets hepatocytes to express B domain deleted (BDD) clotting factor VIII (FVIII) to permit viral encapsidation. Since BDD is prone to misfolding in the endoplasmic reticulum (ER) and ER protein misfolding in hepatocytes fo
Autor:
Yingpu Yu, William M. Schneider, Maximilian A. Kass, Eleftherios Michailidis, Ashley Acevedo, Ana L. Pamplona Mosimann, Juliano Bordignon, Alexander Koenig, Christine M. Livingston, Hardeep van Gijzel, Yi Ni, Pradeep M. Ambrose, Catherine A. Freije, Mengyin Zhang, Chenhui Zou, Mohammad Kabbani, Corrine Quirk, Cyprien Jahan, Xianfang Wu, Stephan Urban, Shihyun You, Amir Shlomai, Ype P. de Jong, Charles M. Rice
Publikováno v:
Science Advances. 9
Hepatitis B virus (HBV) chronically infects an estimated 300 million people, and standard treatments are rarely curative. Infection increases the risk of liver cirrhosis and hepatocellular carcinoma, and consequently, nearly 1 million people die each
Autor:
Chenhui Zou, Imane El Dika, Koen O. A. Vercauteren, Marinela Capanu, Joanne Chou, Jinru Shia, Jill Pilet, Corrine Quirk, Gadi Lalazar, Linda Andrus, Mohammad Kabbani, Amin Yaqubie, Danny Khalil, Taha Mergoub, Luis Chiriboga, Charles M. Rice, Ghassan K. Abou‐Alfa, Ype P. de Jong
Publikováno v:
Cancer Medicine, Vol 11, Iss 3, Pp 602-617 (2022)
Background Hepatocellular carcinoma (HCC) patient‐derived xenograft (PDX) models hold potential to advance knowledge in HCC biology to help improve systemic therapies. Beside hepatitis B virus‐associated tumors, HCC is poorly established in PDX.
Autor:
Jyoti Rana, Ning Li, Roland W. Herzog, Chenhui Zou, Irene Zolotukhin, Gloria González-Aseguinolaza, Sergei Zolotukhin, Damien Marsic, Sandeep R. P. Kumar, Ype P. de Jong, Moanaro Biswas, John S.S. Butterfield, Oleksandr Kondratov
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 19, Iss, Pp 347-361 (2020)
Molecular Therapy. Methods & Clinical Development
Molecular Therapy. Methods & Clinical Development
Limitations to successful gene therapy with adeno-associated virus (AAV) can comprise pre-existing neutralizing antibodies to the vector capsid that can block cellular entry, or inefficient transduction of target cells that can lead to sub-optimal ex
Autor:
Mohammad Kabbani, Philip Meuleman, Eleftherios Michailidis, Ype P. de Jong, Corrine Quirk, Chenhui Zou, Luis Chiriboga, Katherine A. High, Mustafa N. Yazicioglu, Koen Vercauteren, Roland W. Herzog, Xavier M. Anguela, Irene Zoluthkin
Publikováno v:
Molecular Therapy. Methods & Clinical Development
MOLECULAR THERAPY-METHODS & CLINICAL DEVELOPMENT
Molecular Therapy: Methods & Clinical Development, Vol 18, Iss, Pp 189-198 (2020)
MOLECULAR THERAPY-METHODS & CLINICAL DEVELOPMENT
Molecular Therapy: Methods & Clinical Development, Vol 18, Iss, Pp 189-198 (2020)
Adeno-associated virus (AAV) vector serotypes vary in their ability to transduce hepatocytes from different species. Chimeric mouse models harboring human hepatocytes have shown translational promise for liver-directed gene therapies. However, many v
Autor:
Ype P. de Jong, Charles M. Rice, Corrine Quirk, Helmuth Gehart, Onur Basak, Carmen López-Iglesias, Anne C. Rios, Peter J. Peters, Susana M. Chuva de Sousa Lopes, Chenhui Zou, Jeroen Korving, Johan H. van Es, Benedetta Artegiani, Luis Chiriboga, Harry Begthel, Hans Clevers, Maaike van den Born, Stephanie Ma, Huili Hu, Florijn Dekkers
Publikováno v:
Cell, 175(6), 1591. Cell Press
Cell, 175(6), 1591-1606.e19. Cell Press
Cell, 175(6), 1591-1606.e19. Elsevier B.V.
Cell, 175(6), 1591
Cell, 175(6), 1591-1606.e19. Cell Press
Cell, 175(6), 1591-1606.e19. Elsevier B.V.
Cell, 175(6), 1591
The mammalian liver possesses a remarkable regenerative ability. Two modes of damage response have been described: (1) The “oval cell” response emanates from the biliary tree when all hepatocytes are affected by chronic liver disease. (2) A massi